A Novel Way for Detection of Antiparkinsonism Drug Entacapone Via Electrodeposition of Silver Nanoparticles/Functionalized Multi-Walled Carbon Nanotubes As an Amperometric Sensor

A Novel Way for Detection of Antiparkinsonism Drug Entacapone Via Electrodeposition of Silver Nanoparticles/Functionalized Multi-Walled Carbon Nanotubes As an Amperometric Sensor Publisher Pubmed

Baghayeri M¹ ; Tehrani MB² ; Amiri A¹ ; Maleki B¹ ; Farhadi S¹

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1. Department of Chemistry, Faculty of Science, Hakim Sabzevari University, P.O. Box 397, Sabzevar, Iran
2. Department of Medicinal Chemistry, Faculty of Pharmacy, Pharmaceutical Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Materials Science and Engineering C Published:2016

Abstract

Silver (Ag) nanoparticles were electrochemically deposited on the film of a metformin functionalized multi-walled carbon nanotube modified glassy carbon electrode (Met-MWCNT/GCE), which fabricated an Ag@Met-MWCNT nanocomposite sensor (Ag@Met-MWCNT/GCE) to detect entacapone (ENT). The Ag@Met-MWCNT nanocomposite was characterized by field emission scanning electrochemical microscopy (FESEM), X-ray diffraction (XRD) analysis, FT-IR and electrochemical tests. The modified electrode showed a large electrocatalytic activity for reduction of ENT. This improved activity indicates that Met@MWCNT plays a crucial role in the dispersion and stabilization of Ag nanoparticles on GCE. Under the optimized conditions the linear range for the detection of the ENT was obtained to be 0.05 to 70.0 μM with a low detection limit of 15.3 nM. The proposed sensor can effectively analyse ENT concentration in pharmaceutical formulations and human urine samples, avoiding interference, and is a promising ENT sensor due to good sensitivity, stability and low cost. © 2016 Elsevier B.V. All rights reserved.

Style	Citing Format
MLA	Baghayeri M, et al.. "A Novel Way for Detection of Antiparkinsonism Drug Entacapone Via Electrodeposition of Silver Nanoparticles/Functionalized Multi-Walled Carbon Nanotubes As an Amperometric Sensor." Materials Science and Engineering C, vol. 66, no. , 2016, pp. 77-83.
APA	Baghayeri M, Tehrani MB, Amiri A, Maleki B, Farhadi S (2016). A Novel Way for Detection of Antiparkinsonism Drug Entacapone Via Electrodeposition of Silver Nanoparticles/Functionalized Multi-Walled Carbon Nanotubes As an Amperometric Sensor. Materials Science and Engineering C, 66(), 77-83.
Chicago	Baghayeri M, Tehrani MB, Amiri A, Maleki B, Farhadi S. "A Novel Way for Detection of Antiparkinsonism Drug Entacapone Via Electrodeposition of Silver Nanoparticles/Functionalized Multi-Walled Carbon Nanotubes As an Amperometric Sensor." Materials Science and Engineering C 66, no. (2016): 77-83.
Harvard	Baghayeri M et al. (2016) 'A Novel Way for Detection of Antiparkinsonism Drug Entacapone Via Electrodeposition of Silver Nanoparticles/Functionalized Multi-Walled Carbon Nanotubes As an Amperometric Sensor', Materials Science and Engineering C, 66(), pp. 77-83.
Vancouver	Baghayeri M, Tehrani MB, Amiri A, Maleki B, Farhadi S. A Novel Way for Detection of Antiparkinsonism Drug Entacapone Via Electrodeposition of Silver Nanoparticles/Functionalized Multi-Walled Carbon Nanotubes As an Amperometric Sensor. Materials Science and Engineering C. 2016;66():77-83.
BibTex	@article{ author = {Baghayeri M and Tehrani MB and Amiri A and Maleki B and Farhadi S}, title = {A Novel Way for Detection of Antiparkinsonism Drug Entacapone Via Electrodeposition of Silver Nanoparticles/Functionalized Multi-Walled Carbon Nanotubes As an Amperometric Sensor}, journal = {Materials Science and Engineering C}, volume = {66}, number = {}, pages = {77-83}, year = {2016} }
RIS	TY - JOUR AU - Baghayeri M AU - Tehrani MB AU - Amiri A AU - Maleki B AU - Farhadi S TI - A Novel Way for Detection of Antiparkinsonism Drug Entacapone Via Electrodeposition of Silver Nanoparticles/Functionalized Multi-Walled Carbon Nanotubes As an Amperometric Sensor JO - Materials Science and Engineering C VL - 66 IS - SP - 77 EP - 83 PY - 2016 ER -

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