Short Term Exercise Training Enhances Cell-Mediated Responses to Hsv-1 Vaccine in Mice

Short Term Exercise Training Enhances Cell-Mediated Responses to Hsv-1 Vaccine in Mice Publisher Pubmed

Molanouri Shamsi M¹ ; Najedi S² ; Hassan ZM³ ; Isanejad A⁴ ; Mahdavi M^{5, 6}

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1. Physical Education & Sport Sciences Dept., Faculty of Humanities, Tarbiat Modares University, Jala Ale Ahmad Exp. Tehran, P.O.Box: 14117-13116, Tehran, Iran
2. Physical Education & Sport Sciences Dept., Faculty of Humanities, Taft Azad University, Iran
3. Department of Immunology, School of Medical Sciences, Tarbiat Modares University, Jala Ale Ahmad Exp. Tehran, P.O.Box: 14115-13116, Tehran, Iran
4. Physical Education & Sport Sciences Dept., Faculty of Humanities, Shahed University, P.O.Box: 14117-13116, Tehran, Iran
5. Immunology Department, Pasteur Institute of Iran, 69 Pasteur Ave, P.O.Box: 13185-1183, Tehran, Iran
6. Recombinant Vaccine Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Microbial Pathogenesis Published:2017

Abstract

Exercise (with appropriate intensity and duration) is a natural modulator of immune responses and may be useful to increase the vaccine response towards antigen. According to the fact that rural area responding butter than urbon area to vaccine protocol, this study was undertaken to test the hypothesis that short term exercise training as an adjuvant for antigen such as herpes simplex virus type 1 (HSV-1) in animal models. Mice with/without access to short term exercise training were immunized intramuscularly with inactivated KOS strain of HSV-1. Immune responses was investigated with regards of both cell-mediated and humoral immunity. In this study by using short term exercise training as an adjuvant enhanced Th1 response while it did not show significant effect on Th2 responses towards HSV-1 immunization. Also, immunoglobulin G (IgG) 2a/IgG1-ratios increased in vaccine with short term exercise training group. These results suggested that coupling short term moderate exercise training as a mild adjuvant with vaccination may enhance cell-mediated immune responses especially Th1 responses. © 2017 Elsevier Ltd

2. Combined Effect of Aerobic Interval Training and Selenium Nanoparticles on Expression of Il-15 and Il-10/Tnf-Α Ratio in Skeletal Muscle of 4T1 Breast Cancer Mice With Cachexia, Cytokine (2017)

3. Evaluation of G2 Citric Acid-Based Dendrimer As an Adjuvant in Veterinary Rabies Vaccine, Viral Immunology (2018)

4. The Immunomodulatory Effects of Fish-Oil Supplementation in Elite Paddlers: A Pilot Randomized Double Blind Placebo-Controlled Trial, Prostaglandins Leukotrienes and Essential Fatty Acids (2015)

5. Physical Activity As a Counteracting Measure to Mitigate the Harmful Effects of Covid-19 Lockdowns: Special Focus on Healthy Children, Adolescents, Adults, Elderly, Athletes, and People With Down Syndrome, Mental Health Effects of COVID-19 (2021)

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Mohammad Hossein Yazdi (2)

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Style	Citing Format
MLA	Molanouri Shamsi M, et al.. "Short Term Exercise Training Enhances Cell-Mediated Responses to Hsv-1 Vaccine in Mice." Microbial Pathogenesis, vol. 110, no. , 2017, pp. 457-463.
APA	Molanouri Shamsi M, Najedi S, Hassan ZM, Isanejad A, Mahdavi M (2017). Short Term Exercise Training Enhances Cell-Mediated Responses to Hsv-1 Vaccine in Mice. Microbial Pathogenesis, 110(), 457-463.
Chicago	Molanouri Shamsi M, Najedi S, Hassan ZM, Isanejad A, Mahdavi M. "Short Term Exercise Training Enhances Cell-Mediated Responses to Hsv-1 Vaccine in Mice." Microbial Pathogenesis 110, no. (2017): 457-463.
Harvard	Molanouri Shamsi M et al. (2017) 'Short Term Exercise Training Enhances Cell-Mediated Responses to Hsv-1 Vaccine in Mice', Microbial Pathogenesis, 110(), pp. 457-463.
Vancouver	Molanouri Shamsi M, Najedi S, Hassan ZM, Isanejad A, Mahdavi M. Short Term Exercise Training Enhances Cell-Mediated Responses to Hsv-1 Vaccine in Mice. Microbial Pathogenesis. 2017;110():457-463.
BibTex	@article{ author = {Molanouri Shamsi M and Najedi S and Hassan ZM and Isanejad A and Mahdavi M}, title = {Short Term Exercise Training Enhances Cell-Mediated Responses to Hsv-1 Vaccine in Mice}, journal = {Microbial Pathogenesis}, volume = {110}, number = {}, pages = {457-463}, year = {2017} }
RIS	TY - JOUR AU - Molanouri Shamsi M AU - Najedi S AU - Hassan ZM AU - Isanejad A AU - Mahdavi M TI - Short Term Exercise Training Enhances Cell-Mediated Responses to Hsv-1 Vaccine in Mice JO - Microbial Pathogenesis VL - 110 IS - SP - 457 EP - 463 PY - 2017 ER -

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