Tehran University of Medical Sciences

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Genetic and Cellular Complexity of Brain Tumors Publisher



Karami F1 ; Mehdipour P2
Authors

Source: Cancer Genetics and Psychotherapy Published:2017


Abstract

Brain tumors are associated with high mortality rate and considered as a leading cause of death among the human cancers. The main molecular mechanisms behind the pathophysiology of brain tumors could be summarized in three major classifications including aberrant signaling pathways, genetic mutations, polymorphisms and epigenetic alterations. Personalized treatment of brain tumor patients based on the specific molecular changes can increase the overall survival of affected individuals. Beside approved different chemotherapy and radiotherapy approaches, psychotherapy can enhance the life expectancy of patients and temporarily increase the success rate of moderating the disease progression. © Springer International Publishing AG 2017. All rights reserved.
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