Synthesis, Characterization, and Toxicity of Multi-Walled Carbon Nanotubes Functionalized With 4-Hydroxyquinazoline

Synthesis, Characterization, and Toxicity of Multi-Walled Carbon Nanotubes Functionalized With 4-Hydroxyquinazoline Publisher

Tahermansouri H¹ ; Mirosanloo A¹ ; Keshel SH² ; Gardaneh M³

Show Affiliations

1. Department of Chemistry, Ayatollah Amoli Branch, Islamic Azad University, Amol, 678, Iran
2. Stem Cell Preparation Unit, Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, 1336616351, Iran
3. National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, 14965/161, Iran

Source: Carbon Letters Published:2016

Abstract

The attachment of 2-aminobenzamide to carboxylated multi-wall carbon nanotubes (MWCNTs)- COOH was achieved through the formation of amide bonds. Then, the functionalized MWCNTs, MWCNT-amide, were treated by phosphoryl chloride to produce MWCNT-quin. The products were characterized by Fourier transform infrared spectroscopy, Raman spectroscopy, scanning electron microscopy, thermogravimetric analysis, derivative thermogravimetric, steady-state fluorescence spectroscopy, and solubility testing. MWCNT-quin showed photo-electronic properties, which is due to the attachment of the 4-hydroxyquinazoline groups to them as proved by steady-state fluorescence spectroscopy. This suggests intramolecular interactions between the tubes and the attached 4-hydroxyquinazoline. The toxicity of the samples was evaluated in human embryonic kidney HEK293 and human breast cancer SKBR3 cell lines, and the viable cell numbers were measured by 3-(4,5-dimethyl- 2-thiazolyl)-2,5-diphenyltetrazolium bromide (MTT) after the cells were cultured for 24 h. Cellular investigations showed that the modified MWCNTs, particularly MWCNT-quin, have considerably significant toxic impact on SKBR3 as compared to HEK293 at the concentration of 5 μg/mL. © Korean Carbon Society.

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Experts (# of related papers)

Mehdi Norouzi (1)

Style	Citing Format
MLA	Tahermansouri H, et al.. "Synthesis, Characterization, and Toxicity of Multi-Walled Carbon Nanotubes Functionalized With 4-Hydroxyquinazoline." Carbon Letters, vol. 17, no. 1, 2016, pp. 45-52.
APA	Tahermansouri H, Mirosanloo A, Keshel SH, Gardaneh M (2016). Synthesis, Characterization, and Toxicity of Multi-Walled Carbon Nanotubes Functionalized With 4-Hydroxyquinazoline. Carbon Letters, 17(1), 45-52.
Chicago	Tahermansouri H, Mirosanloo A, Keshel SH, Gardaneh M. "Synthesis, Characterization, and Toxicity of Multi-Walled Carbon Nanotubes Functionalized With 4-Hydroxyquinazoline." Carbon Letters 17, no. 1 (2016): 45-52.
Harvard	Tahermansouri H et al. (2016) 'Synthesis, Characterization, and Toxicity of Multi-Walled Carbon Nanotubes Functionalized With 4-Hydroxyquinazoline', Carbon Letters, 17(1), pp. 45-52.
Vancouver	Tahermansouri H, Mirosanloo A, Keshel SH, Gardaneh M. Synthesis, Characterization, and Toxicity of Multi-Walled Carbon Nanotubes Functionalized With 4-Hydroxyquinazoline. Carbon Letters. 2016;17(1):45-52.
BibTex	@article{ author = {Tahermansouri H and Mirosanloo A and Keshel SH and Gardaneh M}, title = {Synthesis, Characterization, and Toxicity of Multi-Walled Carbon Nanotubes Functionalized With 4-Hydroxyquinazoline}, journal = {Carbon Letters}, volume = {17}, number = {1}, pages = {45-52}, year = {2016} }
RIS	TY - JOUR AU - Tahermansouri H AU - Mirosanloo A AU - Keshel SH AU - Gardaneh M TI - Synthesis, Characterization, and Toxicity of Multi-Walled Carbon Nanotubes Functionalized With 4-Hydroxyquinazoline JO - Carbon Letters VL - 17 IS - 1 SP - 45 EP - 52 PY - 2016 ER -

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