Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
An Insight Into the Toxicological Impacts of Carbon Nanotubes (Cnts) on Human Health: A Review Publisher



Awasthi S1 ; Srivastava A2 ; Kumar D3 ; Pandey SK4 ; Mubarak NM5, 6, 7 ; Dehghani MH8, 9 ; Ansari K10
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Chemistry, Manipal University, Jaipur, 303007, India
  2. 2. Department of Mechanical Engineering, Manipal University, Jaipur, 303007, India
  3. 3. Department of Chemistry, School of Chemical Engineering and Physical Sciences, Lovely Professional University, Punjab, Phagwara, 144411, India
  4. 4. Department of Chemistry, Maulana Azad National Institute of Technology, Bhopal, 462003, India
  5. 5. Petroleum and Chemical Engineering, Faculty of Engineering, Universiti Teknologi Brunei, Bandar Seri Begawan, BE1410, Brunei Darussalam
  6. 6. Department of Biosciences, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, Chennai, India
  7. 7. Centre for Research Impact & Outcome, Chitkara University Institute of Engineering and Technology, Chitkara University, Punjab, Rajpura, 140401, India
  8. 8. Department of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  9. 9. Center for Solid Waste Research, Institute for Environmental Research, Tehran University of Medical Sciences, Tehran, Iran
  10. 10. Department of Civil Engineering, Yeshwantrao Chavan College of Engineering, Maharashtra, Nagpur, 441110, India

Source: Environmental Advances Published:2024


Abstract

Carbon nanotubes (CNTs) have gained significant attention due to their unique mechanical, electrical, and thermal properties. These exciting properties of CNTs make them productive in various applications, from electronics to optics to therapeutics. However, concerns about the potential toxicity of carbon nanotubes have also been raised, prompting extensive research to understand their effects on human health and the environment. Several studies have investigated the toxicity of carbon nanotubes, and the results vary depending on factors such as size, shape, surface chemistry, and the route of exposure. This review highlights the toxicological aspects of CNTs with a special focus on the major consequences of CNT toxicity. The study unfolds the prospects on how the toxicity of CNTs causes adverse effects on the central nervous system, kidney, spleen, eye, cardiac, etc., and thus can influence numerous applications covering from clinical to environmental. Moreover, the report offers an imperative deliberation over the curing or remedies of CNT toxicity, which can provide collective insights for the researchers. Thus, this review report provides the developments, implications, and different approaches to CNT toxicity so that the readers can clearly understand the wide-ranging forecasts of CNT toxicity. © 2024
Related Docs
View other Related Docs
1. The Toxicity and Therapeutic Effects of Single-And Multi-Wall Carbon Nanotubes on Mice Breast Cancer, Scientific Reports (2018)
2. Carbon Nanotubes: Smart Drug/Gene Delivery Carriers, International Journal of Nanomedicine (2021)
3. Health Concerns of Various Nanoparticles: A Review of Their in Vitro and in Vivo Toxicity, Nanomaterials (2018)
4. The Role of Single- and Multi-Walled Carbon Nanotube in Breast Cancer Treatment, Therapeutic Delivery (2020)
5. Carbon Nanotubes Part Ii: A Remarkable Carrier for Drug and Gene Delivery, Expert Opinion on Drug Delivery (2015)
6. Biological Response to Carbon-Family Nanomaterials: Interactions at the Nano-Bio Interface, Frontiers in Bioengineering and Biotechnology (2019)
7. Application of Carbon Nanotubes in Nanomedicine: New Medical Approach for Tomorrow, Medical Imaging: Concepts# Methodologies# Tools# and Applications (2016)
8. Multifunctional Carbon-Based Nanoparticles: Theranostic Applications in Cancer Therapy and Diagnosis, ACS Applied Bio Materials (2023)
Experts (# of related papers)
View all Related Experts
Fatemeh Atyabi (3)
Alimohammad Alizadeh (2)
Other Related Docs
9. The Effect of Fibronectin on Structural and Biological Properties of Single Walled Carbon Nanotube, Applied Surface Science (2015)
10. Recent Advances on Hyperthermia Therapy Applications of Carbon-Based Nanocomposites, Colloids and Surfaces B: Biointerfaces (2023)
11. Toxicity of Nanoparticles and an Overview of Current Experimental Models, Iranian Biomedical Journal (2016)
12. Carbon Nanotubes in Microfluidic Lab-On-A-Chip Technology: Current Trends and Future Perspectives, Microfluidics and Nanofluidics (2017)
13. Synthesis and Evaluation of Multi-Wall Carbon Nanotube-Paclitaxel Complex As an Anti-Cancer Agent, Gastroenterology and Hepatology from Bed to Bench (2016)
14. Necrotic, Apoptotic and Autophagic Cell Fates Triggered by Nanoparticles, Autophagy (2019)
15. Targeted Cancer Therapy Through Antibody Fragments-Decorated Nanomedicines, Journal of Controlled Release (2017)
16. Emerging Novel Approaches for the Enhanced Delivery of Natural Products for the Management of Neurodegenerative Diseases, Journal of Molecular Neuroscience (2022)
17. Carbon Nanotubes Part I: Preparation of a Novel and Versatile Drug-Delivery Vehicle, Expert Opinion on Drug Delivery (2015)
18. Regulation of Stem Cell Fate by Nanomaterial Substrates, Nanomedicine (2015)
19. Interaction of Single and Multi Wall Carbon Nanotubes With the Biological Systems: Tau Protein and Pc12 Cells As Targets, Scientific Reports (2016)
20. Nanotechnology-Assisted Lung Cancer Diagnosis: Biomarkers and Imaging, Journal of Nanoparticle Research (2025)
21. Curcumin and Its Novel Formulations for the Treatment of Hepatocellular Carcinoma: New Trends and Future Perspectives in Cancer Therapy, Journal of Functional Foods (2023)
22. Toxicity of Inorganic Nanoparticles, Comprehensive Analytical Chemistry (2022)
23. In Vivo Drug Delivery of Gemcitabine With Pegylated Single-Walled Carbon Nanotubes, Materials Science and Engineering C (2016)
24. Occupational Exposure to Nanomaterials: Hazards, Toxicity and Safety Concerns, Nanomaterials in Industrial Chemistry (2024)
25. Advanced Bioengineering of Male Germ Stem Cells to Preserve Fertility, Journal of Tissue Engineering (2021)
26. Influence of Peg Molecular Weight on the Drug Release and in Vitro Cytotoxicity of Single-Walled Carbon Nanotubes-Peg-Gemcitabine Conjugates, Current Drug Delivery (2016)
27. Effects of Prenatal Exposure to Single-Wall Carbon Nanotubes on Reproductive Performance and Neurodevelopment in Mice, Toxicology and Industrial Health (2016)