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Synthesis of Fe5c2@Sio2 Core@Shell Nanoparticles As a Potential Candidate for Biomedical Application Publisher



Ahmadpoor F1 ; Shojaosadati SA2 ; Delavari HH1 ; Christiansen G3 ; Saber R4
Authors
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Authors Affiliations
  1. 1. Department of Materials Engineering, Tarbiat Modares University, PO Box 14115-143, Tehran, Iran
  2. 2. Biotechnology Group, Faculty of Chemical Engineering, Tarbiat Modares University, PO Box 14115-143, Tehran, Iran
  3. 3. Department of Biomedicine-Medical Microbiology and Immunology, Aarhus University, Aarhus C, 8000, Denmark
  4. 4. Department of Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, 1417614411, Iran

Source: Materials Research Express Published:2018


Abstract

A new strategy for water-dispersibility of hydrophobic carbide nanostructures was proposed. In this regard, hydrophobic Fe5C2 nanoparticles (NPs) with size ranging 25-40 nm were synthesized and coated with 12-15 nm silica shell for biomedical applications. X-ray diffraction (XRD) results revealed that Fe5C2 NPs with monoclinic structure were successfully prepared. The crystalline structure of Fe5C2 NPs was remained unchanged and saturation magnetization of core remained nearly constant after coating with silica shell. Moreover, Raman spectroscopy identified D-band of amorphous carbon shells which was also confirmed by transmission electron microscopy (TEM). Finally, Fe5C2@SiO2 core@shell NPs demonstrated no significant cytotoxicity and appropriate heat generating which makes them a promising candidate for magnetic fluid hyperthermia applications. © 2018 IOP Publishing Ltd.