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Silk As a Promising Biomaterial for 3D Bioprinting: A Comprehensive Review of Bombyx Mori Silk’S Biomedical Applications Publisher



Khosropanah MH1, 2 ; Rajabi M3 ; Behboodi Tanourlouee S1 ; Azimzadeh A1 ; Alizadeh Vaghasloo M2, 4 ; Hassannejad Z1
Authors
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Authors Affiliations
  1. 1. Pediatric Urology and Regenerative Medicine Research Center, Gene, Cell and Tissue Research Institute, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Traditional Medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Centre for Bioengineering & Nanomedicine, Faculty of Dentistry, Division of Health Sciences, University of Otago, Dunedin, New Zealand
  4. 4. Persian Medicine Network (PMN), Universal Scientific Education and Research Network (USERN), Tehran, Iran

Source: International Journal of Polymeric Materials and Polymeric Biomaterials Published:2024


Abstract

This comprehensive review discusses the exceptional mechanical and biological properties of the Bombyx mori silkworm’s silk fibroin (SF) and its potential for biomedical applications. It focuses on the recent interest in using SF in 3D bioprinting for tissue engineering and provides an overview of advancements in this area. The review covers topics such as fabrication techniques, properties of SF-based bioinks, scaffold design, and applications in tissue engineering fields like bone, cartilage, skin, nerve, and vascular tissue regeneration. It also addresses future challenges and directions, including improving printing resolution and developing new silk-based biomaterials or their combination with other hydrogels. © 2024 Taylor & Francis Group, LLC.
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