National and Sub-National Burden and Trend of Type 1 Diabetes in 31 Provinces of Iran, 1990–2019 Publisher Pubmed



Bandarian F¹ ; Sharifnejad Tehrani Y² ; Peimani M³ ; Namazi N⁴ ; Saeedi Moghaddam S^{2, 5} ; Esmaeili S⁶ ; Rashidi MM² ; Nasli Esfahani E⁷ ; Masinaei M² ; Rezaei N² ; Rezaei N² ; Farzadfar F^{2, 8} ; Larijani B⁸
Source: Scientific Reports Published:2023

Abstract

The aim of the study was to report the burden of type one diabetes mellitus (T1DM) by sex, age, year, and province in Iran over the past 30 years, according to data provided by the global burden of disease (GBD) study. Incidence, prevalence, death, disability-adjusted life-years (DALYs), years of life lost, and years lived with disability due to T1DM by age groups and sex was reported for 31 provinces of Iran from 1990 to 2019 with their 95% uncertainty intervals (UI). In 2019, national age-standardized incidence (11.0 (95% UI: 8.9–13.5)), prevalence (388.9 (306.1–482.1)), death (0.7 (0.6–0.8)), and DALYs (51.7 (40.9–65.1)) rates per 100,000 wre higher than 1990 except for death. Also, the mortality to incidence ratio reduced in all provinces over time particularly after 2014 as well. GBD data analysis showed that age-standardized incidence and prevalence rates of T1DM have increased, the death rate reduced, and DALYs remained unchanged during the past 30 years in Iran and its 31 provinces. death rate reduced and DALYs remained unchanged during the past 30 years in Iran and its 31 provinces. © 2023, The Author(s).