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Biosensing Applications of Zno / Graphene on Glassy Carbon Electrode in Analysis of Tyrosine Publisher



Norouzi P1, 2 ; Salimi H3 ; Tajik S4 ; Beitollahi H4 ; Rezapour M5 ; Larijani B6
Authors
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Authors Affiliations
  1. 1. Center of Excellence in Electrochemistry, University of Tehran, Tehran, Iran
  2. 2. Biosensor Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Chemistry, Graduate University of Advanced Technology, Kerman, Iran
  4. 4. Environment Department, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran
  5. 5. IP Department, Research Institute of the Petroleum Industry (RIPI), P.O. Box 14665-137, Tehran, Iran
  6. 6. Diabetes Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: International Journal of Electrochemical Science Published:2017


Abstract

A graphene-zinc oxide (ZnO/GR) nanocomposite film was fabricated on the glassy carbon electrode (ZnO/GR/GCE), and used for the measurement of tyrosine (Tyr) by differential pulse voltammetry (DPV). It was found that the ZnO/GR nanocomposites can improve the peak currents of tyrosine significantly due to the synergetic effect. The oxidation peak current was linearly related to tyrosine concentration in the range from 1.0 μM to 800.0 μM. The detection limit was calculated to be 0.5 μM (S/N = 3). Finally, the introduced electrode was successfully used for quantifying tyrosine in real samples. © 2017 The Authors.