Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Effective Factors in the Survival Time of Covid-19 Patients in Three Epidemic Waves: A Prospective Cohort Study



Kargarianmarvasti S1, 2 ; Malihe Hasannezhad M3 ; Abolghasemi J4
Authors
Show Affiliations
Authors Affiliations
  1. 1. Faculty of Health, Iran University of Medical Sciences, Tehran, Iran
  2. 2. Centers for Disease Control and Prevention, Health Center of Fereydunshahr, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Department of Infectious Diseases, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Biostatistics, School of Public Health, Iran University of Medical Sciences, Tehran, Iran

Source: Iranian Journal of Epidemiology Published:2021

Abstract

Background and Objectives: This study aimed to investigate the effective factors in the survival/hazard time of Covid-19 patients in three waves of epidemic. Methods: All 880 Covid-19 patients were included in this prospective cohort study using the census method. Polymerase chain reaction was used to diagnose Covid-19. The survival status of these patients was followed up for 4 months. The analysis of this study was based on the time of infection in three epidemic waves in IRAN. To analyze the data, the Kaplan-Meier nonparametric approach and Cox proportional hazards regression model were used. Survival distributions were compared in three epidemic waves using the R software (version 3.6.2) (P<0.05). Results: We diagnosed 880 positive case of Covid-19 using PCR test on 2269 susspected people who had respiratory symptomps. At the end of 1-year follow-up, cumulative incidence (risk) of Covid-19 was estimated 7%. Effective factors in the survival time of patients with Covid-19 based on Cox multivariate regression model were: 1-Age 2-Intensity of infection (Hospitalization) 3-Heart disease 4-Epidemic Wave and 5-Transmission mode of the disease (P <0.05). The Kaplan-Meier approach and log rank test (Mantel-Cox) showed a significant difference in the survival rate in three epidemic waves (P = 0.018). Conclusion: Elderly patients, especially those with a history of heart disease, are at higher risk of death than other groups. In addition to regular screening, these patients will need active monitoring, especially at the time of hospitalization. © 2021 The Authors.
Other Related Docs
12. Therapeutic Potentials and Candidates for Covid-19, Iranian Journal of Science (2023)
15. Geriatrics and Covid-19, Advances in Experimental Medicine and Biology (2021)
17. A Reliable Prognostic Marker for Liver Dysfunction in Covid-19 Infection, Middle East Journal of Digestive Diseases (2021)
25. Pharmacological Treatments of Covid-19, Pharmacological Reports (2020)
37. Antiviral Optical Techniques As a Possible Novel Approach to Covid-19 Treatment, Journal of Innovative Optical Health Sciences (2021)