Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Solubilization of Naproxen: Experimental Data and Computational Tools Publisher



Mohammadian E1 ; Jouyban A2, 3 ; Barzegarjalali M4 ; Rahimpour E2, 6
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Pharmaceutical Chemistry, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Pharmaceutical Analysis Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
  3. 3. Kimia Idea Pardaz Azarbayjan (KIPA) Science Based Company, Tabriz University of Medical Sciences, Tabriz, Iran
  4. 4. Research Center for Pharmaceutical Nanotechnology and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
  5. 5. Department of Chemistry, University of North Texas, Denton, 76203-5070, TX, United States
  6. 6. Food and Drug Safety Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

Source: Journal of Molecular Liquids Published:2019


Abstract

A number of trained models based on the Jouyban-Acree model were proposed for prediction of naproxen (NAP) solubility in the cosolvency systems. The predictive cosolvency models were obtained by the combination of the Jouyban-Acree model with variables derived from the Abraham solvation parameters and the Hansen solubility parameters. The applicability of the proposed methods was evaluated by calculating the overall mean relative deviation (MRD%) values of the solubility data for NAP in 11 cosolvency systems and discussed. The proposed models enable the researchers to predict the solubility behavior of NAP in various solvent mixtures at different temperatures that can be helpful in the pharmaceutical industry. © 2019 Elsevier B.V.
Related Docs
View other Related Docs
1. Simulation of Mesalazine Solubility in the Binary Solvents at Various Temperatures, Journal of Molecular Liquids (2022)
2. Computational Tools for Solubility Prediction of Celecoxib in the Binary Solvent Systems, Journal of Molecular Liquids (2020)
3. Trained Models for Solubility Prediction of Drugs in Acetonitrile + Water Mixtures at Various Temperatures, Physics and Chemistry of Liquids (2021)
4. Mesalazine Solubility in the Binary Mixtures of Ethanol and Water at Various Temperatures, Physics and Chemistry of Liquids (2021)
5. Comments Concerning “Solvent Effect and Preferential Solvation of Cefpiramide in Cosolvent Plus Water Mixtures”, Journal of Molecular Liquids (2019)
6. Mesalazine Solubility in Propylene Glycol and Water Mixtures at Various Temperatures Using a Laser Monitoring Technique, Journal of Molecular Liquids (2020)
7. Solubility of Mesalazine in {Acetonitrile + Water} Mixtures at Various Temperatures, Physics and Chemistry of Liquids (2021)
8. Solubility of Caffeine in Carbitol + Ethanol Mixture at Different Temperatures, Journal of Molecular Liquids (2020)
Experts (# of related papers)
Alireza Foroumadi (1)
Other Related Docs
9. Solubility of Sildenafil Citrate in the Binary Mixtures of Ethylene Glycol and Water at Different Temperatures, Journal of Molecular Liquids (2020)
10. Solubility of Codeine Phosphate in Carbitol + 2-Propanol Mixture at Different Temperatures, Drug Development and Industrial Pharmacy (2020)
11. Solubilisation of Dexamethasone: Experimental Data, Co-Solvency and Polarised Continuum Modelling, Physics and Chemistry of Liquids (2021)
12. A Laser Monitoring Technique for Determination of Mesalazine Solubility in Propylene Glycol and Ethanol Mixtures at Various Temperatures, Journal of Molecular Liquids (2020)
13. Further Comments on “Experimental Measurements, Equilibrium Study and Model Correlation of Methyl Paraben in Ethanol and Methanol Aqueous Solutions From = (293.15 to 323.15) K”, Journal of Molecular Liquids (2020)
14. Solubilization of Bosentan Using Ethanol As a Pharmaceutical Cosolvent, Journal of Molecular Liquids (2017)
15. Solubility of Meloxicam in (Carbitol® + Water) Mixtures: Determination, Correlation, Dissolution Thermodynamics and Preferential Solvation, Journal of Molecular Liquids (2021)
16. Solubility and Thermodynamic Properties of Mesalazine in {2-Propanol + Water} Mixtures at Various Temperatures, Journal of Molecular Liquids (2020)
17. The Solubility of Ketoconazole in Binary Carbitol + Water Mixtures at T = (293.2–313.2) K, Journal of Molecular Liquids (2020)
18. Solubility of Mesalazine in {1-Propanol/Water} Mixtures at Different Temperatures, Journal of Molecular Liquids (2020)
19. Measurement and Modelling of the Solubility for Ketoconazole in {Acetonitrile + Water} Mixtures at T = (293.2 to 313.2) K, Physics and Chemistry of Liquids (2021)
20. Solubility of Codeine Phosphate in N-Methyl-2-Pyrrolidone +2-Propanol Mixture at Different Temperatures, Journal of Molecular Liquids (2020)
21. Predicting the Solubility, Thermodynamic Properties and Preferential Solvation of Sulphamethazine in {Acetonitrile + Water} Mixtures Using a Minimum Number of Experimental Data Points, Physics and Chemistry of Liquids (2021)
22. Further Numerical Analyses on the Solubility of Diazepam in Aqueous Tert-Butanol Mixtures, Physics and Chemistry of Liquids (2021)
23. Solubility of Ketoconazole in 1,4-Dioxane + Water Mixtures at T = (293.2 to 313.2) K, Journal of Molecular Liquids (2020)
24. Solubility of Caffeine in N-Methyl-2-Pyrrolidone + Ethanol Mixture at Different Temperatures, Journal of Molecular Liquids (2020)
25. Solubility of Mesalazine in Polyethylene Glycol 400 + Water Mixtures at Different Temperatures, Journal of Molecular Liquids (2020)