Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Comparison of Ovarian Morphology, Pattern of Menstrual Cycles, and Testosterone Level in Polycystic Ovary Syndrome Patients Regarding Body Mass Index Value



Mardanian F1 ; Moradi M2
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Obstetrics and Gynecology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Intern, Department of Obstetrics and Gynecology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Isfahan Medical School Published:2009

Abstract

Background: Considering the heterogenicity of polycystic ovary syndrome (PCOS), the diagnosis is difficult. The aim of present study was to compare ovarian morphology, pattern of menstrual cycles and testosterone level in obese and non obese polycystic ovary syndromepatients. Methods: Clinical characteristics, hormonal profile and ovarian morphology were evaluated in 54 women with polycystic ovary syndrome, aged 21-48 years. They were devided in 2 groups regarding Body Mass Index; obese (BMI ≥ 25) and nonobese (BMI < 25). Fidings were statistically analyzed. Findings: Mean BMI was 28.5 ± 3.2 in obese group and 21 ± 2.6 kg/m2 in nonobese group. Menstrual cycles were regular in 11 patients (20.4%) and irregular in 43 patients (79.6%). BMI was 23.6 ± 3.6 in patients with regular cycles and 25 ± 5 in those with irregular cycles (P = 0.36). Mean testosterone level was 7.1 ± 1.7 in obese and 5.6 ± 2.9 ng/ml in nonobese group (P = 0.69). In obese group, ovarian morphology was normal in only 8 patients (29.6%) and abnormal in 19 patients (70.4%) (P = 0.039) and in nonobese group 12 patients (44.4%) had normal morphology and 15 patients (55/6%) had abnormal morphology. (P = 0.039). Conclusion: Our study suggests that there is significant correlation between BMI and ovarian morphology but there is no significant difference between BMI and menstrual cycle or BMI and testosterone level. Thus both obese and nonobse PCOS patients show different presentations and it is necessary to do more studies to compare clinical features of PCOS in obese and nonobese patients for early diagnosis and management. © 2009, Isfahan University of Medical Sciences(IUMS). All rights reserved.
Related Docs
View other Related Docs
1. Prevalence of Polycystic Ovary Syndrome in Reproductive-Aged Women With Type 2 Diabetes, Gynecological Endocrinology (2008)
2. Prevalence of Polycystic Ovary Syndrome in Girls Aged 14-18 Years in Isfahan, Iran, Hormone Research (2004)
3. The Prevalence of Metabolic Syndrome and Insulin Resistance According to the Phenotypic Subgroups of Polycystic Ovary Syndrome in a Representative Sample of Iranian Females, Journal of Research in Medical Sciences (2011)
4. The Prevalence of Polycystic Ovary Syndrome in Iranian Women Based on Different Diagnostic Criteria, Endokrynologia Polska (2011)
5. Diagnostic Value of Prostate-Specific Antigen in Women With Polycystic Ovary Syndrome, Journal of Research in Medical Sciences (2011)
6. The Prevalence of Polycystic Ovary Syndrome (Pcos) in Type 2 Diabetic Women in Reprodutive Ages, Iranian Journal of Diabetes and Lipid Disorders (2006)
7. The Diagnostic Value of Anti-Mullerian Hormone Marker in Predicting Response to Treatment of Infertility in Patients With Polycystic Ovary Syndrome, Journal of Isfahan Medical School (2016)
8. New Insights Into the Relationship of Antimullerian Hormone With Polycystic Ovary Syndrome and Its Diagnostic Accuracy: An Updated and Extended Meta-Analysis Using a Marginal Beta-Binomial Model, American Journal of Obstetrics and Gynecology (2025)
Experts (# of related papers)
View all Related Experts
Ferdous Mehrabian (11)
Hatav GhasemiTehrani (10)
Other Related Docs
9. Association Between Major Dietary Patterns and Polycystic Ovary Syndrome: Evidence From a Case-Control Study, Applied Physiology, Nutrition and Metabolism (2019)
10. Association Between the Food Security Status and Dietary Patterns With Polycystic Ovary Syndrome (Pcos) in Overweight and Obese Iranian Women: A Case-Control Study, Journal of Ovarian Research (2021)
11. Serum Prostate-Specific Antigen Level in Women With Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis, Hormone and Metabolic Research (2019)
12. Evaluation of Serum Prolactin Levels in Patients With Polycystic Ovary Syndrome, Journal of Isfahan Medical School (2012)
13. Global Prevalence of Polycystic Ovary Syndrome in Women Worldwide: A Comprehensive Systematic Review and Meta-Analysis, Archives of Gynecology and Obstetrics (2024)
14. The Association Between Anthropometric Parameters and Cardiovascular Risk Indicators in Women With Polycystic Ovarian Syndrome, ARYA Atherosclerosis (2020)
15. Omega-3 Supplementation Effects on Polycystic Ovary Syndrome Symptoms and Metabolic Syndrome, Journal of Research in Medical Sciences (2017)
16. Comparison of the Metabolic Parameters and Androgen Level of Umbilical Cord Blood in Newborns of Mothers With Polycystic Ovary Syndrome and Controls, Journal of Research in Medical Sciences (2012)
17. Evaluation of Changes in Levels of Hyperandrogenism, Hirsutism and Menstrual Regulation After a Period of Aquatic High Intensity Interval Training in Women With Polycystic Ovary Syndrome, International Journal of Preventive Medicine (2019)
18. The Effects of Curcumin Supplementation on Glycemic Status, Lipid Profile and Hs-Crp Levels in Overweight/Obese Women With Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial, Complementary Therapies in Medicine (2019)
19. The Effect of Synbiotics Supplementation on Anthropometric Indicators and Lipid Profiles in Women With Polycystic Ovary Syndrome: A Randomized Controlled Trial, Lipids in Health and Disease (2020)
20. Effect of Metformin on Serum Ferritin Level in Women With Polycystic Ovary Syndrome, Iranian Red Crescent Medical Journal (2011)
21. The Effects of Canola and Olive Oils Consumption Compared to Sunflower Oil, on Lipid Profile and Hepatic Steatosis in Women With Polycystic Ovarian Syndrome: A Randomized Controlled Trial, Lipids in Health and Disease (2021)
22. Effect of Auriculotherapy on Menstrual Irregularities in Single Girls With Polycystic Ovarian Syndrome and Aged 18-35 Years in Isfahan in 2012, Iranian Journal of Nursing and Midwifery Research (2015)
23. Can Sex-Hormone Binding Globulin Considered As a Predictor of Response to Pharmacological Treatment in Women With Polycystic Ovary Syndrome?, International Journal of Preventive Medicine (2013)
24. Metformin-Therapy Effects in 50 Clomiphene Citrate Resistant Pcos Patients, Journal of Medical Sciences (2006)
25. The Relationship Between Intake of Dairy Products and Polycystic Ovary Syndrome in Women Who Referred to Isfahan University of Medical Science Clinics in 2013, International Journal of Preventive Medicine (2014)
26. Circulating Resistin and Follistatin Levels in Obese and Non-Obese Women With Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis, PLoS ONE (2021)
27. The Effect of Concentrated Pomegranate Juice on Biomarkers of Inflammation, Oxidative Stress, and Sex Hormones in Overweight and Obese Women With Polycystic Ovary Syndrome: A Randomized Controlled Trial, Phytotherapy Research (2023)
28. Does Carotid Intima-Media Thickness Have Relationship With Polycystic Ovary Syndrome?, International Journal of Preventive Medicine (2013)
29. Comparison of Vitamin D Deficiency in Women With Polycystic Ovary Syndrome Who Referred to Infertility Clinic With Control Group, Journal of Isfahan Medical School (2016)
30. Cardiometabolic Risk Factors in Polycystic Ovary Syndrome, Pakistan Journal of Medical Sciences (2012)
31. Inulin-Type Fructans With Different Degrees of Polymerization Improve Insulin Resistance, Metabolic Parameters, and Hormonal Status in Overweight and Obese Women With Polycystic Ovary Syndrome: A Randomized Double-Blind, Placebo-Controlled Clinical Trial, Food Science and Nutrition (2024)
32. Effects of Probiotic Supplementation on Hormonal and Clinical Outcomes of Women Diagnosed With Polycystic Ovary Syndrome: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial, Journal of Functional Foods (2022)
33. The Effects of Zinc Methionine on Reproductive and Thyroid Hormones in Rats With Polycystic Ovarian Syndrome, Advanced Biomedical Research (2020)
34. Psychological Experiences in Women With Polycystic Ovary Syndrome: A Qualitative Study, Iranian Journal of Nursing and Midwifery Research (2023)
35. Androgen Receptor-Reduced Sensitivity Is Associated With Increased Mortality and Poorer Glycaemia in Men With Type 2 Diabetes Mellitus: A Prospective Cohort Study, Cardiovascular Endocrinology and Metabolism (2020)
36. The Effect of Garlic (Allium Sativum) Supplementation on the Lipid Parameters and Blood Pressure Levels in Women With Polycystic Ovary Syndrome: A Randomized Controlled Trial, Phytotherapy Research (2021)
37. Clinical and Metabolic Responses to Magnesium Supplementation in Women With Polycystic Ovary Syndrome, Biological Trace Element Research (2020)
38. Effect of Probiotics and Synbiotics on Selected Anthropometric and Biochemical Measures in Women With Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis, European Journal of Clinical Nutrition (2020)
39. Increased Insulin Sensitivity by Metformin Enhances Intense-Pulsed-Light- Assisted Hair Removal in Patients With Polycystic Ovary Syndrome, Dermatology (2009)
40. Comparison of the Effects of Metformin, Flutamide Plus Oral Contraceptives, and Simvastatin on the Metabolic Consequences of Polycystic Ovary Syndrome, Journal of Research in Medical Sciences (2016)
41. Calcium Plus Vitamin D Supplementation Influences Biomarkers of Inflammation and Oxidative Stress in Overweight and Vitamin D-Deficient Women With Polycystic Ovary Syndrome: A Randomized Double-Blind Placebo-Controlled Clinical Trial, Clinical Endocrinology (2015)
42. The Effect of Concentrated Pomegranate Juice Consumption on Risk Factors of Cardiovascular Diseases in Women With Polycystic Ovary Syndrome: A Randomized Controlled Trial, Phytotherapy Research (2021)
43. Zinc Status and Polycystic Ovarian Syndrome: A Systematic Review and Meta-Analysis, Journal of Trace Elements in Medicine and Biology (2019)
44. The Association Between Dietary Antioxidants, Oxidative Stress Markers, Abdominal Obesity and Poly-Cystic Ovary Syndrome: A Case Control Study, Journal of Obstetrics and Gynaecology (2020)
45. Associations Between Serum Magnesium Concentrations and Polycystic Ovary Syndrome Status: A Systematic Review and Meta-Analysis, Biological Trace Element Research (2021)
46. Chromium Supplementation and Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis, Journal of Trace Elements in Medicine and Biology (2017)
47. Effect of Using 5A’S Model for Lifestyle Counseling on Psychological Symptoms in Women With Polycystic Ovary Syndrome: A Randomized Field Trial, Scientific Reports (2022)
48. The Effect of N-3 Polyunsaturated Fatty Acid Supplementation on Androgen Status in Patients With Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Clinical Trials, Hormone and Metabolic Research (2016)
49. Effects of Probiotic Supplementation on Pancreatic Β‑Cell Function and C‑Reactive Protein in Women With Polycystic Ovary Syndrome: A Randomized Double‑Blind Placebo‑Controlled Clinical Trial, International Journal of Preventive Medicine (2015)
50. Evaluation of the Effect of Letrozole in the Ovarian Hyperstimulation Syndrome Prevention in Participants at Risk of Treatment With Ovulation-Stimulating Drugs: A Randomized Controlled Trial, Reports of Biochemistry and Molecular Biology (2022)