The Prevalence of Polycystic Ovary Syndrome (Pcos) in Type 2 Diabetic Women in Reprodutive Ages



Horri N^{1, 2} ; Farmani M¹ ; Haghighi S¹ ; Sattari G¹ ; Pournaghshband Z¹ ; Amini M¹ Show Affiliations
Source: Iranian Journal of Diabetes and Lipid Disorders Published:2006

Abstract

Background: Women with polycystic overy syndrome (PCOS) are sussceptible for developing type 2 diabetes (T2DM) and cardiovascular diseases. In view increased prevalence of T2DM in patients with PCOS and priority of prescription agents capable to decrease insulin resistances for them. It is important to diagnose PCOS in T2DM patients. The aim of this study was to evaluate the prevalence of PCOS in T2DM women. Methods: Using '1990 National Institute of Child Health and Human Development Conference of PCOS' criteria, 157 premenopausal women with T2DM were assigned into PCOS and non-PCOS groups after they were examined for the evidences of clinical PCOS. A questionnaire on reproductive history was completed and the waist circumference, weight, height and BP were measured for each participant. Biochemical tests were performed in both groups, but hormonal measurements were requested only for PCOS group. Results: The prevalence of PCOS was high (about 8%) among subjects. Patients with PCOS had significantly lower age at the onset of diabetes, higher BMI and waist circumference. The differences in BP, serum TG, HDL, LDL, cholesterol and HbA1c were non-significant between 2 groups and insulin resistance is more. Conclusion: PCOS is prevalent in diabetic women and Insulin resistance is more likely in those with both PCOS and T2DM resistant than whom with diabetes alone. Emphasis on reducing insulin resistance may be of benefit to achieve a better diabetes control in these patients.