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Multifunctional Plant Virus Nanoparticles for Targeting Breast Cancer Tumors Publisher



Shahgolzari M1 ; Dianatmoghadam H2 ; Yavari A3 ; Fiering SN4, 5 ; Hefferon K6
Authors

Source: Vaccines Published:2022


Abstract

Breast cancer treatment using plant-virus-based nanoparticles (PVNPs) has achieved considerable success in preclinical studies. PVNP-based breast cancer therapies include non-targeted and targeted nanoplatforms for delivery of anticancer therapeutic chemo and immune agents and cancer vaccines for activation of local and systemic antitumor immunity. Interestingly, PVNP platforms combined with other tumor immunotherapeutic options and other modalities of oncotherapy can improve tumor efficacy treatment. These applications can be achieved by encapsulation of a wide range of active ingredients and conjugating ligands for targeting immune and tumor cells. This review presents the current breast cancer treatments based on PVNP platforms. © 2022 by the authors.
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