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Antifungal Cinnamic Acid Derivatives From Persian Leek (Allium Ampeloprasum Subsp. Persicum) Publisher



Sadeghi M1 ; Zolfaghari B1 ; Senatore M2 ; Lanzotti V2
Authors
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Authors Affiliations
  1. 1. Department of Pharmacognosy, Isfahan University of Medical Sciences, 73461 Isfahan, Hezar Jerib Avenue, Iran
  2. 2. Dipartimento di Agraria, Universita Degli Studi di Napoli Federico II, 80055 Portici Napoli, via Universita 100, Italy

Source: Phytochemistry Letters Published:2013


Abstract

A cinnamic imidate, (1Z,2E)-methyl 3-(-p-hydroxy-m-methoxyphenyl)-N-(-p- hydroxyphenethyl) acrylimidate, named persicoimidate (1), has been isolated and characterized from bulbs and seeds of Persian leek, Allium ampeloprasum Subsp. Persicum. Two cinnamic acid derivatives, N-feruloyl tyramine (2) and N-caffeoyl tyramine (3) were isolated from bulbs and seeds. Compound 2 has been previously reported from garlic and leek, while compound 3 is described in Allium plants for the first time. The chemical structures of the isolated compounds have been elucidated unambiguously by spectroscopic methods, including 2D NMR and MS. The isolated compounds were evaluated for their antifungal activity against four fungal pathogens, the soil-borne pathogen Penicillium italicum, the air-borne pathogens Aspergillus niger and Botrytis cinerea, and the antagonistic fungi Trichoderma harzianum to evaluate the possible involvement of such compounds in resistance to pathogen attack. © 2013 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
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