Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Pharmacotherapeutic Potential of Vitis Vinifera (Grape) in Age-Related Neurological Diseases; [Potencial Farmacoterapeutico De Vitis Vinifera (Uva) En Enfermedades Neurologicas Asociadas a La Edad] Publisher



Jadidian F1 ; Amirhosseini M1 ; Abbasi M2 ; Hamedanchi NF3 ; Zerangian N4 ; Erabi G5 ; Abdi A6 ; Hosseini M7 ; Torabi K8 ; Shahini A6 ; Aghakhani A9 ; Norouzkhani N10 ; Kheirandish A11 ; Rashidi S12 Show All Authors
Authors
  1. Jadidian F1
  2. Amirhosseini M1
  3. Abbasi M2
  4. Hamedanchi NF3
  5. Zerangian N4
  6. Erabi G5
  7. Abdi A6
  8. Hosseini M7
  9. Torabi K8
  10. Shahini A6
  11. Aghakhani A9
  12. Norouzkhani N10
  13. Kheirandish A11
  14. Rashidi S12
  15. Deravi N1
  16. Aleebrahimdehkordi E13
Show Affiliations
Authors Affiliations
  1. 1. School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  2. 2. Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  3. 3. Faculty of Medicine, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran
  4. 4. Department of Health Education & Health Promotion, School of Health, Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran
  5. 5. Student Research Committee, Urmia University of Medical Sciences, Urmia, Iran
  6. 6. School of Medicine, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
  7. 7. School of Medicine, Birjand Medical Sciences, Birjand, Iran
  8. 8. School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  9. 9. School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  10. 10. Department of Medical Informatics, Faculty of medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  11. 11. Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran
  12. 12. Mazandaran University of Medical Sciences, Sari, Iran
  13. 13. Shahrekord University of Medical Sciences, Shahrekord, Iran

Source: Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Published:2024


Abstract

Age-related neurological disorders (ANDs), including neurodegenerative diseases, are complex illnesses with an increasing risk with advancing years. The central nervous system's neuropathological conditions, including oxidative stress, neuroinflammation, and protein misfolding, are what define ANDs. Due to the rise in age-dependent prevalence, efforts have been made to combat ANDs. Vitis vinifera has a long history of usage to treat a variety of illness symptoms. Because multiple ligand sites may be targeted, Vitis vinifera components can be employed to treat ANDs. This is demonstrated by the link between the structure and action of these compounds. This review demonstrates that Vitis vinifera and its constituents, including flavonoids, phenolic compounds, stilbenoids and aromatic acids, are effective at reducing the neurological symptoms and pathological conditions of ANDs. This is done by acting as an antioxidant and anti-inflammatory. The active Vitis vinifera ingredients have therapeutic effects on ANDs, as this review explains. © 2024, MS-Editions. All rights reserved.
Related Docs
View other Related Docs
1. Red Grape Juice and Alzheimer's Disease, Diet and Nutrition in Dementia and Cognitive Decline (2015)
2. Role of Bdnf Signaling in the Neuroprotective and Memory-Enhancing Effects of Flavonoids in Alzheimer’S Disease, CNS and Neurological Disorders - Drug Targets (2024)
3. Neuroprotective Effects of Flavonoids, Phytonutrients and Neurological Disorders: Therapeutic and Toxicological Aspects (2023)
4. The Effects of Red Grape Juice and Exercise on Parkinson’S Disease in Male Rats, Journal of Isfahan Medical School (2012)
5. Nutraceuticals for Multiple Sclerosis, Bioactive Nutraceuticals for Brain Disorders (2021)
6. A Review of Plant Extracts and Plant-Derived Natural Compounds in the Prevention/Treatment of Neonatal Hypoxic-Ischemic Brain Injury, International Journal of Molecular Sciences (2021)
7. Therapeutic Potential of Berries in Age-Related Neurological Disorders, Frontiers in Pharmacology (2024)
8. Pharmacotherapeutic Potential of Pomegranate in Age-Related Neurological Disorders, Frontiers in Aging Neuroscience (2022)
Experts (# of related papers)
View all Related Experts
Hojatallah Alaei (2)
Mohammad Bagherniya (1)
Other Related Docs
9. From Kitchen to Clinic: Pharmacotherapeutic Potential of Common Spices in Indian Cooking in Age-Related Neurological Disorders, Frontiers in Pharmacology (2022)