Pharmacotherapeutic Potential of Vitis Vinifera (Grape) in Age-Related Neurological Diseases; [Potencial Farmacoterapeutico De Vitis Vinifera (Uva) En Enfermedades Neurologicas Asociadas a La Edad] Publisher



Jadidian F¹ ; Amirhosseini M¹ ; Abbasi M² ; Hamedanchi NF³ ; Zerangian N⁴ ; Erabi G⁵ ; Abdi A⁶ ; Hosseini M⁷ ; Torabi K⁸ ; Shahini A⁶ ; Aghakhani A⁹ ; Norouzkhani N¹⁰ ; Kheirandish A¹¹ ; Rashidi S¹² Show All Authors
Source: Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Published:2024

Abstract

Age-related neurological disorders (ANDs), including neurodegenerative diseases, are complex illnesses with an increasing risk with advancing years. The central nervous system's neuropathological conditions, including oxidative stress, neuroinflammation, and protein misfolding, are what define ANDs. Due to the rise in age-dependent prevalence, efforts have been made to combat ANDs. Vitis vinifera has a long history of usage to treat a variety of illness symptoms. Because multiple ligand sites may be targeted, Vitis vinifera components can be employed to treat ANDs. This is demonstrated by the link between the structure and action of these compounds. This review demonstrates that Vitis vinifera and its constituents, including flavonoids, phenolic compounds, stilbenoids and aromatic acids, are effective at reducing the neurological symptoms and pathological conditions of ANDs. This is done by acting as an antioxidant and anti-inflammatory. The active Vitis vinifera ingredients have therapeutic effects on ANDs, as this review explains. © 2024, MS-Editions. All rights reserved.