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Barium Carbonate Nanostructures: Biosynthesis and Their Biomedical Applications Publisher



Raessi M1 ; Alijani HQ2 ; Nematollahi FF3 ; Baty RS4 ; Elsaber Batiha G5 ; Khan AU6 ; Hashemi N1 ; Iravani S7 ; Sharifi I8 ; Aflatoonian M8 ; Khatami M1, 8
Authors
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Authors Affiliations
  1. 1. Noncommunicable Diseases Research Center, Bam University of Medical Sciences, Bam, Iran
  2. 2. Department of Biotechnology, Shahid Bahonar University of Kerman, Kerman, Iran
  3. 3. Department of Molecular Biology, Kerman Branch, Islamic Azad University, Kerman, Iran
  4. 4. Department of Biotechnology, College of Science, Taif University, P.O. Box 11099, Taif, 21944, Saudi Arabia
  5. 5. Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour, 22511, AlBeheira, Egypt
  6. 6. Beijing Advanced Innovation Centre for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing, 100029, China
  7. 7. Faculty of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences. Isfahan, Iran
  8. 8. Leishmaniasis Research Center, Kerman University of Medical Sciences, Kerman, Iran

Source: Ceramics International Published:2021


Abstract

In recent years, nanostructures and nanoarchitectures have attracted much attention in the development of biomedicine and nanomedicine. The plant-mediated synthesis of barium carbonate nanoparticles (BACN) has been performed using barium chloride and aqueous extract of natural sweetener (Stevia). In this study, the biosynthesis of BACN has been selected due to the useful medicinal potentials and suitable obtained biocompatibility of produced nanoparticles as well as its simplicity, lesser production steps, and cost-effectiveness. Barium carbonate nanostructures were characterized by X-ray diffraction, scanning electron microscopy, and transmission electron microscope. The toxicity of BACN on U87 brain cancer cells was evaluated based on MTT assay. According to the results, the prepared nanostructures can be employed for biomedical applications, especially cancer therapy. © 2021 Elsevier Ltd and Techna Group S.r.l.
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