Biosynthesis of Spinel Nickel Ferrite Nanowhiskers and Their Biomedical Applications Publisher Pubmed



Alijani HQ^{1, 2} ; Iravani S³ ; Pourseyedi S^{1, 2} ; Torkzadehmahani M⁴ ; Barani M⁵ ; Khatami M^{6, 7, 8} Show Affiliations
Source: Scientific Reports Published:2021

Abstract

Greener methods for the synthesis of various nanostructures with well-organized characteristics and biomedical applicability have demonstrated several advantages, including simplicity, low toxicity, cost-effectiveness, and eco-friendliness. Spinel nickel ferrite (NiFe2O4) nanowhiskers with rod-like structures were synthesized using a simple and green method; these nanostructures were evaluated by X-ray diffraction analysis, transmission electron microscopy, scanning electron microscopy, and X-ray energy diffraction spectroscopy. Additionally, the prepared nanowhiskers could significantly reduce the survival of Leishmania major promastigotes, at a concentration of 500 μg/mL; the survival of promastigotes was reduced to ≃ 26%. According to the results obtained from MTT test (in vitro), it can be proposed that further studies should be conducted to evaluate anti-leishmaniasis activity of these types of nanowhiskers in animal models. © 2021, The Author(s).