Exploring the Promising Potential of Induced Pluripotent Stem Cells in Cancer Research and Therapy

Exploring the Promising Potential of Induced Pluripotent Stem Cells in Cancer Research and Therapy Publisher Pubmed

Chehelgerdi M^{1, 2} ; Behdarvand Dehkordi F^{1, 2} ; Chehelgerdi M^{1, 2} ; Kabiri H^{1, 2} ; Salehiandehkordi H³ ; Abdolvand M⁴ ; Salmanizadeh S⁵ ; Rashidi M^{6, 7} ; Niazmand A⁴ ; Ahmadi S⁸ ; Feizbakhshan S⁴ ; Kabiri S^{1, 2} ; Vatandoost N⁹ ; Ranjbarnejad T⁴

Show Affiliations

1. Novin Genome (NG) Lab, Research and Development Center for Biotechnology, Shahrekord, Iran
2. Young Researchers and Elite Club, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran
3. College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China
4. Department of Genetics and Molecular Biology, School of Medicine, Isfahan University of Medical Science, Isfahan, Iran
5. Department of Cell and Molecular Biology and Microbiology, Faculty of Biological Science and Technology, University of Isfahan, Hezar-Jereeb Street, Isfahan, 81746-73441, Iran
6. Department Pharmacology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
7. The Health of Plant and Livestock Products Research Center, Mazandaran University of Medical Sciences, Sari, Iran
8. Department of Molecular and Medical Genetics, Tbilisi State Medical University, Tbilisi, Georgia
9. Pediatric Inherited Diseases Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Molecular Cancer Published:2023

Abstract

The advent of iPSCs has brought about a significant transformation in stem cell research, opening up promising avenues for advancing cancer treatment. The formation of cancer is a multifaceted process influenced by genetic, epigenetic, and environmental factors. iPSCs offer a distinctive platform for investigating the origin of cancer, paving the way for novel approaches to cancer treatment, drug testing, and tailored medical interventions. This review article will provide an overview of the science behind iPSCs, the current limitations and challenges in iPSC-based cancer therapy, the ethical and social implications, and the comparative analysis with other stem cell types for cancer treatment. The article will also discuss the applications of iPSCs in tumorigenesis, the future of iPSCs in tumorigenesis research, and highlight successful case studies utilizing iPSCs in tumorigenesis research. The conclusion will summarize the advancements made in iPSC-based tumorigenesis research and the importance of continued investment in iPSC research to unlock the full potential of these cells. © 2023, The Author(s).

Related Docs

View other Related Docs

1. Differentiation of Human Induced Pluripotent Stem Cells Into Erythroid Cells, Stem Cell Research and Therapy (2020)

2. Engaging Stemness Improves Cancer Immunotherapy, Cancer Letters (2023)

3. Induced Pluripotent Stem Cell As a New Source for Cancer Immunotherapy, Genetics Research International (2016)

4. Recent Advances in Therapeutic Applications of Induced Pluripotent Stem Cells, Cellular Reprogramming (2017)

5. Three-Dimensional in Vitro Models: A Promising Tool to Scale-Up Breast Cancer Research, ACS Biomaterials Science and Engineering (2022)

6. Administration of Stem Cells Against Cardiovascular Diseases With a Focus on Molecular Mechanisms: Current Knowledge and Prospects, Tissue and Cell (2023)

7. Organoid Technology: Current Standing and Future Perspectives, Stem Cells (2021)

8. Regulation of Dna Methylation Machinery by Epi-Mirnas in Human Cancer: Emerging New Targets in Cancer Therapy, Cancer Gene Therapy (2021)

Experts (# of related papers)

View all Related Experts

Shaghayegh Haghjooy Javanmard (3)

Laleh Shariati (2)

Style	Citing Format
MLA	Chehelgerdi M, et al.. "Exploring the Promising Potential of Induced Pluripotent Stem Cells in Cancer Research and Therapy." Molecular Cancer, vol. 22, no. 1, 2023, pp. -.
APA	Chehelgerdi M, Behdarvand Dehkordi F, Chehelgerdi M, Kabiri H, Salehiandehkordi H, Abdolvand M, Salmanizadeh S, Rashidi M, Niazmand A, Ahmadi S, Feizbakhshan S, Kabiri S, Vatandoost N, Ranjbarnejad T (2023). Exploring the Promising Potential of Induced Pluripotent Stem Cells in Cancer Research and Therapy. Molecular Cancer, 22(1), -.
Chicago	Chehelgerdi M, Behdarvand Dehkordi F, Chehelgerdi M, Kabiri H, Salehiandehkordi H, Abdolvand M, Salmanizadeh S, et al.. "Exploring the Promising Potential of Induced Pluripotent Stem Cells in Cancer Research and Therapy." Molecular Cancer 22, no. 1 (2023): -.
Harvard	Chehelgerdi M et al. (2023) 'Exploring the Promising Potential of Induced Pluripotent Stem Cells in Cancer Research and Therapy', Molecular Cancer, 22(1), pp. -.
Vancouver	Chehelgerdi M, Behdarvand Dehkordi F, Chehelgerdi M, Kabiri H, Salehiandehkordi H, Abdolvand M, et al.. Exploring the Promising Potential of Induced Pluripotent Stem Cells in Cancer Research and Therapy. Molecular Cancer. 2023;22(1):-.
BibTex	@article{ author = {Chehelgerdi M and Behdarvand Dehkordi F and Chehelgerdi M and Kabiri H and Salehiandehkordi H and Abdolvand M and Salmanizadeh S and Rashidi M and Niazmand A and Ahmadi S and Feizbakhshan S and Kabiri S and Vatandoost N and Ranjbarnejad T}, title = {Exploring the Promising Potential of Induced Pluripotent Stem Cells in Cancer Research and Therapy}, journal = {Molecular Cancer}, volume = {22}, number = {1}, pages = {-}, year = {2023} }
RIS	TY - JOUR AU - Chehelgerdi M AU - Behdarvand Dehkordi F AU - Chehelgerdi M AU - Kabiri H AU - Salehiandehkordi H AU - Abdolvand M AU - Salmanizadeh S AU - Rashidi M AU - Niazmand A AU - Ahmadi S AU - Feizbakhshan S AU - Kabiri S AU - Vatandoost N AU - Ranjbarnejad T TI - Exploring the Promising Potential of Induced Pluripotent Stem Cells in Cancer Research and Therapy JO - Molecular Cancer VL - 22 IS - 1 SP - EP - PY - 2023 ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract