Efficient Synthesis of Polyfunctionalized Pyrimidine Derivatives

Efficient Synthesis of Polyfunctionalized Pyrimidine Derivatives Publisher

Mahdavi M¹ ; Kianfard H² ; Saeedi M^{3, 4} ; Ranjbar PR² ; Shafiee A⁵

Show Affiliations

1. Drug Design and Development Research Center, Tehran University of Medical Sciences Theran, Iran
2. School of Chemistry, College of Science, University of Tehran, PO Box 14155-6455, Tehran, Iran
3. Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
4. Persian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, Tehran, Iran
5. Department of Medicinal Chemistry, Faculty of Pharmacy, Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Synlett Published:2016

Abstract

A simple and direct procedure was developed for the synthesis of a novel series of polyfunctionalized pyrimidines. They were prepared via reaction of N-(substituted carbamothioyl)benzimidamides (prepared from the reaction of benzimidamide hydrochloride and isothiocyanates) and malononitrile in the presence of CuBr/Et3N in DMF at 80 °C. © Georg Thieme Verlag Stuttgart, New York.

Style	Citing Format
MLA	Mahdavi M, et al.. "Efficient Synthesis of Polyfunctionalized Pyrimidine Derivatives." Synlett, vol. 27, no. 11, 2016, pp. 1689-1692.
APA	Mahdavi M, Kianfard H, Saeedi M, Ranjbar PR, Shafiee A (2016). Efficient Synthesis of Polyfunctionalized Pyrimidine Derivatives. Synlett, 27(11), 1689-1692.
Chicago	Mahdavi M, Kianfard H, Saeedi M, Ranjbar PR, Shafiee A. "Efficient Synthesis of Polyfunctionalized Pyrimidine Derivatives." Synlett 27, no. 11 (2016): 1689-1692.
Harvard	Mahdavi M et al. (2016) 'Efficient Synthesis of Polyfunctionalized Pyrimidine Derivatives', Synlett, 27(11), pp. 1689-1692.
Vancouver	Mahdavi M, Kianfard H, Saeedi M, Ranjbar PR, Shafiee A. Efficient Synthesis of Polyfunctionalized Pyrimidine Derivatives. Synlett. 2016;27(11):1689-1692.
BibTex	@article{ author = {Mahdavi M and Kianfard H and Saeedi M and Ranjbar PR and Shafiee A}, title = {Efficient Synthesis of Polyfunctionalized Pyrimidine Derivatives}, journal = {Synlett}, volume = {27}, number = {11}, pages = {1689-1692}, year = {2016} }
RIS	TY - JOUR AU - Mahdavi M AU - Kianfard H AU - Saeedi M AU - Ranjbar PR AU - Shafiee A TI - Efficient Synthesis of Polyfunctionalized Pyrimidine Derivatives JO - Synlett VL - 27 IS - 11 SP - 1689 EP - 1692 PY - 2016 ER -

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Abstract