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Superparamagnetic Iron Oxide Nanoparticles for in Vivo Molecular and Cellular Imaging Publisher Pubmed



Sharifi S1 ; Seyednejad H2 ; Laurent S3, 4 ; Atyabi F5 ; Saei AA5, 6 ; Mahmoudi M5, 7, 8
Authors

Source: Contrast Media and Molecular Imaging Published:2015


Abstract

In the last decade, the biomedical applications of nanoparticles (NPs) (e.g. cell tracking, biosensing, magnetic resonance imaging (MRI), targeted drug delivery, and tissue engineering) have been increasingly developed. Among the various NP types, superparamagnetic iron oxide NPs (SPIONs) have attracted considerable attention for early detection of diseases due to their specific physicochemical properties and their molecular imaging capabilities. A comprehensive review is presented on the recent advances in the development of in vitro and in vivo SPION applications for molecular imaging, along with opportunities and challenges. © 2015 John Wiley & Sons, Ltd.
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