Tehran University of Medical Sciences

Science Communicator Platform

Share By
Precision Medicine in Brain Tumors: New Approaches Publisher



Akhlaghdoust M ; Bordbar S ; Nikoohemmat M ; Meftah E ; Rahimzadegan M ; Akbari S ; Zali A
Authors

Source: Interdisciplinary Cancer Research Published:2025


Abstract

Despite progress in identifying tumors, specialized treatments, and the introduction of new therapies, the forecast for those diagnosed with aggressive brain cancer is bleak, with a survival rate of under 20% after 2 years. This underscores the critical need for a more thorough understanding of the disease to develop more effective treatments. In this chapter, personalized cancer treatments, using precision medicine techniques, have shown potential in dealing with brain tumors resistant to conventional treatments. Clinical studies are underway to assess the lack of side effects and efficacy of new treatment methods for malignant brain tumors. While precision medicine is currently being used to treat CNS tumors, more extensive research is needed. This part gives a summary of the existing evidence on the role of precision medicine in treating primary CNS tumors, detailing the various tumor phenotypes, common genetic changes, and the effectiveness of precision medicine approaches. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2024.
Related Docs
View other Related Docs
1. The Epidemiology of Brain and Spinal Cord Tumors, Advances in Experimental Medicine and Biology (2023)
2. Crossing the Blood-Brain Barrier: Advancing Immunotherapy for Pediatric Brain Tumors, Interdisciplinary Cancer Research (2025)
3. A Viral Attack on Brain Tumors: The Potential of Oncolytic Virus Therapy, Journal of NeuroVirology (2024)
Experts (# of related papers)
View all Related Experts
Nima Rezaei (6)
Maryam Mohammadzadeh (1)
Other Related Docs
4. Radiomics: The New Promise for Differentiating Progression, Recurrence, Pseudoprogression, and Radionecrosis in Glioma and Glioblastoma Multiforme, Cancers (2023)
5. Interdisciplinary Approach in Neurological Cancers, Interdisciplinary Cancer Research (2025)
6. Genetic Prognostic Factors in Adult Diffuse Gliomas: A 10-Year Experience at a Single Institution, Cancers (2024)
7. Geriatric Grade 2 and 3 Gliomas: A National Cancer Database Analysis of Demographics, Treatment Utilization, and Survival, Journal of Clinical Neuroscience (2024)
8. Tumor Immunology, Clinical Immunology (2022)
9. Spatial Profiling Technologies and Applications for Brain Cancers, Expert Review of Molecular Diagnostics (2021)
10. Predictive Molecular Biomarkers of Radiosensitivity in Adult Glioma: A Narrative Review, BMC Cancer (2025)
11. Potential Role of Artificial Intelligence in the Treatment of Glioblastoma in Children and Adults, Interdisciplinary Cancer Research (2025)
12. Radiomics Can Distinguish Pediatric Supratentorial Embryonal Tumors, High-Grade Gliomas, and Ependymomas, American Journal of Neuroradiology (2022)
13. Descriptive Epidemiology of Brain and Central Nervous System Tumours: Results From Iran National Cancer Registry, 2010-2014, Journal of Cancer Epidemiology (2020)
14. Pre-Operative Mri-Based Radiomics for Predicting Telomerase Reverse Transcriptase Promoter Mutation Status in Glioma Patients: A Systematic Review and Meta-Analysis, Neurosurgical Review (2026)
15. Recent Advances in Glioma Cancer Treatment: Conventional and Epigenetic Realms, Vaccines (2022)
16. The Role of Aquaporin 4 in Brain Tumors: Implications for Pathophysiology, Diagnosis and Therapy, Molecular Biology Reports (2022)
17. Diagnostic Accuracy of Deep Learning Models in Predicting Glioma Molecular Markers: A Systematic Review and Meta-Analysis, Diagnostics (2025)
18. Immune Checkpoint Inhibitor (Ici) Therapy in Central Nervous System Cancers: State-Of-The-Art and Future Outlook, International Immunopharmacology (2025)
19. Hotair Expression As a Biomarker in Glioblastoma Multiforme: A Comprehensive Meta-Analysis of Current Evidence, Biomarkers in Medicine (2025)
20. Radiomics and Artificial Intelligence in Radiotheranostics: A Review of Applications for Radioligands Targeting Somatostatin Receptors and Prostate-Specific Membrane Antigens, Diagnostics (2024)