Roles of Mesenchymal Stem Cells in Breast Cancer Therapy: Engineered Stem Cells and Exosomal Cell-Free Based Therapy

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Roles of Mesenchymal Stem Cells in Breast Cancer Therapy: Engineered Stem Cells and Exosomal Cell-Free Based Therapy Publisher Pubmed

Mk Fath Mohsen KARAMI ; Ss Zadian Seyed SAJJAD ; Smb Torbati Samaneh Mohammad BAGHERZADEH ; V Saqagandomabadi VAHID ; Oy Afshar Omid YOUSEFI ; Ma Khalilzad Mohammad AMIN ; S Abedi SARA ; A Moliani AFSHIN ; G Barati GHASEM

Source: Current Molecular Medicine Published:2025

Abstract

Breast cancer has a high prevalence among women, with a high mortality rate. The number of people who suffer from breast cancer disease is increasing, whereas metastatic cancers are mostly incurable, and existing therapies have unfavorable side effects. For an extended duration, scientists have dedicated their efforts to exploring the potential of mesenchymal stem cells (MSCs) for the treatment of metastatic cancers, including breast cancer. MSCs could be genetically engineered to boost their anticancer potency. Furthermore, MSCs can transport oncolytic viruses, suicide genes, and anticancer medicines to tumors. Extracellular vesicles (EVs) are MSC products that have attracted scientist's attention as a cell-free treatment. This study narratively reviews the current state of knowledge on engineered MSCs and their EVs as promising treatments for breast cancer. © 2025 Elsevier B.V., All rights reserved.

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Style	Citing Format
MLA	Mk Fath Mohsen KARAMI, et al.. "Roles of Mesenchymal Stem Cells in Breast Cancer Therapy: Engineered Stem Cells and Exosomal Cell-Free Based Therapy." Current Molecular Medicine, vol. 25, no. 4, 2025, pp. 431-444.
APA	Mk Fath Mohsen KARAMI, Ss Zadian Seyed SAJJAD, Smb Torbati Samaneh Mohammad BAGHERZADEH, V Saqagandomabadi VAHID, Oy Afshar Omid YOUSEFI, Ma Khalilzad Mohammad AMIN, S Abedi SARA, A Moliani AFSHIN, G Barati GHASEM (2025). Roles of Mesenchymal Stem Cells in Breast Cancer Therapy: Engineered Stem Cells and Exosomal Cell-Free Based Therapy. Current Molecular Medicine, 25(4), 431-444.
Chicago	Mk Fath Mohsen KARAMI, Ss Zadian Seyed SAJJAD, Smb Torbati Samaneh Mohammad BAGHERZADEH, V Saqagandomabadi VAHID, Oy Afshar Omid YOUSEFI, Ma Khalilzad Mohammad AMIN, S Abedi SARA, A Moliani AFSHIN, G Barati GHASEM. "Roles of Mesenchymal Stem Cells in Breast Cancer Therapy: Engineered Stem Cells and Exosomal Cell-Free Based Therapy." Current Molecular Medicine 25, no. 4 (2025): 431-444.
Harvard	Mk Fath Mohsen KARAMI et al. (2025) 'Roles of Mesenchymal Stem Cells in Breast Cancer Therapy: Engineered Stem Cells and Exosomal Cell-Free Based Therapy', Current Molecular Medicine, 25(4), pp. 431-444.
Vancouver	Mk Fath Mohsen KARAMI, Ss Zadian Seyed SAJJAD, Smb Torbati Samaneh Mohammad BAGHERZADEH, V Saqagandomabadi VAHID, Oy Afshar Omid YOUSEFI, Ma Khalilzad Mohammad AMIN, et al.. Roles of Mesenchymal Stem Cells in Breast Cancer Therapy: Engineered Stem Cells and Exosomal Cell-Free Based Therapy. Current Molecular Medicine. 2025;25(4):431-444.
BibTex	@article{ author = {Mk Fath Mohsen KARAMI and Ss Zadian Seyed SAJJAD and Smb Torbati Samaneh Mohammad BAGHERZADEH and V Saqagandomabadi VAHID and Oy Afshar Omid YOUSEFI and Ma Khalilzad Mohammad AMIN and S Abedi SARA and A Moliani AFSHIN and G Barati GHASEM}, title = {Roles of Mesenchymal Stem Cells in Breast Cancer Therapy: Engineered Stem Cells and Exosomal Cell-Free Based Therapy}, journal = {Current Molecular Medicine}, volume = {25}, number = {4}, pages = {431-444}, year = {2025} }
RIS	TY - JOUR AU - Mk Fath Mohsen KARAMI AU - Ss Zadian Seyed SAJJAD AU - Smb Torbati Samaneh Mohammad BAGHERZADEH AU - V Saqagandomabadi VAHID AU - Oy Afshar Omid YOUSEFI AU - Ma Khalilzad Mohammad AMIN AU - S Abedi SARA AU - A Moliani AFSHIN AU - G Barati GHASEM TI - Roles of Mesenchymal Stem Cells in Breast Cancer Therapy: Engineered Stem Cells and Exosomal Cell-Free Based Therapy JO - Current Molecular Medicine VL - 25 IS - 4 SP - 431 EP - 444 PY - 2025 ER -

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