Tehran University of Medical Sciences

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Faculty Members have conducted research related to the Angiotensin-Converting Enzyme 2 (Ace2) Receptor and Sars-Cov-2: Potential Therapeutic Targeting
Farshid Noorbakhsh
Farshid Noorbakhsh

Professor of Medical Immunology

Department Immunology

School of Medicine

Tehran University of Medical Sciences

Related Documents
1. Sars-Cov-2 and Covid-19, Basic and Clinical Aspects of the Human Pandemic: A Review, Iranian Journal of Public Health (2021)
2. Immunology, Immunopathogenesis and Immunotherapeutics of Covid-19; an Overview, International Immunopharmacology (2021)
All Documents
1. Analyzing the Role of Circsnx5 in an Animal Model of Multiple Sclerosis, Iranian Journal of Allergy, Asthma and Immunology (2025)
2. Dual Checkpoint Inhibition in M2 Macrophages Via Anti-Pd-L1 and Sirna-Loaded M1-Exosomes: Enhancing Tumor Immunity Through Rna-Targeting Strategies, European Journal of Pharmacology (2025)
3. Elucidating the Significance of Zonulin in the Pathogenesis of Chronic Inflammatory Disorders: Emphasis on Intestinal Barrier Function and Tight Junction Regulation, Current Medicinal Chemistry (2025)
4. Enhancing the Anti-Tumor Activity and Reprogramming M2 Macrophages by Delivering Sirnas Against Sirpα and Stat6 Via M1 Exosomes and Combining With Anti-Pd-L1, Life Sciences (2025)
5. Blockade of Proteinase-Activated Receptor 2 (Par2) Attenuates Neuroinflammation in Experimental Autoimmune Encephalomyelitis, Journal of Pharmacology and Experimental Therapeutics (2024)
6. Circznf609 and Circnfix As Possible Regulators of Glioblastoma Pathogenesis Via Mir-145-5P/Egfr Axis, Scientific Reports (2024)
7. Involvement of Nron and Tug1 Long Noncoding Rnas in Inflammation and the Pathogenesis of Eae, Nucleosides# Nucleotides and Nucleic Acids (2024)
8. A Combination of Physical and Chemical Treatments Is More Effective in the Preparation of Acellular Uterine Scaffolds, Cell Journal (2023)
9. Isolation and in Vitro Expansion of Regulatory T Cells From Β-Thalassemia Major Kids and in Vitro Evaluation of Their Plasticity and Inhibitory Effects in the Presence of Pro-Inflammatory Cytokines, International Archives of Allergy and Immunology (2023)
10. Microrna-124 Enhances T Cells Functions by Manipulating the Lactic Acid Metabolism of Tumor Cells, Iranian Journal of Allergy# Asthma and Immunology (2023)
11. Neuroinflammatory Response in Reward-Associated Psychostimulants and Opioids: A Review, Cellular and Molecular Neurobiology (2023)
12. Rewiring of Mirna-Mrna Bipartite Co-Expression Network As a Novel Way to Understand the Prostate Cancer Related Players, Systems Biology in Reproductive Medicine (2023)
13. Sars-Cov-2 Helicase Might Interfere With Cellular Nonsense-Mediated Rna Decay: Insights From a Bioinformatics Study, BMC Genomic Data (2023)
14. Vitamins a and D Enhance the Expression of Ror-Γ-Targeting Mirnas in a Mouse Model of Multiple Sclerosis, Molecular Neurobiology (2023)
15. A Review of Molecular Interplay Between Neurotrophins and Mirnas in Neuropsychological Disorders, Molecular Neurobiology (2022)
16. C1q/Tnf-Related Protein-1: Potential Biomarker for Early Diagnosis of Autism Spectrum Disorder, International Journal of Immunopathology and Pharmacology (2022)
17. Development of a Multiepitope Vaccine Against Sars-Cov-2: Immunoinformatics Study, JMIR Bioinformatics and Biotechnology (2022)
18. Influence of Vitamins a and D on the Expression of Microrna27-3P Isoforms and Gata3 in Experimental Autoimmune Encephalomyelitis, Iranian Journal of Allergy# Asthma and Immunology (2022)
19. Long Non-Coding Rna Hotair Induces the Pi3k/Akt/Mtor Signaling Pathway in Breast Cancer Cells, Revista da Associacao Medica Brasileira (2022)
20. Rbioapi: User-Friendly R Interface to Biologic Web Services' Api, Bioinformatics (2022)
21. The Importance of Regulatory Pathway Mediated by Circ0001955 in Colorectal Cancer, Experimental and Molecular Pathology (2022)
22. Attenuation of Ventilator-Induced Lung Injury Through Suppressing the Pro-Inflammatory Signaling Pathways: A Review on Preclinical Studies, Molecular Immunology (2021)
23. Cell Therapy in Transplantation: A Comprehensive Review of the Current Applications of Cell Therapy in Transplant Patients With the Focus on Tregs, Car Tregs, and Mesenchymal Stem Cells, International Immunopharmacology (2021)
24. Combination Therapy of Phosphatidylserine Liposome With Cyclosporine a Improves Nephrotoxicity and Attenuates Delayed-Type Hypersensitivity Response, Life Sciences (2021)
25. Elevated Fecal and Serum Calprotectin in Covid-19 Are Not Consistent With Gastrointestinal Symptoms, Scientific Reports (2021)
26. Immunology, Immunopathogenesis and Immunotherapeutics of Covid-19; an Overview, International Immunopharmacology (2021)
27. Importance of Circ0009910 in Colorectal Cancer Pathogenesis As a Possible Regulator of Mir-145 and Peak1, World Journal of Surgical Oncology (2021)
28. Inflammation in an Animal Model of Multiple Sclerosis Leads to Microrna-25-3P Dysregulation Associated With Inhibition of Pten and Klf4, Iranian Journal of Allergy# Asthma and Immunology (2021)
29. Sars-Cov-2 and Covid-19, Basic and Clinical Aspects of the Human Pandemic: A Review, Iranian Journal of Public Health (2021)
30. Sars-Cov-2 Spike Protein Displays Sequence Similarities With Paramyxovirus Surface Proteins; a Bioinformatics Study, PLoS ONE (2021)
31. Targeted Knockdown of Tim3 by Short Hairpin Rnas Improves the Function of Anti-Mesothelin Car T Cells, Molecular Immunology (2021)
32. Construction and Functional Characterization of a Fully Human Anti-Mesothelin Chimeric Antigen Receptor (Car) Expressing T Cell, Iranian Journal of Allergy# Asthma and Immunology (2020)
33. Effect of Hypoxia Preconditioned Adipose-Derived Mesenchymal Stem Cell Conditioned Medium on Cerulein-Induced Acute Pancreatitis in Mice, Advanced Pharmaceutical Bulletin (2020)
34. Erratum: Changing the Tone of Clinical Study Design in the Cannabis Industry (Translational Neuroscience (2020) 13:11 (4-9) Doi: 10.1515/Tnsci-2020-0002), Translational Neuroscience (2020)
35. Expression Level of Long Noncoding Rna Nkila-Mir103-Mir107 Inflammatory Axis and Its Clinical Significance As Potential Biomarker in Patients With Colorectal Cancer, Journal of Research in Medical Sciences (2020)
36. Genetic and Pharmacological Targeting of A2a Receptor Improves Function of Anti-Mesothelin Car T Cells, Journal of Experimental and Clinical Cancer Research (2020)
37. Higher Prevalence of Asymptomatic or Mild Covid-19 in Children, Claims and Clues, Journal of Medical Virology (2020)
38. Inhibiting Mir-27A and Mir-142-5P Attenuate Nonalcoholic Fatty Liver Disease by Regulating Nrf2 Signaling Pathway, IUBMB Life (2020)
39. Metformin Loaded Phosphatidylserine Nanoliposomes Improve Memory Deficit and Reduce Neuroinflammation in Streptozotocin-Induced Alzheimer's Disease Model, Life Sciences (2020)
40. Optimising Effective Parameters to Improve Performance Quality in Lateral Flow Immunoassay for Detection of Pbp2a in Methicillin-Resistant Staphylococcus Aureus (Mrsa), Journal of Experimental Nanoscience (2020)
41. Pharmacological Targeting of Immune Checkpoint A2ar Improves Function of Anti-Cd19 Car T Cells in Vitro, Immunology Letters (2020)
42. Staphylococcal Enterotoxin B Increased Severity of Experimental Model of Multiple Sclerosis, Microbial Pathogenesis (2020)
43. The Upregulation of Hsa-Mir-181B-1 and Downregulation of Its Target Cyld in the Late-Stage of Tumor Progression of Breast Cancer, Indian Journal of Clinical Biochemistry (2020)
44. The Upregulation of Hsa-Mir-181B-1 and Downregulation of Its Target Cyld in the Late-Stage of Tumor Progression of Breast Cancer, Indian Journal of Clinical Biochemistry (2020)
45. Blood Lead Levels and Multiple Sclerosis: A Case-Control Study, Multiple Sclerosis and Related Disorders (2019)
46. Construction and Functional Characterization of a Fully Human Anti-Cd19 Chimeric Antigen Receptor (Hucar)-Expressing Primary Human T Cells, Journal of Cellular Physiology (2019)
47. Expression of Mir-15B-5P, Mir-21-5P, and Smad7 in Lung Tissue of Sulfur Mustard-Exposed Individuals With Long-Term Pulmonary Complications, Iranian Journal of Allergy# Asthma and Immunology (2019)
48. Malat1 Long Noncoding Rna Regulates Inflammation and Leukocyte Differentiation in Experimental Autoimmune Encephalomyelitis, Journal of Neuroimmunology (2019)
49. Microrna-21 and Microrna-29A Modulate the Expression of Collagen in Dermal Fibroblasts of Patients With Systemic Sclerosis, Autoimmunity (2019)
50. Microrna-92A Drives Th1 Responses in the Experimental Autoimmune Encephalomyelitis, Inflammation (2019)
51. Microrna-92A Drives Th1 Responses in the Experimental Autoimmune Encephalomyelitis, Inflammation (2019)
52. Switching From High-Fat Diet to Foods Containing Resveratrol As a Calorie Restriction Mimetic Changes the Architecture of Arcuate Nucleus to Produce More Newborn Anorexigenic Neurons, European Journal of Nutrition (2019)
53. Therapeutic Potential of Conditioned Medium Derived From Oligodendrocytes Cultured in a Self-Assembling Peptide Nanoscaffold in Experimental Autoimmune Encephalomyelitis, Brain Research (2019)
54. Zika Virus Infection, Basic and Clinical Aspects: A Review Article, Iranian Journal of Public Health (2019)
55. Circulating Helper T-Cell Subsets and Regulatory T Cells in Patients With Common Variable Immunodeficiency Without Known Monogenic Disease, Journal of Investigational Allergology and Clinical Immunology (2018)
56. Collagen Ii-Primed Foxp3 Transduced T Cells Ameliorate Collagen-Induced Arthritis in Rats: The Effect of Antigenic Priming on T Regulatory Cell Function, Iranian Journal of Allergy# Asthma and Immunology (2018)
57. Evaluation of Regulatory T Lymphocytes and Il2ra and Foxp3 Gene Expression in Peripheral Mononuclear Cells From Patients With Amyotrophic Lateral Sclerosis, Irish Journal of Medical Science (2018)
58. Evidence for the Link Between Defective Autophagy and Inflammation in Peripheral Blood Mononuclear Cells of Type 2 Diabetic Patients, Journal of Physiology and Biochemistry (2018)
59. Immunomodulatory Function of Treg-Derived Exosomes Is Impaired in Patients With Relapsing-Remitting Multiple Sclerosis, Immunologic Research (2018)
60. In Vitro Study of Hax1 Gene Therapy by Retro Viral Transduction As a Therapeutic Target in Severe Congenital Neutropenia, European Cytokine Network (2018)
61. Microenvironment Proteinases, Proteinase-Activated Receptor Regulation, Cancer and Inflammation, Biological Chemistry (2018)
62. Microrna-150 Targets Pu.1 and Regulates Macrophage Differentiation and Function in Experimental Autoimmune Encephalomyelitis, Journal of Neuroimmunology (2018)
63. Prophylactic Dna Vaccine Targeting Foxp3+ Regulatory T Cells Depletes Myeloid-Derived Suppressor Cells and Improves Anti-Melanoma Immune Responses in a Murine Model, Cancer Immunology, Immunotherapy (2018)
64. Prophylactic Dna Vaccine Targeting Foxp3+ Regulatory T Cells Depletes Myeloid-Derived Suppressor Cells and Improves Anti-Melanoma Immune Responses in a Murine Model, Cancer Immunology# Immunotherapy (2018)
65. Resveratrol Promotes the Arcuate Nucleus Architecture Remodeling to Produce More Anorexigenic Neurons in High-Fat-Diet–Fed Mice, Nutrition (2018)
66. Scrutinizing the Expression and Blockade of Inhibitory Molecules Expressed on T Cells From Acute Myeloid Leukemia Patients, Iranian Journal of Allergy# Asthma and Immunology (2018)
67. The Cardiac Niche Role in Cardiomyocyte Differentiation of Rat Bone Marrow-Derived Stromal Cells: Comparison Between Static and Microfluidic Cell Culture Methods, EXCLI Journal (2018)
68. The Imbalance of Circulating T Helper Subsets and Regulatory T Cells in Patients With Lrba Deficiency: Correlation With Disease Severity, Journal of Cellular Physiology (2018)
69. Toll-Like Receptors Pathway in Common Variable Immune Deficiency (Cvid) and X-Linked Agammaglobulinemia (Xla), European Cytokine Network (2018)
70. A Simplified Protocol for the Purification of Schwann Cells and Exosome Isolation From C57bl/6 Mice, Reports of Biochemistry and Molecular Biology (2017)
71. Altered Expression of Igf-I System in Neurons of the Inflamed Spinal Cord During Acute Experimental Autoimmune Encephalomyelitis, Journal of Comparative Neurology (2017)
72. Cd73 Specific Sirna Loaded Chitosan Lactate Nanoparticles Potentiate the Antitumor Effect of a Dendritic Cell Vaccine in 4T1 Breast Cancer Bearing Mice, Journal of Controlled Release (2017)
73. Improvement of Memory and Learning by Intracerebroventricular Microinjection of T3 in Rat Model of Ischemic Brain Stroke Mediated by Upregulation of Bdnf and Gdnf in Ca1 Hippocampal Region, DARU# Journal of Pharmaceutical Sciences (2017)
74. Increased Expression of Toll-Like Receptors 2 and 4 in Renal Transplant Recipients That Develop Allograft Dysfunction: A Cohort Study, Iranian Journal of Immunology (2017)
75. Microrna-142 Regulates Inflammation and T Cell Differentiation in an Animal Model of Multiple Sclerosis, Journal of Neuroinflammation (2017)
76. Microrna-181 Variants Regulate T Cell Phenotype in the Context of Autoimmune Neuroinflammation, Frontiers in Immunology (2017)
77. Mir-181 Interacts With Signaling Adaptor Molecule Denn/Madd and Enhances Tnf-Induced Cell Death, PLoS ONE (2017)
78. Spectrum of Pediatric Tumors Diagnosed by Fine-Needle Aspiration Cytology, Medicine (United States) (2017)
79. Suppressed Oligodendrocyte Steroidogenesis in Multiple Sclerosis: Implications for Regulation of Neuroinflammation, GLIA (2017)
80. Identification of Proteins Derived From Listeria Monocytogenes Inducing Human Dendritic Cell Maturation, Tumor Biology (2016)
81. Increased Levels of Cd4+ and Cd8+ T Cells Expressing Ccr1 in Patients Developing Allograft Dysfunction; a Cohort Study, Transplant Immunology (2016)
82. Inhibition of Hif-1Α Enhances Anti-Tumor Effects of Dendritic Cell-Based Vaccination in a Mouse Model of Breast Cancer, Cancer Immunology# Immunotherapy (2016)
83. Inhibition of Microrna-21 Induces Apoptosis in Dermal Fibroblasts of Patients With Systemic Sclerosis, International Journal of Dermatology (2016)
84. Repeated Administration of Mercury Intensifies Brain Damage in Multiple Sclerosis Through Mitochondrial Dysfunction, Iranian Journal of Pharmaceutical Research (2016)
85. Reproducible and Reliable Real-Time Pcr Assay to Measure Mature Form of Mir-141, Applied Immunohistochemistry and Molecular Morphology (2016)
86. Systems Biomedicine of Rabies Delineates the Affected Signaling Pathways, Frontiers in Microbiology (2016)
87. The Effect of Melatonin on Behavioral, Molecular, and Histopathological Changes in Cuprizone Model of Demyelination, Molecular Neurobiology (2016)
88. The Involvement of Protein Kinase G Inhibitor in Regulation of Apoptosis and Autophagy Markers in Spatial Memory Deficit Induced by Aβ, Fundamental and Clinical Pharmacology (2016)
89. Ameliorating of Memory Impairment and Apoptosis in Amyloid Β-Injected Rats Via Inhibition of Nitric Oxide Synthase: Possible Participation of Autophagy, Iranian Journal of Pharmaceutical Research (2015)
90. Application of “Omics” Technologies for Diagnosis and Pathogenesis of Neurological Infections, Current Neurology and Neuroscience Reports (2015)
91. Interaction Between the Protective Effects of Cannabidiol and Palmitoylethanolamide in Experimental Model of Multiple Sclerosis in C57bl/6 Mice, Neuroscience (2015)
92. Investigating the Effect of Rs3783605 Single-Nucleotide Polymorphism on the Activity of Vcam-1 Promoter in Human Umbilical Vein Endohelial Cells, Iranian Journal of Allergy# Asthma and Immunology (2015)
93. Mapk and Jak/Stat Pathways Targeted by Mir-23A and Mir-23B in Prostate Cancer: Computational and in Vitro Approaches, Tumor Biology (2015)
94. Microrna-29A Induces Apoptosis Via Increasing the Bax:Bcl-2 Ratio in Dermal Fibroblasts of Patients With Systemic Sclerosis, Autoimmunity (2015)
95. Protective Effect of a Camp Analogue on Behavioral Deficits and Neuropathological Changes in Cuprizone Model of Demyelination, Molecular Neurobiology (2015)