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Prevalence, Deaths, and Disability-Adjusted Life-Years Due to Asthma and Its Attributable Risk Factors in 204 Countries and Territories, 1990-2019 Publisher Pubmed



Safiri S1, 2 ; Carsonchahhoud K8, 9 ; Karamzad N3 ; Sullman MJM10, 11 ; Nejadghaderi SA2, 5 ; Taghizadieh A1 ; Bell AW12, 13 ; Kolahi AA6 ; Ansarin K4 ; Mansournia MA7 ; Collins GS14, 15 ; Kaufman JS16
Authors
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Authors Affiliations
  1. 1. Tuberculosis and Lung Disease Research Center, Department of Community Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tehran, Tabriz, Iran
  2. 2. Research Center for Integrative Medicine in Aging, Aging Research Institute, Tabriz University of Medical Sciences, Tehran, Tabriz, Iran
  3. 3. Nutrition Research Center, Department of Biochemistry and Diet Therapy, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tehran, Tabriz, Iran
  4. 4. Rahat Breath and Sleep Research Center, Tabriz University of Medical Sciences, Tehran, Tabriz, Iran
  5. 5. Systematic Review and Meta-analysis Expert Group (SRMEG), Universal Scientific Education and Research Network (USERN), Tehran, Iran
  6. 6. Social Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  7. 7. Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  8. 8. Australian Centre for Precision Health, University of South Australia, Adelaide, SA, Australia
  9. 9. School of Medicine, University of Adelaide, Adelaide, SA, Australia
  10. 10. Department of Life and Health Sciences, University of Nicosia, Nicosia, Cyprus
  11. 11. Department of Social Sciences, University of Nicosia, Nicosia, Cyprus
  12. 12. Health Sciences Integrated Program, Northwestern University, Chicago, IL, United States
  13. 13. Department of Global Health and Social Medicine, Harvard University, Boston, MA, United States
  14. 14. Centre for Statistics in Medicine, NDORMS, Botnar Research Centre, University of Oxford, England, Oxford, United Kingdom
  15. 15. NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, England, Oxford, United Kingdom
  16. 16. Department of Epidemiology, Biostatistics and Occupational Health, Faculty of Medicine, McGill University, Montreal, QC, Canada

Source: Chest Published:2022


Abstract

Background: Understanding global trends in the point prevalence, deaths, and disability-adjusted life-years (DALYs) for asthma will facilitate evidence-based decision-making. Research Question: What are the global, regional, and national burdens of asthma in 204 countries and territories between 1990 and 2019 by age, sex, and sociodemographic index (SDI)? Study Design and Methods: Publicly available data from the Global Burden of Disease study from 1990 through 2019 were used. All estimates were presented as counts and age-standardized rates per 100,000, along with their associated uncertainty intervals. Results: In 2019, the global age-standardized point prevalence and death rates for asthma were 3,415.5 and 5.8 per 100,000, which represent a 24% and 51.3% decrease since 1990, respectively. Moreover, in 2019, the global age-standardized DALY rate was 273.6 and the global point prevalence of asthma was highest in the group 5 to 9 years of age. Also in 2019, the United States (10,399.3) showed the highest age-standardized point prevalence rate of asthma. Generally, the burden of asthma decreased with increasing SDI. Globally, high BMI (16.9%), smoking (9.9%), and occupational asthmagens (8.8%) contributed to the 2019 asthma DALYs. Interpretation: Asthma remains an important public health issue, particularly in regions with low socioeconomic development. Future research is needed to examine thoroughly the associations asthma has with its risk factors and the factors impeding optimal self-management. Further research also is needed to understand and implement better the interventions that have reduced the burden of asthma. © 2021 American College of Chest Physicians
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