Preferential Solvation of 4-(4-Ethoxyphenyl)-5-(3,4,5-Trimethoxybenzoyl)-3,4-Dihydropyrimidin-2(1H)-One in {Peg 400 (1) + Water (2)} Mixtures

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Preferential Solvation of 4-(4-Ethoxyphenyl)-5-(3,4,5-Trimethoxybenzoyl)-3,4-Dihydropyrimidin-2(1H)-One in {Peg 400 (1) + Water (2)} Mixtures Publisher

Jouyban A^{1, 2} ; Shakeel F³ ; Bhat MA⁴ ; Martinez F⁶

Show Affiliations

1. Pharmaceutical Analysis Research Center, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
2. Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran
3. Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia
4. Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia
5. Department of Chemistry, University of North Texas, Denton, TX, United States
6. Grupo De Investigaciones Farmaceutico-Fisicoquimicas, Departamento De Farmacia, Universidad Nacional De Colombia, Bogota, D. C, Colombia

Source: Physics and Chemistry of Liquids Published:2021

Abstract

The reported equilibrium mole fraction solubility of 4-(4-ethoxyphenyl)-5-(3,4,5-trimethoxybenzoyl)-3,4-dihydropyrimidin-2(1H)-one (DHP-5) in some {polyethylene glycol (PEG 400 (1) + water (2)} mixtures at 298.2 K has been used to evaluate the preferential solvation of this compound by the mixture components. First, molar volume and Hildebrand solubility parameter of DHP-5 were calculated as 277.7 cm3 mol–1 and 25.11 MPa1/2, respectively, by means of Fedors’ method. In this way, by using the inverse Kirkwood–Buff integrals method, it is observed that this compound is preferentially solvated by PEG molecules in all the mixtures. Thus, maximum preferential solvation parameter by PEG was observed in the mixture x 1 = 0.15 being 1.55 × 10–2. © 2020 Informa UK Limited, trading as Taylor & Francis Group.

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Style	Citing Format
MLA	Jouyban A, et al.. "Preferential Solvation of 4-(4-Ethoxyphenyl)-5-(3,4,5-Trimethoxybenzoyl)-3,4-Dihydropyrimidin-2(1H)-One in {Peg 400 (1) + Water (2)} Mixtures." Physics and Chemistry of Liquids, vol. 59, no. 3, 2021, pp. 423-430.
APA	Jouyban A, Shakeel F, Bhat MA, Martinez F (2021). Preferential Solvation of 4-(4-Ethoxyphenyl)-5-(3,4,5-Trimethoxybenzoyl)-3,4-Dihydropyrimidin-2(1H)-One in {Peg 400 (1) + Water (2)} Mixtures. Physics and Chemistry of Liquids, 59(3), 423-430.
Chicago	Jouyban A, Shakeel F, Bhat MA, Martinez F. "Preferential Solvation of 4-(4-Ethoxyphenyl)-5-(3,4,5-Trimethoxybenzoyl)-3,4-Dihydropyrimidin-2(1H)-One in {Peg 400 (1) + Water (2)} Mixtures." Physics and Chemistry of Liquids 59, no. 3 (2021): 423-430.
Harvard	Jouyban A et al. (2021) 'Preferential Solvation of 4-(4-Ethoxyphenyl)-5-(3,4,5-Trimethoxybenzoyl)-3,4-Dihydropyrimidin-2(1H)-One in {Peg 400 (1) + Water (2)} Mixtures', Physics and Chemistry of Liquids, 59(3), pp. 423-430.
Vancouver	Jouyban A, Shakeel F, Bhat MA, Martinez F. Preferential Solvation of 4-(4-Ethoxyphenyl)-5-(3,4,5-Trimethoxybenzoyl)-3,4-Dihydropyrimidin-2(1H)-One in {Peg 400 (1) + Water (2)} Mixtures. Physics and Chemistry of Liquids. 2021;59(3):423-430.
BibTex	@article{ author = {Jouyban A and Shakeel F and Bhat MA and Martinez F}, title = {Preferential Solvation of 4-(4-Ethoxyphenyl)-5-(3,4,5-Trimethoxybenzoyl)-3,4-Dihydropyrimidin-2(1H)-One in {Peg 400 (1) + Water (2)} Mixtures}, journal = {Physics and Chemistry of Liquids}, volume = {59}, number = {3}, pages = {423-430}, year = {2021} }
RIS	TY - JOUR AU - Jouyban A AU - Shakeel F AU - Bhat MA AU - Martinez F TI - Preferential Solvation of 4-(4-Ethoxyphenyl)-5-(3,4,5-Trimethoxybenzoyl)-3,4-Dihydropyrimidin-2(1H)-One in {Peg 400 (1) + Water (2)} Mixtures JO - Physics and Chemistry of Liquids VL - 59 IS - 3 SP - 423 EP - 430 PY - 2021 ER -

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