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Heart Targeted Nanoliposomal/Nanoparticles Drug Delivery: An Updated Review Publisher Pubmed



Cheraghi M1 ; Negahdari B2 ; Daraee H2, 3, 4 ; Eatemadi A2, 3, 4
Authors
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Authors Affiliations
  1. 1. Department of Cardiology, Lorestan University of Medical Sciences, Khoramabad, Iran
  2. 2. Department of Medical Biotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Medical Biotechnology, School of Medicine, Lorestan University of Medical sciences, Lorestan, Iran
  4. 4. Razi Herbal Medicine Research Center, Lorestan University of Medical Science, Iran

Source: Biomedicine and Pharmacotherapy Published:2017


Abstract

Nanoliposomes are type of nano-sized vesicles made of bi-layered phospholipid membranes with an aqueous interior. They have been demonstrated to deliver several materials like low molecular weight drugs, imaging agents, peptides, proteins, and nucleic acids. Nanoliposomes have been demonstrated to slowly release an encapsulated drug, thereby leading to sustained exposure to target region and improved efficacy. This ability of nano-liposomes can be harnessed to deliver therapeutic agents precisely to the infarcted heart. Accordingly, this article will review recent developments in the application of nano liposomes and nanoparticles as drug delivery systems to treat cardiovascular related disorders such as atherosclerosis, restenosis and myocardial infarction. © 2016 Elsevier Masson SAS
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