Potential Role of Regulatory B Cells in Immunological Diseases

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):

Share this content! On (X network) By

Potential Role of Regulatory B Cells in Immunological Diseases Publisher Pubmed

Valizadeh A¹ ; Sanaei R^{2, 3} ; Rezaei N^{1, 3} ; Azizi G⁴ ; Fekrvand S¹ ; Aghamohammadi A¹ ; Yazdani R¹

Show Affiliations

1. Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Science, Tehran, Iran
2. Immunology Research Center (IRC), Institute of Immunology and Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran
3. Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran
4. Non-Communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran

Source: Immunology Letters Published:2019

Abstract

Regulatory B cells (Bregs) are immune-modulating cells that affect the immune system by producing cytokines or cellular interactions. These cells have immunomodulatory effects on the immune system by cytokine production. The abnormalities in Bregs could be involved in various disorders such as autoimmunity, chronic infectious disease, malignancies, allergies, and primary immunodeficiencies are immune-related scenarios. Ongoing investigation could disclose the biology and the exact phenotype of these cells and also the assigned mechanisms of action of each subset, as a result, potential therapeutic strategies for treating immune-related anomalies. In this review, we collect the findings of human and mouse Bregs and the therapeutic efforts to change the pathogenicity of these cells in diverse disease. © 2019 European Federation of Immunological Societies

Related Docs

View other Related Docs

1. Autoimmune Diseases, Clinical Immunology (2022)

2. Role of B Cells in the Pathogenesis of Multiple Sclerosis: Mechanisms of Action, Multiple Sclerosis: A Mechanistic View (2016)

3. B Cells in Multiple Sclerosis Therapy—A Comprehensive Review, Acta Neurologica Scandinavica (2018)

4. Immune Regulatory Network in Successful Pregnancy and Reproductive Failures, Biomedicine and Pharmacotherapy (2017)

5. Role of Rare Immune Cells in Common Variable Immunodeficiency, Pediatric Allergy and Immunology (2022)

6. B Lymphocytes in Covid-19: A Tale of Harmony and Discordance, Archives of Virology (2023)

7. Monoclonal Antibodies in Multiple Sclerosis Treatment, Translational Neuroimmunology: Multiple Sclerosis: Volume 8 (2023)

8. Transitional Immature Regulatory B Cells and Regulatory Cytokines Can Discriminate Chronic Antibody-Mediated Rejection From Stable Graft Function, International Immunopharmacology (2020)

Experts (# of related papers)

View all Related Experts

Nima Rezaei (9)

Mohammad Ali Sahraian (5)

Other Related Docs

9. Evaluating the Efficacy and Safety of Zytuxtm (Rituximab, Aryogen Pharmed) in Iranian Multiple Sclerosis Patients: An Observational Study, Multiple Sclerosis and Related Disorders (2019)

10. Survivin and Autoimmunity; the Ins and Outs, Immunology Letters (2018)

11. The Possible Role of Interleukin-35 and Its Therapeutic Potential in Pemphigus, International Immunopharmacology (2017)

12. A Presentation of Ulcerative Colitis After Rituximab Therapy in a Patient With Multiple Sclerosis and Literature Review, Multiple Sclerosis and Related Disorders (2018)

13. Consensus Recommendations for the Diagnosis and Treatment of Multiple Sclerosis: 2019 Revisions to the Menactrims Guidelines, Multiple Sclerosis and Related Disorders (2020)

14. B Cell Modulation Strategies in the Improvement of Transplantation Outcomes, Molecular Immunology (2020)

15. Evaluation of Specific Antibody Responses in Patients With Selective Iga Deficiency and Ataxia Telangiectasia, Endocrine# Metabolic and Immune Disorders - Drug Targets (2022)

16. Multi-Omics Insights Into Autoimmune Thrombocytopenic Purpura, Comprehensive Hematology and Stem Cell Research: Volume 1-5 (2024)

17. Adaptive Immunity, Encyclopedia of Infection and Immunity (2022)

18. The Heterogeneous Pathogenesis of Selective Immunoglobulin a Deficiency, International Archives of Allergy and Immunology (2019)

19. Il-21 and Il-21 Receptor in the Immunopathogenesis of Multiple Sclerosis, Journal of Immunotoxicology (2016)

20. Consensus Recommendations for Diagnosis and Treatment of Multiple Sclerosis: 2023 Revision of the Menactrims Guidelines, Multiple Sclerosis and Related Disorders (2024)

21. Efficacy and Safety of Rituximab in Multiple Sclerosis: A Systematic Review and Meta-Analysis, Acta Neurologica Belgica (2023)

22. The Relationship Between Hla-G and Viral Loads in Non-Responder Hcv-Infected Patients After Combined Therapy With Ifn-Α2α and Ribavirin, Human Immunology (2015)

23. Quercetin As a Jak–Stat Inhibitor: A Potential Role in Solid Tumors and Neurodegenerative Diseases, Cellular and Molecular Biology Letters (2022)

24. Cancer Incidence in Iran in 2014: Results of the Iranian National Population-Based Cancer Registry, Cancer Epidemiology (2019)

25. Immune Microenvironment in Different Molecular Subtypes of Ductal Breast Carcinoma, Breast Cancer Research and Treatment (2021)

26. Candidiasis Associated With Very Early Onset Inflammatory Bowel Disease: First Il10rb Deficient Case From the National Iranian Registry and Review of the Literature, Clinical Immunology (2019)

27. The Homeostasis and Therapeutic Applications of Innate and Adaptive Immune Cells in Periodontitis, Oral Diseases (2023)

28. B Lymphocyte Subset Changes in Primary Membranous Nephropathy, Nephro-Urology Monthly (2019)

29. Targeting Bruton’S Tyrosine Kinase (Btk) As a Signaling Pathway in Immune-Mediated Diseases: From Molecular Mechanisms to Leading Treatments, Advances in Rheumatology (2024)

30. The Molecular Mechanisms of Vitamin a Deficiency in Multiple Sclerosis, Journal of Molecular Neuroscience (2016)

31. The Profile of Il-4, Il-5, Il-10 and Gata3 in Patients With Lrba Deficiency and Cvid With No Known Monogenic Disease: Association With Disease Severity, Allergologia et Immunopathologia (2019)

32. Molecular Mechanisms of the Action of Vitamin a in Th17/Treg Axis in Multiple Sclerosis, Journal of Molecular Neuroscience (2015)

33. Stat3 Targeting by Polyphenols: Novel Therapeutic Strategy for Melanoma, BioFactors (2017)

34. Oncogenic Virus Infections in the General Population and End-Stage Renal Disease Patients With Special Emphasis on Kaposi’S Sarcoma Associated Herpes Virus (Kshv) in Northeast of Iran, Jundishapur Journal of Microbiology (2015)

35. Il-35, a Double-Edged Sword in Cancer, Journal of Cellular Biochemistry (2020)

36. The Trend in Histological Changes and the Incidence of Esophagus Cancer in Iran (2003–2008), International Journal of Preventive Medicine (2016)

37. The Role of Th1 and Th17 Cells in Glomerulonephritis, Journal of Nephropathology (2015)

38. Application of Nanoparticle Technology in the Treatment of Systemic Lupus Erythematous, Biomedicine and Pharmacotherapy (2016)

39. Unfulfilled Inflammatory Resolution: A Key Factor in the Pathogenesis of Psoriasis, Iranian Journal of Allergy# Asthma and Immunology (2020)

40. Immunopathogenesis of Systemic Lupus Erythematosus, Translational Autoimmunity: Volume 6: Advances in Autoimmune Rheumatic Diseases (2023)

41. Features and Roles of T Helper 9 Cells and Interleukin 9 in Immunological Diseases, Allergologia et Immunopathologia (2019)

42. Immunotherapy in Aml: A Brief Review on Emerging Strategies, Clinical and Translational Oncology (2021)

43. Role of Microbiota-Derived Short-Chain Fatty Acids in Nervous System Disorders, Biomedicine and Pharmacotherapy (2021)

44. Pulmonary Manifestations of Predominantly Antibody Deficiencies, Pulmonary Manifestations of Primary Immunodeficiency Diseases (2018)

45. Multiple Sclerosis Pathogenesis: Missing Pieces of an Old Puzzle, Reviews in the Neurosciences (2019)

46. Immunogenetics of Lupus Erythematosus, Advances in Experimental Medicine and Biology (2022)

47. Common Variable Immunodeficiency: Epidemiology, Pathogenesis, Clinical Manifestations, Diagnosis, Classification, and Management, Journal of Investigational Allergology and Clinical Immunology (2020)

48. Human Development Inequality Index and Cancer Pattern: A Global Distributive Study, Asian Pacific Journal of Cancer Prevention (2016)

49. Licensed Monoclonal Antibodies and Associated Challenges, Human Antibodies (2015)

Style	Citing Format
MLA	Valizadeh A, et al.. "Potential Role of Regulatory B Cells in Immunological Diseases." Immunology Letters, vol. 215, no. , 2019, pp. 48-59.
APA	Valizadeh A, Sanaei R, Rezaei N, Azizi G, Fekrvand S, Aghamohammadi A, Yazdani R (2019). Potential Role of Regulatory B Cells in Immunological Diseases. Immunology Letters, 215(), 48-59.
Chicago	Valizadeh A, Sanaei R, Rezaei N, Azizi G, Fekrvand S, Aghamohammadi A, Yazdani R. "Potential Role of Regulatory B Cells in Immunological Diseases." Immunology Letters 215, no. (2019): 48-59.
Harvard	Valizadeh A et al. (2019) 'Potential Role of Regulatory B Cells in Immunological Diseases', Immunology Letters, 215(), pp. 48-59.
Vancouver	Valizadeh A, Sanaei R, Rezaei N, Azizi G, Fekrvand S, Aghamohammadi A, et al.. Potential Role of Regulatory B Cells in Immunological Diseases. Immunology Letters. 2019;215():48-59.
BibTex	@article{ author = {Valizadeh A and Sanaei R and Rezaei N and Azizi G and Fekrvand S and Aghamohammadi A and Yazdani R}, title = {Potential Role of Regulatory B Cells in Immunological Diseases}, journal = {Immunology Letters}, volume = {215}, number = {}, pages = {48-59}, year = {2019} }
RIS	TY - JOUR AU - Valizadeh A AU - Sanaei R AU - Rezaei N AU - Azizi G AU - Fekrvand S AU - Aghamohammadi A AU - Yazdani R TI - Potential Role of Regulatory B Cells in Immunological Diseases JO - Immunology Letters VL - 215 IS - SP - 48 EP - 59 PY - 2019 ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract