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Effects of the Biological Environment on Ceramics: Degradation, Cell Response, and in Vivo Behavior Publisher



Kargozar S1 ; Hamzehlou S2 ; Baino F3
Authors
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Authors Affiliations
  1. 1. Mashhad University of Medical Sciences, Mashhad, Iran
  2. 2. Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Politecnico di Torino, Turin, Italy

Source: Fundamental Biomaterials: Ceramics Published:2018


Abstract

Bioceramics is an extraordinarily versatile class of specially designed ceramics for the repair and reconstruction of diseased or damaged parts of the body. Based on their response to the biological environment, bioceramics are commonly classified into three major families, i.e., almost-inert (e.g., alumina and zirconia), bioactive (e.g., bioactive glasses and glass-ceramics), and resorbable ceramics (e.g., calcium phosphates). Their behavior in contact with biological fluids, cells, and tissues rules their suitability for a range of applications, which include bearings of joint prostheses, bone fillers, porous scaffolds, and coatings. This chapter discusses the effects of the biological environment on ceramics in the light of available in vitro and in vivo studies. © 2018 Elsevier Ltd. All rights reserved.
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