Solubility of Caffeine in N-Methyl-2-Pyrrolidone + Ethanol Mixture at Different Temperatures

Solubility of Caffeine in N-Methyl-2-Pyrrolidone + Ethanol Mixture at Different Temperatures Publisher

Rezaei H^{1, 2} ; Rahimpour E^{2, 3} ; Ghafourian T⁴ ; Martinez F⁵ ; Barzegarjalali M⁶ ; Jouyban A^{2, 7}

Show Affiliations

1. Student Research Committee, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
2. Pharmaceutical Analysis Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
3. Food and Drug Safety Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
4. School of Life Sciences, University of Sussex, Brighton, BN1 9QG, United Kingdom
5. Grupo de Investigaciones Farmaceutico-Fisicoquimicas, Departamento de Farmacia, Facultad de Ciencias, Universidad Nacional de Colombia â€“ Sede Bogota, Cra. 30 No. 45-03, Bogota, D.C., Colombia
6. Research Center for Pharmaceutical Nanotechnology and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
7. Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Molecular Liquids Published:2020

Abstract

The solubility profile of caffeine in the binary non-aqueous mixtures of N-methyl-2-pyrrolidone (NMP) and ethanol at different temperatures is determined and the obtained data are fitted to some linear and non-linear cosolvency models including the van't Hoff, the double log-log, the mixture response surface, Yalkowsky, Jouyban-Acree, Jouyban-Acree-van't Hoff, and the modified Wilson models. The measured density data of caffeine saturated solutions as another physico-chemical property are also correlated with the Jouyban-Acree model and the results are discussed. In order to investigate the accuracy of the applied models, the mean relative deviations (MRD%) of the back-calculated solubility data is calculated. Furthermore, the apparent thermodynamic properties of caffeine dissolution process are also calculated by using van't Hoff and Gibbs equations. © 2019 Elsevier B.V.

Related Docs

View other Related Docs

1. Solubility of Caffeine in Carbitol + Ethanol Mixture at Different Temperatures, Journal of Molecular Liquids (2020)

2. Solubility of Codeine Phosphate in N-Methyl-2-Pyrrolidone +2-Propanol Mixture at Different Temperatures, Journal of Molecular Liquids (2020)

3. Solubility of Codeine Phosphate in Carbitol + 2-Propanol Mixture at Different Temperatures, Drug Development and Industrial Pharmacy (2020)

4. Solubility of Sildenafil Citrate in the Binary Mixtures of Ethylene Glycol and Water at Different Temperatures, Journal of Molecular Liquids (2020)

5. Mesalazine Solubility in the Binary Mixtures of Ethanol and Water at Various Temperatures, Physics and Chemistry of Liquids (2021)

6. A Laser Monitoring Technique for Determination of Mesalazine Solubility in Propylene Glycol and Ethanol Mixtures at Various Temperatures, Journal of Molecular Liquids (2020)

7. Mesalazine Solubility in Propylene Glycol and Water Mixtures at Various Temperatures Using a Laser Monitoring Technique, Journal of Molecular Liquids (2020)

8. Simulation of Mesalazine Solubility in the Binary Solvents at Various Temperatures, Journal of Molecular Liquids (2022)

Experts (# of related papers)

Alireza Foroumadi (1)

Style	Citing Format
MLA	Rezaei H, et al.. "Solubility of Caffeine in N-Methyl-2-Pyrrolidone + Ethanol Mixture at Different Temperatures." Journal of Molecular Liquids, vol. 300, no. , 2020, pp. -.
APA	Rezaei H, Rahimpour E, Ghafourian T, Martinez F, Barzegarjalali M, Jouyban A (2020). Solubility of Caffeine in N-Methyl-2-Pyrrolidone + Ethanol Mixture at Different Temperatures. Journal of Molecular Liquids, 300(), -.
Chicago	Rezaei H, Rahimpour E, Ghafourian T, Martinez F, Barzegarjalali M, Jouyban A. "Solubility of Caffeine in N-Methyl-2-Pyrrolidone + Ethanol Mixture at Different Temperatures." Journal of Molecular Liquids 300, no. (2020): -.
Harvard	Rezaei H et al. (2020) 'Solubility of Caffeine in N-Methyl-2-Pyrrolidone + Ethanol Mixture at Different Temperatures', Journal of Molecular Liquids, 300(), pp. -.
Vancouver	Rezaei H, Rahimpour E, Ghafourian T, Martinez F, Barzegarjalali M, Jouyban A. Solubility of Caffeine in N-Methyl-2-Pyrrolidone + Ethanol Mixture at Different Temperatures. Journal of Molecular Liquids. 2020;300():-.
BibTex	@article{ author = {Rezaei H and Rahimpour E and Ghafourian T and Martinez F and Barzegarjalali M and Jouyban A}, title = {Solubility of Caffeine in N-Methyl-2-Pyrrolidone + Ethanol Mixture at Different Temperatures}, journal = {Journal of Molecular Liquids}, volume = {300}, number = {}, pages = {-}, year = {2020} }
RIS	TY - JOUR AU - Rezaei H AU - Rahimpour E AU - Ghafourian T AU - Martinez F AU - Barzegarjalali M AU - Jouyban A TI - Solubility of Caffeine in N-Methyl-2-Pyrrolidone + Ethanol Mixture at Different Temperatures JO - Journal of Molecular Liquids VL - 300 IS - SP - EP - PY - 2020 ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract