The Role of Lncrna Mcm3ap-As1 in Human Cancer

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The Role of Lncrna Mcm3ap-As1 in Human Cancer Publisher Pubmed

Azizidoost S¹ ; Ghaedrahmati F² ; Sheykhisabzehpoush M³ ; Uddin S⁴ ; Ghafourian M^{3, 5} ; Mousavi Salehi A³ ; Keivan M⁶ ; Cheraghzadeh M⁷ ; Nazeri Z⁷ ; Farzaneh M⁵ ; Khoshnam SE⁸

Show Affiliations

1. Atherosclerosis Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
2. Department of Immunology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
3. Department of Immunology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
4. Translational Research Institute and Dermatology Institute, Academic Health System, Hamad Medical Corporation, Doha, Qatar
5. Fertility, Infertility and Perinatology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
6. Fertility and Infertility Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran
7. Department of Biochemistry, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
8. Persian Gulf Physiology Research Center, Medical Basic Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Source: Clinical and Translational Oncology Published:2023

Abstract

Long noncoding RNAs (lncRNA) play pivotal roles in every level of gene and genome regulation. MCM3AP-AS1 is a lncRNA that has an oncogenic role in several kinds of cancers. Aberrant expression of MCM3AP-AS1 has been reported to be involved in the progression of diverse malignancies, including colorectal, cervical, prostate, lymphoma, lung, ovary, liver, bone, and breast cancers. It is generally believed that MCM3AP-AS1 expression is associated with cancer cell growth, proliferation, angiogenesis, and metastasis. MCM3AP-AS1 by targeting various signaling pathways and microRNAs (miRNAs) presents an important role in cancer pathogenesis. MCM3AP-AS1 as a competitive endogenous RNA has the ability to sponge miRNA, inhibit their expressions, and bind to different target mRNAs related to cancer development. Therefore, MCM3AP-AS1 by targeting several signaling pathways, including the FOX family, Wnt, EGF, and VEGF can be a potent target for cancer prediction and diagnosis. In this review, we will summarize the role of MCM3AP-AS1 in various human cancers. © 2022, The Author(s), under exclusive licence to Federacion de Sociedades Espanolas de Oncologia (FESEO).

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Style	Citing Format
MLA	Azizidoost S, et al.. "The Role of Lncrna Mcm3ap-As1 in Human Cancer." Clinical and Translational Oncology, vol. 25, no. 1, 2023, pp. 33-47.
APA	Azizidoost S, Ghaedrahmati F, Sheykhisabzehpoush M, Uddin S, Ghafourian M, Mousavi Salehi A, Keivan M, Cheraghzadeh M, Nazeri Z, Farzaneh M, Khoshnam SE (2023). The Role of Lncrna Mcm3ap-As1 in Human Cancer. Clinical and Translational Oncology, 25(1), 33-47.
Chicago	Azizidoost S, Ghaedrahmati F, Sheykhisabzehpoush M, Uddin S, Ghafourian M, Mousavi Salehi A, Keivan M, et al.. "The Role of Lncrna Mcm3ap-As1 in Human Cancer." Clinical and Translational Oncology 25, no. 1 (2023): 33-47.
Harvard	Azizidoost S et al. (2023) 'The Role of Lncrna Mcm3ap-As1 in Human Cancer', Clinical and Translational Oncology, 25(1), pp. 33-47.
Vancouver	Azizidoost S, Ghaedrahmati F, Sheykhisabzehpoush M, Uddin S, Ghafourian M, Mousavi Salehi A, et al.. The Role of Lncrna Mcm3ap-As1 in Human Cancer. Clinical and Translational Oncology. 2023;25(1):33-47.
BibTex	@article{ author = {Azizidoost S and Ghaedrahmati F and Sheykhisabzehpoush M and Uddin S and Ghafourian M and Mousavi Salehi A and Keivan M and Cheraghzadeh M and Nazeri Z and Farzaneh M and Khoshnam SE}, title = {The Role of Lncrna Mcm3ap-As1 in Human Cancer}, journal = {Clinical and Translational Oncology}, volume = {25}, number = {1}, pages = {33-47}, year = {2023} }
RIS	TY - JOUR AU - Azizidoost S AU - Ghaedrahmati F AU - Sheykhisabzehpoush M AU - Uddin S AU - Ghafourian M AU - Mousavi Salehi A AU - Keivan M AU - Cheraghzadeh M AU - Nazeri Z AU - Farzaneh M AU - Khoshnam SE TI - The Role of Lncrna Mcm3ap-As1 in Human Cancer JO - Clinical and Translational Oncology VL - 25 IS - 1 SP - 33 EP - 47 PY - 2023 ER -

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