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A Review on Expression and Regulatory Mechanisms of Mir-337-3P in Cancer Publisher Pubmed



Yarahmadi G1 ; Tavakoli Ataabadi S2 ; Dashti Z1, 3 ; Dehghanian M4
Authors
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Authors Affiliations
  1. 1. Department of Medical Genetics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
  2. 2. Department of Medical Genetics School of Medicine, Iran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Genetics, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences Campus, Yazd, Iran
  4. 4. Department of Genetics and Molecular Biology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Biomolecular Structure and Dynamics Published:2024


Abstract

A group of diseases generally referred to as cancer represents a serious threat to people’s health all over the world and has a significant negative influence on every aspect of the lives of patients. The development of cancer is influenced by several environmental, genetic, and epigenetic factors. MicroRNAs (miRNAs), a class of non-coding RNAs, can alter the expression of genes involved in cell proliferation, migration, metastasis, and apoptosis, lead to the pathogenesis of cancer. Additionally, several effectors modify miRNAs directly, including methylation, circular RNAs, and long non-coding RNAs (lncRNAs). In this review, we have explained the role of mir-337-3p in the pathways related to the pathogenesis of different cancers. Studying the functional role of miR-337-3p is necessary for detecting novel molecules as tumor markers and discovering novel targets for cancer treatment. Communicated by Ramaswamy H. Sarma. © 2024 Informa UK Limited, trading as Taylor & Francis Group.
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