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Molecular Evidence of Role of Vitamin D Deficiency in Various Extraskeletal Diseases Publisher Pubmed



Zendehdel A1 ; Arefi M2
Authors
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Authors Affiliations
  1. 1. Department of Geriatric Medicine, Ziaeian Hospital, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Clinical Toxicology, School of Medicine, Baharloo Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Cellular Biochemistry Published:2019


Abstract

Background: Role of vitamin D is not only limited to skeletal system but various other systems of the body, such as immune system, endocrine system, and cardiopulmonary system. Materials and Methods: It is supported by the confirmations of systems-wide expression of vitamin D receptor (VDR), endocrinal effect of calcitriol, and its role in immune responses. Results: Expression of VDR in various systems, immunoregulatory and hormonal response of vitamin D and deficiency of vitamin D may establish various pathologies in the body. Conclusion: This review provides molecular evidence of relation of vitamin D with extra skeletal. © 2019 Wiley Periodicals, Inc.
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