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Synthesis of New Benzo[F]Imidazo[1,2-D][1,4]Oxazepines: Agno3-Mediated Intramolecular Hydroamination Publisher



Mahdavi M1 ; Hariri R2 ; Saeedi M3, 4 ; Foroumadi A1 ; Shafiee A1 ; Akbarzadeh T2, 4
Authors
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Authors Affiliations
  1. 1. Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Persian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Tetrahedron Letters Published:2015


Abstract

Novel benzo[f]imidazo[1,2-d][1,4]oxazepine derivatives were synthesized from [4,5-diaryl-2-(2-(prop-2-yn-1-yloxy)aryl)-1H-imidazoles] by a AgNO3-promoted 7-exo-dig hydroamination proceeding in DMF at 80 °C. © 2015 Elsevier Ltd. All rights reserved.