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Agarose-Based Biomaterials for Tissue Engineering Publisher Pubmed



Zarrintaj P1 ; Manouchehri S1 ; Ahmadi Z2 ; Saeb MR3 ; Urbanska AM4 ; Kaplan DL5 ; Mozafari M6, 7, 8
Authors
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Authors Affiliations
  1. 1. School of Chemical Engineering, College of Engineering, University of Tehran, Tehran, Iran
  2. 2. Department of Chemistry, Amirkabir University of Technology, Tehran, Iran
  3. 3. Department of Resin and Additives, Institute for Color Science and Technology, P.O. Box: 16765-654, Tehran, Iran
  4. 4. Department of Medicine, Columbia University Medical Center, New York, NY, United States
  5. 5. Department of Biomedical Engineering, Tufts University, Medford, 02155, MA, United States
  6. 6. Bioengineering Research Group, Nanotechnology and Advanced Materials Department, Materials and Energy Research Center (MERC), Tehran, Iran
  7. 7. Cellular and Molecular Research Center, Iran University of Medical Sciences (IUMS), Tehran, Iran
  8. 8. Department of Tissue Engineering & Regenerative Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran

Source: Carbohydrate Polymers Published:2018


Abstract

Agarose is a natural polysaccharide polymer having unique characteristics that give reason to consider it for tissue engineering applications. Special characteristics of agarose such as its excellent biocompatibility, thermo-reversible gelation behavior and physiochemical features support its use as a biomaterial for cell growth and/or controlled/localized drug delivery. The resemblance of this natural carbohydrate polymer to the extracellular matrix results in attractive features that bring about a strong interest in its usage in the field. The scope of this review is to summarize the extensive researches addressing agarose-based biomaterials in order to provide an in-depth understanding of its tissue engineering-related applications. © 2018 Elsevier Ltd
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