The Comparison of Clinical, Laboratory, and Radiological Findings in Immunocompromised and Immunocompetent Patients With Covid-19: A Case-Control Study

The Comparison of Clinical, Laboratory, and Radiological Findings in Immunocompromised and Immunocompetent Patients With Covid-19: A Case-Control Study Publisher Pubmed

Abasian L¹ ; Jafari F¹ ; Seyedalinaghi S² ; Ayoobi Yazdi N³ ; Daraei M⁴ ; Ahmadinejad N³ ; Ghiasvand F¹ ; Khalili H¹ ; Seifi A¹ ; Maydani M¹ ; Behnezhad F⁵ ; Ahmadinejad Z⁶

Source: Immunity# Inflammation and Disease Published:2023

Abstract

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19) with significant morbidity and mortality. We reported and compared the clinical and para-clinical findings of immunocompromised and immunocompetent COVID-19 patients in a case-control study at the Imam Khomeini hospital in Tehran, Iran. Methods: In this study, 107 immunocompromised COVID-19 patients were recruited as the case group, and 107 immunocompetent COVID-19 patients as the control group. The participants were matched based on age and sex. The patients' information was retrieved from the hospital records in an information sheet. Associations between clinical and para-clinical findings with the immune status were assessed using bivariate and multivariate analyses. Results: The initial pulse rate and recovery time were significantly higher in immunocompromised patients (p <.05). Myalgia, nausea/vomiting, loss of appetite, headache, and dizziness were more frequently reported by the control group (p <.05). Regarding the prescribed medications' duration, Sofosbovir was used longer in the case group, while Ribavirin was used longer in the control groups (p <.05). The most common complication in the case group was acute respiratory distress syndrome, although no major complications were observed in the control group. According to the multivariate analysis, recovery time and Lopinavir/Ritonavir (Kaletra) prescription were significantly higher in the immunocompromised compared to the immunocompetent group. Conclusion: Recovery time was significantly longer in the immunocompromised compared to the immunocompetent group, which emphasizes the necessity of prolonged care in these high-risk patients. Also, it is recommended to investigate the effect of novel therapeutic interventions to reduce the recovery time in addition to improving the prognosis of immunodeficient patients with COVID-19. © 2023 The Authors. Immunity, Inflammation and Disease published by John Wiley & Sons Ltd.

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Style	Citing Format
MLA	Abasian L, et al.. "The Comparison of Clinical, Laboratory, and Radiological Findings in Immunocompromised and Immunocompetent Patients With Covid-19: A Case-Control Study." Immunity# Inflammation and Disease, vol. 11, no. 4, 2023, pp. -.
APA	Abasian L, Jafari F, Seyedalinaghi S, Ayoobi Yazdi N, Daraei M, Ahmadinejad N, Ghiasvand F, Khalili H, Seifi A, Maydani M, Behnezhad F, Ahmadinejad Z (2023). The Comparison of Clinical, Laboratory, and Radiological Findings in Immunocompromised and Immunocompetent Patients With Covid-19: A Case-Control Study. Immunity# Inflammation and Disease, 11(4), -.
Chicago	Abasian L, Jafari F, Seyedalinaghi S, Ayoobi Yazdi N, Daraei M, Ahmadinejad N, Ghiasvand F, et al.. "The Comparison of Clinical, Laboratory, and Radiological Findings in Immunocompromised and Immunocompetent Patients With Covid-19: A Case-Control Study." Immunity# Inflammation and Disease 11, no. 4 (2023): -.
Harvard	Abasian L et al. (2023) 'The Comparison of Clinical, Laboratory, and Radiological Findings in Immunocompromised and Immunocompetent Patients With Covid-19: A Case-Control Study', Immunity# Inflammation and Disease, 11(4), pp. -.
Vancouver	Abasian L, Jafari F, Seyedalinaghi S, Ayoobi Yazdi N, Daraei M, Ahmadinejad N, et al.. The Comparison of Clinical, Laboratory, and Radiological Findings in Immunocompromised and Immunocompetent Patients With Covid-19: A Case-Control Study. Immunity# Inflammation and Disease. 2023;11(4):-.
BibTex	@article{ author = {Abasian L and Jafari F and Seyedalinaghi S and Ayoobi Yazdi N and Daraei M and Ahmadinejad N and Ghiasvand F and Khalili H and Seifi A and Maydani M and Behnezhad F and Ahmadinejad Z}, title = {The Comparison of Clinical, Laboratory, and Radiological Findings in Immunocompromised and Immunocompetent Patients With Covid-19: A Case-Control Study}, journal = {Immunity# Inflammation and Disease}, volume = {11}, number = {4}, pages = {-}, year = {2023} }
RIS	TY - JOUR AU - Abasian L AU - Jafari F AU - Seyedalinaghi S AU - Ayoobi Yazdi N AU - Daraei M AU - Ahmadinejad N AU - Ghiasvand F AU - Khalili H AU - Seifi A AU - Maydani M AU - Behnezhad F AU - Ahmadinejad Z TI - The Comparison of Clinical, Laboratory, and Radiological Findings in Immunocompromised and Immunocompetent Patients With Covid-19: A Case-Control Study JO - Immunity# Inflammation and Disease VL - 11 IS - 4 SP - EP - PY - 2023 ER -

Style

Citing Format

MLA

Abasian L, et al.. "The Comparison of Clinical, Laboratory, and Radiological Findings in Immunocompromised and Immunocompetent Patients With Covid-19: A Case-Control Study." Immunity# Inflammation and Disease, vol. 11, no. 4, 2023, pp. -.

APA

Abasian L, Jafari F, Seyedalinaghi S, Ayoobi Yazdi N, Daraei M, Ahmadinejad N, Ghiasvand F, Khalili H, Seifi A, Maydani M, Behnezhad F, Ahmadinejad Z (2023). The Comparison of Clinical, Laboratory, and Radiological Findings in Immunocompromised and Immunocompetent Patients With Covid-19: A Case-Control Study. Immunity# Inflammation and Disease, 11(4), -.

Chicago

Abasian L, Jafari F, Seyedalinaghi S, Ayoobi Yazdi N, Daraei M, Ahmadinejad N, Ghiasvand F, et al.. "The Comparison of Clinical, Laboratory, and Radiological Findings in Immunocompromised and Immunocompetent Patients With Covid-19: A Case-Control Study." Immunity# Inflammation and Disease 11, no. 4 (2023): -.

Harvard

Abasian L et al. (2023) 'The Comparison of Clinical, Laboratory, and Radiological Findings in Immunocompromised and Immunocompetent Patients With Covid-19: A Case-Control Study', Immunity# Inflammation and Disease, 11(4), pp. -.

Vancouver

Abasian L, Jafari F, Seyedalinaghi S, Ayoobi Yazdi N, Daraei M, Ahmadinejad N, et al.. The Comparison of Clinical, Laboratory, and Radiological Findings in Immunocompromised and Immunocompetent Patients With Covid-19: A Case-Control Study. Immunity# Inflammation and Disease. 2023;11(4):-.

BibTex

@article{ author = {Abasian L and Jafari F and Seyedalinaghi S and Ayoobi Yazdi N and Daraei M and Ahmadinejad N and Ghiasvand F and Khalili H and Seifi A and Maydani M and Behnezhad F and Ahmadinejad Z}, title = {The Comparison of Clinical, Laboratory, and Radiological Findings in Immunocompromised and Immunocompetent Patients With Covid-19: A Case-Control Study}, journal = {Immunity# Inflammation and Disease}, volume = {11}, number = {4}, pages = {-}, year = {2023} }

RIS

TY - JOUR
AU - Abasian L
AU - Jafari F
AU - Seyedalinaghi S
AU - Ayoobi Yazdi N
AU - Daraei M
AU - Ahmadinejad N
AU - Ghiasvand F
AU - Khalili H
AU - Seifi A
AU - Maydani M
AU - Behnezhad F
AU - Ahmadinejad Z
TI - The Comparison of Clinical, Laboratory, and Radiological Findings in Immunocompromised and Immunocompetent Patients With Covid-19: A Case-Control Study
JO - Immunity# Inflammation and Disease
VL - 11
IS - 4
SP -
EP -
PY - 2023
ER -

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