Collagen Coated Electrospun Polyethersulfon Nanofibers Improved Insulin Producing Cells Differentiation Potential of Human Induced Pluripotent Stem Cells

Collagen Coated Electrospun Polyethersulfon Nanofibers Improved Insulin Producing Cells Differentiation Potential of Human Induced Pluripotent Stem Cells Publisher Pubmed

Mansour RN¹ ; Soleimanifar F² ; Abazari MF³ ; Torabinejad S³ ; Ardeshirylajimi A^{4, 5} ; Ghoraeian P³ ; Mousavi SA⁶ ; Sharif Rahmani E⁷ ; Hassannia H^{8, 9} ; Enderami SE¹

Show Affiliations

1. Stem Cell Technology Research Center, Tehran, Iran
2. Dietary Supplements and Probiotic Research Center, Alborz University of Medical Sciences, Karaj, Iran
3. Department of Genetics, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran
4. Urogenital Stem Cell Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
5. Department of Tissue Engineering and Applied Cell Sciences, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
6. Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran
7. Department of Medical Biotechnology, School of Allied Medicine, Iran University of Medical Science, Tehran, Iran
8. Amol Faculty of Paramedical Sciences, Mazandaran University of Medical Sciences, Sari, Iran
9. Immunogenetic Research Center, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran

Source: Artificial Cells# Nanomedicine and Biotechnology Published:2018

Abstract

Given the current conditions of life, one of the problems that the world is facing and is rapidly expanding is diabetes. The existing treatment methods are not responsive to these patients. Today, due to the advent of tissue engineering, cell and stem cell therapies, there are many hopes for treating these patients. In the present study, Polyethersulfone (PES) nanofibers were fabricated by electrospinning and then coated by collagen (PES-collagen), since this protein is abundant at the pancreatic extracellular matrix. After scaffold characterization, pancreatic differentiation potential of human induced pluripotent stem cells (hiPSCs) was investigated when cultured on PES-collagen by RT-qPCR, Immunofluorescence staining and insulin and C-peptide release assays. Pancreatic genes and proteins in cultured iPSCs on PES-collagen were expressed significantly higher than those cultured on culture plate as 2 D control group. Although differentiated cells in both groups are functional and secrete C-peptide and insulin in response to glucose challenges according to the immunoassay result. Considered together, PES-collagen demonstrated that it can be effective during pancreatic differentiation of the stem cells and can also be considered as a promising candidate for use in pancreatic tissue engineering application. © 2018, © 2018 Informa UK Limited, trading as Taylor & Francis Group.

Related Docs

View other Related Docs

1. Pcl/Pva Nanofibrous Scaffold Improve Insulin-Producing Cells Generation From Human Induced Pluripotent Stem Cells, Gene (2018)

2. Generation of High Yield Insulin-Producing Cells (Ipcs) From Various Sources of Stem Cells, Vitamins and Hormones (2021)

3. Generation of High-Yield Insulin Producing Cells From Human-Induced Pluripotent Stem Cells on Polyethersulfone Nanofibrous Scaffold, Artificial Cells# Nanomedicine and Biotechnology (2018)

4. Three-Dimensional Nanofiberous Plla/Pcl Scaffold Improved Biochemical and Molecular Markers Hips Cell-Derived Insulin-Producing Islet-Like Cells, Artificial Cells# Nanomedicine and Biotechnology (2018)

5. Generation of Insulin-Producing Cells From Human Induced Pluripotent Stem Cells on Plla/Pva Nanofiber Scaffold, Artificial Cells# Nanomedicine and Biotechnology (2018)

6. The Role of Micrornas in the Induction of Pancreatic Differentiation, Current Stem Cell Research and Therapy (2020)

7. A Novel Silk/Pes Hybrid Nanofibrous Scaffold Promotes the in Vitro Proliferation and Differentiation of Adipose-Derived Mesenchymal Stem Cells Into Insulin Producing Cells, Polymers for Advanced Technologies (2020)

8. Phbv Nanofibers Promotes Insulin-Producing Cells Differentiation of Human Induced Pluripotent Stem Cells, Gene (2021)

Experts (# of related papers)

View all Related Experts

Somayeh Ebrahimi Barough (2)

Esmaeil Sadroddiny (2)

Style	Citing Format
MLA	Mansour RN, et al.. "Collagen Coated Electrospun Polyethersulfon Nanofibers Improved Insulin Producing Cells Differentiation Potential of Human Induced Pluripotent Stem Cells." Artificial Cells# Nanomedicine and Biotechnology, vol. 46, no. sup3, 2018, pp. S734-S739.
APA	Mansour RN, Soleimanifar F, Abazari MF, Torabinejad S, Ardeshirylajimi A, Ghoraeian P, Mousavi SA, Sharif Rahmani E, Hassannia H, Enderami SE (2018). Collagen Coated Electrospun Polyethersulfon Nanofibers Improved Insulin Producing Cells Differentiation Potential of Human Induced Pluripotent Stem Cells. Artificial Cells# Nanomedicine and Biotechnology, 46(sup3), S734-S739.
Chicago	Mansour RN, Soleimanifar F, Abazari MF, Torabinejad S, Ardeshirylajimi A, Ghoraeian P, Mousavi SA, Sharif Rahmani E, Hassannia H, Enderami SE. "Collagen Coated Electrospun Polyethersulfon Nanofibers Improved Insulin Producing Cells Differentiation Potential of Human Induced Pluripotent Stem Cells." Artificial Cells# Nanomedicine and Biotechnology 46, no. sup3 (2018): S734-S739.
Harvard	Mansour RN et al. (2018) 'Collagen Coated Electrospun Polyethersulfon Nanofibers Improved Insulin Producing Cells Differentiation Potential of Human Induced Pluripotent Stem Cells', Artificial Cells# Nanomedicine and Biotechnology, 46(sup3), pp. S734-S739.
Vancouver	Mansour RN, Soleimanifar F, Abazari MF, Torabinejad S, Ardeshirylajimi A, Ghoraeian P, et al.. Collagen Coated Electrospun Polyethersulfon Nanofibers Improved Insulin Producing Cells Differentiation Potential of Human Induced Pluripotent Stem Cells. Artificial Cells# Nanomedicine and Biotechnology. 2018;46(sup3):S734-S739.
BibTex	@article{ author = {Mansour RN and Soleimanifar F and Abazari MF and Torabinejad S and Ardeshirylajimi A and Ghoraeian P and Mousavi SA and Sharif Rahmani E and Hassannia H and Enderami SE}, title = {Collagen Coated Electrospun Polyethersulfon Nanofibers Improved Insulin Producing Cells Differentiation Potential of Human Induced Pluripotent Stem Cells}, journal = {Artificial Cells# Nanomedicine and Biotechnology}, volume = {46}, number = {sup3}, pages = {S734-S739}, year = {2018} }
RIS	TY - JOUR AU - Mansour RN AU - Soleimanifar F AU - Abazari MF AU - Torabinejad S AU - Ardeshirylajimi A AU - Ghoraeian P AU - Mousavi SA AU - Sharif Rahmani E AU - Hassannia H AU - Enderami SE TI - Collagen Coated Electrospun Polyethersulfon Nanofibers Improved Insulin Producing Cells Differentiation Potential of Human Induced Pluripotent Stem Cells JO - Artificial Cells# Nanomedicine and Biotechnology VL - 46 IS - sup3 SP - S734 EP - S739 PY - 2018 ER -

Style

Citing Format

MLA

Mansour RN, et al.. "Collagen Coated Electrospun Polyethersulfon Nanofibers Improved Insulin Producing Cells Differentiation Potential of Human Induced Pluripotent Stem Cells." Artificial Cells# Nanomedicine and Biotechnology, vol. 46, no. sup3, 2018, pp. S734-S739.

APA

Mansour RN, Soleimanifar F, Abazari MF, Torabinejad S, Ardeshirylajimi A, Ghoraeian P, Mousavi SA, Sharif Rahmani E, Hassannia H, Enderami SE (2018). Collagen Coated Electrospun Polyethersulfon Nanofibers Improved Insulin Producing Cells Differentiation Potential of Human Induced Pluripotent Stem Cells. Artificial Cells# Nanomedicine and Biotechnology, 46(sup3), S734-S739.

Chicago

Mansour RN, Soleimanifar F, Abazari MF, Torabinejad S, Ardeshirylajimi A, Ghoraeian P, Mousavi SA, Sharif Rahmani E, Hassannia H, Enderami SE. "Collagen Coated Electrospun Polyethersulfon Nanofibers Improved Insulin Producing Cells Differentiation Potential of Human Induced Pluripotent Stem Cells." Artificial Cells# Nanomedicine and Biotechnology 46, no. sup3 (2018): S734-S739.

Harvard

Mansour RN et al. (2018) 'Collagen Coated Electrospun Polyethersulfon Nanofibers Improved Insulin Producing Cells Differentiation Potential of Human Induced Pluripotent Stem Cells', Artificial Cells# Nanomedicine and Biotechnology, 46(sup3), pp. S734-S739.

Vancouver

Mansour RN, Soleimanifar F, Abazari MF, Torabinejad S, Ardeshirylajimi A, Ghoraeian P, et al.. Collagen Coated Electrospun Polyethersulfon Nanofibers Improved Insulin Producing Cells Differentiation Potential of Human Induced Pluripotent Stem Cells. Artificial Cells# Nanomedicine and Biotechnology. 2018;46(sup3):S734-S739.

BibTex

@article{ author = {Mansour RN and Soleimanifar F and Abazari MF and Torabinejad S and Ardeshirylajimi A and Ghoraeian P and Mousavi SA and Sharif Rahmani E and Hassannia H and Enderami SE}, title = {Collagen Coated Electrospun Polyethersulfon Nanofibers Improved Insulin Producing Cells Differentiation Potential of Human Induced Pluripotent Stem Cells}, journal = {Artificial Cells# Nanomedicine and Biotechnology}, volume = {46}, number = {sup3}, pages = {S734-S739}, year = {2018} }

RIS

TY - JOUR
AU - Mansour RN
AU - Soleimanifar F
AU - Abazari MF
AU - Torabinejad S
AU - Ardeshirylajimi A
AU - Ghoraeian P
AU - Mousavi SA
AU - Sharif Rahmani E
AU - Hassannia H
AU - Enderami SE
TI - Collagen Coated Electrospun Polyethersulfon Nanofibers Improved Insulin Producing Cells Differentiation Potential of Human Induced Pluripotent Stem Cells
JO - Artificial Cells# Nanomedicine and Biotechnology
VL - 46
IS - sup3
SP - S734
EP - S739
PY - 2018
ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract