Tehran University of Medical Sciences

Science Communicator Platform

Faculty Members have conducted research related to the Development and Characterization of Nanoliposomal Hydroxyurea Against Bt-474 Breast Cancer Cells
Somayeh Handali
Somayeh Handali

Assistant Professor of Pharmaceutical Nanotechnology

Medical Biomaterials Research Center

Tehran University of Medical Sciences

All Documents
1. Eicosapentaenoic Acid As a Bioactive Liquid Lipid in Methotrexate-Loaded Nanostructured Lipid Carriers, Jundishapur Journal of Natural Pharmaceutical Products (2026)
2. Electrochemiluminescence Immunoassay for Point-Of-Care Detection of Cardiac Troponin I Using Hexagonal Ag Nanoparticles and a Multiplexed Screen-Printed Electrode Platform, Journal of Electroanalytical Chemistry (2026)
3. Local Delivery of Linezolid Via Chitosan-Gelatin Hydrogel Coated Orthopedic Implants As a Promising Strategy for Treatment of Implant-Associated Infections, International Journal of Biological Macromolecules (2026)
4. Scalable Multistage Microfluidic Platform for One-Pot Synthesis and Optimization of Drug-Loaded Magnetic Nanoparticles in Cancer Treatment, Journal of Industrial and Engineering Chemistry (2026)
5. Development of Propranolol Loaded Sln for Transdermal Delivery: In-Vitro Characterization and Skin Deposition Studies, Therapeutic Delivery (2025)
6. Fabrication of Crosslinker-Free Chitosan-Hpmc Hydrogel for Implant Coating: A New Approach for the Treatment of Osteomyelitis, Journal of Drug Targeting (2025)
7. The Prospect of Using Nanotechnology to Prevent and Treat Infections Caused by Listeria Monocytogenes, Critical Reviews in Microbiology (2025)
8. The Role of Mitochondrial Dysfunction in the Cytotoxic Synergistic Effect of Gemcitabine and Arsenic on Breast Cancer, PLoS ONE (2025)
9. A Novel Mucoadhesive Film Containing Probiotic Extract for Oral Candidiasis Treatment: Formulation and Antifungal Evaluation, Microbial Pathogenesis (2024)
10. Aptamer-Decorated Nanocarriers for Viral Adsorption: A Special Look at Covid-19, Molecular Therapy Nucleic Acids (2024)
11. Clinical Evaluation of Liposome-Based Gel Formulation Containing Glycolic Acid for the Treatment of Photodamaged Skin, Journal of Drug Targeting (2024)
12. Functionalized Liposomes As a Potential Drug Delivery Systems for Colon Cancer Treatment: A Systematic Review, International Journal of Biological Macromolecules (2024)
13. General Justification in Terms of Effectiveness and Toxicities for the Use of Nanocarriers, Journal of Nanoparticle Research (2023)
14. Nanomedicine “New Food for an Old Mouth”: Novel Approaches for the Treatment of Covid-19, Drug Delivery Letters (2023)
15. Targeted Solid Lipid Nanoparticles Formulation for Colon Cancer Treatment and Cytotoxicity Assessment Using Ht29 Cell Line, Jundishapur Journal of Natural Pharmaceutical Products (2023)
16. What We Need to Know About Liposomes As Drug Nanocarriers: An Updated Review, Advanced Pharmaceutical Bulletin (2023)
17. Functionalized Liposomes As Drug Nanocarriers for Active Targeted Cancer Therapy: A Systematic Review, Journal of Liposome Research (2022)
18. Nanoencapsulation of Aptamer-Functionalized 5-Fluorouracil Liposomes Using Alginate/Chitosan Complex As a Novel Targeting Strategy for Colon-Specific Drug Delivery, Journal of Drug Delivery Science and Technology (2022)
19. Arsenic and Weight Loss: At a Crossroad Between Lipogenesis and Lipolysis, Journal of Trace Elements in Medicine and Biology (2021)
20. Bacteria and Archaea: A New Era of Cancer Therapy, Journal of Controlled Release (2021)
21. Mitochondria and Cancer Therapy, Mitochondrial Metabolism: An Approach to Disease Management (2021)
22. Mitochondria As Balancers of Reduction/Oxidation for Intracellular Environment, Mitochondrial Metabolism: An Approach to Disease Management (2021)
23. Mitotherapy, an Attractive Avenue for the Future Medicine, Mitochondrial Metabolism: An Approach to Disease Management (2021)
24. Nanomedicine and Chemotherapeutics Drug Delivery: Challenges and Opportunities, Journal of Drug Targeting (2021)
25. Interlink Between Improved Formulations, Inhibitory Concentrations and Cell Death Mechanism Investigations of Cytotoxic Drugs: What Really Matters?, Journal of Controlled Release (2020)
26. Phbv/Plga Nanoparticles for Enhanced Delivery of 5-Fluorouracil As Promising Treatment of Colon Cancer, Pharmaceutical Development and Technology (2020)
27. Synergistic Effect of Self-Assembled Curcumin and Piperine Co-Loaded Human Serum Albumin Nanoparticles on Suppressing Cancer Cells, Drug Development and Industrial Pharmacy (2020)
28. A Novel Method for the Simultaneous Determination of 5-Fluorouracil and Oxaliplatin in New Biodegradable Phbv/Plga Nanoparticles, Journal of the Iranian Chemical Society (2019)
29. Co-Delivery of 5-Fluorouracil and Oxaliplatin in Novel Poly(3-Hydroxybutyrate-Co-3-Hydroxyvalerate Acid)/Poly(Lactic-Co-Glycolic Acid) Nanoparticles for Colon Cancer Therapy, International Journal of Biological Macromolecules (2019)
30. New Folate Receptor Targeted Nano Liposomes for Delivery of 5-Fluorouracil to Cancer Cells: Strong Implication for Enhanced Potency and Safety, Life Sciences (2019)
31. Preparation and Evaluation of Matrix Containing Lidocaine and Prilocaine for Using in Transdermal Films, Journal of Reports in Pharmaceutical Sciences (2019)
32. A Mechanistic Study of the Effect of Transferrin Conjugation on Cytotoxicity of Targeted Liposomes, Journal of Microencapsulation (2018)
33. A Novel 5-Fluorouracil Targeted Delivery to Colon Cancer Using Folic Acid Conjugated Liposomes, Biomedicine and Pharmacotherapy (2018)
34. Effects of Coating Layer and Release Medium on Release Profile From Coated Capsules With Eudragit Fs 30D: An in Vitro and in Vivo Study, Drug Development and Industrial Pharmacy (2018)
35. Folic Acid-Modified Liposomal Drug Delivery Strategy for Tumor Targeting of 5-Fluorouracil, European Journal of Pharmaceutical Sciences (2018)
36. In Vitro and in Vivo Evaluation of Coated Capsules for Colonic Delivery, Journal of Drug Delivery Science and Technology (2018)
37. In Vivo Evaluation of Ph and Time-Dependent Polymers As Coating Agent for Colonic Delivery Using Central Composite Design, Journal of Drug Delivery Science and Technology (2018)
38. Transferrin Targeted Liposomal 5-Fluorouracil Induced Apoptosis Via Mitochondria Signaling Pathway in Cancer Cells, Life Sciences (2018)