Isfahan University of Medical Sciences

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Faculty Members have conducted research related to the Drug Repositioning Approach to Target Viral and Host Cells in Terms of Covid-19 Treatment: A Review of in Vivo Experiments and Clinical Studies
Laleh Shariati
Laleh Shariati

Assistant Professor of Molecular Medicine

Department of Biomaterials, Nanotechnology and Tissue Engineering, School of Advanced Medical Technology

Biosensor Research Center

Isfahan University of Medical Sciences

All Documents
1. Evaluation of the Effects of Cartilage Decellularized Ecm in Optimizing Phb-Chitosan-Hnt/Chitosan-Ecm Core-Shell Electrospun Scaffold: Physicochemical and Biological Properties, Biomaterials Advances (2025)
2. Advances in Bioengineered Car T/Nk Cell Therapy for Glioblastoma: Overcoming Immunosuppression and Nanotechnology-Based Strategies for Enhanced Car T/Nk Cell Therapy, Bioengineering and Translational Medicine (2024)
3. Coaxial Electrospun Pgs/Pcl and Pgs/Pgs-Pcl Nanofibrous Membrane Containing Platelet-Rich Plasma for Skin Tissue Engineering, Journal of Biomaterials Science, Polymer Edition (2024)
4. Enhanced Wound Regeneration by Pgs/Pla Fiber Dressing Containing Platelet-Rich Plasma: An in Vitro Study, Scientific Reports (2024)
5. Evaluating the Osteogenic Properties of Polyhydroxybutyrate-Zein/Multiwalled Carbon Nanotubes (Mwcnts) Electrospun Composite Scaffold for Bone Tissue Engineering Applications, International Journal of Biological Macromolecules (2024)
6. Exploring the Potential of Pomegranate (Punica Granatum) Peel Extract and Punicalagin As Novel Anti-Hypercholesterolemic Agents, Functional Foods in Health and Disease (2024)
7. Fabrication of a Tri-Layer Scaffold With Dual Release of Heparin and Prp for Tissue Engineering of Small‐Diameter Blood Vessels, International Journal of Polymeric Materials and Polymeric Biomaterials (2024)
8. Mxene Nanoconfinement of Sam-Modified Molecularly Imprinted Electrochemical Biosensor for Point-Of-Care Monitoring of Carcinoembryonic Antigen, ACS Sensors (2024)
9. Precision in Cancer Diagnostics: Ultra-Sensitive Detection of Mcf-7 Breast Cancer Cells by Gold Nanostructure-Enhanced Electrochemical Biosensing, Journal of Materials Chemistry B (2024)
10. Smart Co-Delivery of Plasmid Dna and Doxorubicin Using Mcm-Chitosan-Peg Polymerization Functionalized With Muc-1 Aptamer Against Breast Cancer, Biomedicine and Pharmacotherapy (2024)
11. A Comprehensive Review on Novel Targeted Therapy Methods and Nanotechnology-Based Gene Delivery Systems in Melanoma, European Journal of Pharmaceutical Sciences (2023)
12. Advances in Nanobased Platforms for Cardiovascular Diseases: Early Diagnosis, Imaging, Treatment, and Tissue Engineering, Environmental Research (2023)
13. An Insight Into Fluorescence and Magnetic Resonance Bioimaging Using a Multifunctional Polyethyleneimine-Passivated Gadocarbon Dots Nanoconstruct Assembled With As1411, Microchimica Acta (2023)
14. Corrigendum to “Exploring the Evolution of Tissue Engineering Strategies Over the Past Decade: From Cell-Based Strategies to Gene-Activated Matrix” [Alex. Eng. J. 81 (2023) 137–169, (S1110016823007755), (10.1016/J.Aej.2023.08.080)], Alexandria Engineering Journal (2023)
15. Crosstalk of Transcriptional Regulators of Adaptive Immune System and Micrornas: An Insight Into Differentiation and Development, Cells (2023)
16. Exploring the Evolution of Tissue Engineering Strategies Over the Past Decade: From Cell-Based Strategies to Gene-Activated Matrix, Alexandria Engineering Journal (2023)
17. Fluorescence Anisotropy Cytosensing of Folate Receptor Positive Tumor Cells Using 3D Polyurethane-Go-Foams Modified With Folic Acid: Molecular Dynamics and in Vitro Studies, Microchimica Acta (2023)
18. Gene Network Analysis of Oxaliplatin-Resistant Colorectal Cancer to Target a Crucial Gene Using Chitosan/Hyaluronic Acid/Protamine Polyplexes Containing Crispr-Cas9, Biochimica et Biophysica Acta - General Subjects (2023)
19. Smartphone-Assisted Lab-In-A-Tube Device Using Gold Nanocluster-Based Aptasensor for Detection of Muc1-Overexpressed Tumor Cells, Analytica Chimica Acta (2023)
20. The Molecular Perspective on the Melanoma and Genome Engineering of T-Cells in Targeting Therapy, Environmental Research (2023)
21. The Potential Therapeutic Impacts of Trehalose on Cardiovascular Diseases As the Environmental-Influenced Disorders: An Overview of Contemporary Findings, Environmental Research (2023)
22. Association of Clinical Features With Spike Glycoprotein Mutations in Iranian Covid-19 Patients, Journal of Clinical Medicine (2022)
23. Cancer Occurrence As the Upcoming Complications of Covid-19, Frontiers in Molecular Biosciences (2022)
24. Clinical Characteristics of Covid-19-Infected Cancer Patients, Isfahan, Iran, Journal of Research in Medical Sciences (2022)
25. Gene Editing-Based Technologies for Beta-Hemoglobinopathies Treatment, Biology (2022)
26. Graphene Oxide Quantum Dot-Chitosan Nanotheranostic Platform As a Ph-Responsive Carrier for Improving Curcumin Uptake Internalization: In Vitro & in Silico Study, Biomaterials Advances (2022)
27. Mesoporous Silica@Chitosan@Gold Nanoparticles As “On/Off” Optical Biosensor and Ph-Sensitive Theranostic Platform Against Cancer, International Journal of Biological Macromolecules (2022)
28. Microrna-200C Overexpression in Cancer-Associated Fibroblasts Decreases Interleukin-2 Secretion, Clinical and Translational Discovery (2022)
29. Microrna-200C Overexpression in Cancer-Associated Fibroblasts Reduces the Invasive Properties of Breast Tumour Cells, Clinical and Translational Discovery (2022)
30. Recent Advancement in Electrode Materials and Fabrication, Microfluidic Designs, and Self-Powered Systems for Wearable Non-Invasive Electrochemical Glucose Monitoring, Applied Materials Today (2022)
31. The Importance of Snps at Mirna Binding Sites As Biomarkers of Gastric and Colorectal Cancers: A Systematic Review, Journal of Personalized Medicine (2022)
32. Three-Dimensional in Vitro Models: A Promising Tool to Scale-Up Breast Cancer Research, ACS Biomaterials Science and Engineering (2022)
33. Anti-Inflammatory Effects of Apocynin: A Narrative Review of the Evidence, All Life (2021)
34. Apolipoprotein B Gene Mutation Related to Familial Hypercholesterolemia in an Iranian Population: With or Without Hypothyroidism, Journal of Research in Medical Sciences (2021)
35. Cancer-Associated Fibroblasts Regulate the Plasticity of Breast Cancer Stemness Through the Production of Leukemia Inhibitory Factor, Life (2021)
36. Corrigendum To: “Novel and Emerging Mutations of Sars-Cov-2: Biomedical Implications” [Biomed. Pharmacother. 139 (2021) 111599] (Biomedicine & Pharmacotherapy (2021) 139, (S075333222100384x), (10.1016/J.Biopha.2021.111599)), Biomedicine and Pharmacotherapy (2021)
37. Corrigendum To: “Novel and Emerging Mutations of Sars-Cov-2: Biomedical Implications” [Biomed. Pharmacother. 139 (2021) 111599] (Biomedicine & Pharmacotherapy (2021) 139, (S075333222100384x), (10.1016/J.Biopha.2021.111599)), Biomedicine and Pharmacotherapy (2021)
38. Generation of Hbsag Dna Aptamer Using Modified Cell-Based Selex Strategy, Molecular Biology Reports (2021)
39. Gold Nano/Micro-Islands Overcome the Molecularly Imprinted Polymer Limitations to Achieve Ultrasensitive Protein Detection, ACS Sensors (2021)
40. Nanobased Platforms for Diagnosis and Treatment of Covid-19: From Benchtop to Bedside, ACS Biomaterials Science and Engineering (2021)
41. Novel and Emerging Mutations of Sars-Cov-2: Biomedical Implications, Biomedicine and Pharmacotherapy (2021)
42. Novel and Emerging Mutations of Sars-Cov-2: Biomedical Implications, Biomedicine and Pharmacotherapy (2021)
43. Organoid Technology: Current Standing and Future Perspectives, Stem Cells (2021)
44. The Molecular Basis of Covid-19 Pathogenesis, Conventional and Nanomedicine Therapy, International Journal of Molecular Sciences (2021)
45. Leukemia Inhibitory Factor: A Main Controller of Breast Cancer, Journal of Biosciences (2020)
46. Measurement of Pyruvate Dehydrogenase Enzyme in Patients With Diffuse Large B-Cell Lymphoma Relapse, Tehran University Medical Journal (2020)
47. Micrornas As the Actors in the Atherosclerosis Scenario, Journal of Physiology and Biochemistry (2020)
48. Micrornas As the Actors in the Atherosclerosis Scenario, Journal of Physiology and Biochemistry (2020)
49. Protective Effects of Doxepin Cream on Radiation Dermatitis in Breast Cancer: A Single Arm Double-Blind Randomized Clinical Trial, British Journal of Clinical Pharmacology (2020)
50. Protective Effects of Doxepin Cream on Radiation Dermatitis in Breast Cancer: A Single Arm Double-Blind Randomized Clinical Trial, British Journal of Clinical Pharmacology (2020)
51. Targeting of Cholera Toxin a (Ctxa) Gene by Zinc Finger Nuclease: Pitfalls of Using Gene Editing Tools in Prokaryotes, Research in Pharmaceutical Sciences (2020)
52. Targeting of Cholera Toxin a (Ctxa) Gene by Zinc Finger Nuclease: Pitfalls of Using Gene Editing Tools in Prokaryotes, Research in Pharmaceutical Sciences (2020)
53. The Possible Role of Glucose-6-Phosphate Dehydrogenase Deficiency in Covid-19 Global Prevalence and Distribution, Journal of Research in Medical Sciences (2020)
54. Development of Α4 Integrin Dna Aptamer As a Potential Therapeutic Tool for Multiple Sclerosis, Journal of Cellular Biochemistry (2019)
55. Development of Α4 Integrin Dna Aptamer As a Potential Therapeutic Tool for Multiple Sclerosis, Journal of Cellular Biochemistry (2019)
56. Engineered Zinc-Finger Nuclease to Generate Site-Directed Modification in the Klf1 Gene for Fetal Hemoglobin Induction, Journal of Cellular Biochemistry (2019)
57. Engineered Zinc-Finger Nuclease to Generate Site-Directed Modification in the Klf1 Gene for Fetal Hemoglobin Induction, Journal of Cellular Biochemistry (2019)
58. Evidence for Expression of Promoterless Gfp Cassette: Is Gfp an Ideal Reporter Gene in Biotechnology Science?, Research in Pharmaceutical Sciences (2019)
59. Evidence for Expression of Promoterless Gfp Cassette: Is Gfp an Ideal Reporter Gene in Biotechnology Science?, Research in Pharmaceutical Sciences (2019)
60. Construction and Characterization of Human Embryonic Kidney-(Hek)-293T Cell Overexpressing Truncated Α4 Integrin, Research in Pharmaceutical Sciences (2018)
61. Construction and Characterization of Human Embryonic Kidney-(Hek)-293T Cell Overexpressing Truncated Α4 Integrin, Research in Pharmaceutical Sciences (2018)
62. Disruption of Sox6 Gene Using Crispr/Cas9 Technology for Gamma-Globin Reactivation: An Approach Towards Gene Therapy of Β-Thalassemia, Journal of Cellular Biochemistry (2018)
63. Genetic Study of the Braf Gene Reveals New Variants and High Frequency of the V600e Mutation Among Iranian Ameloblastoma Patients, Journal of Oral Pathology and Medicine (2018)
64. Inducing Indel Mutation in the Sox6 Gene by Zinc Finger Nuclease for Gamma Reactivation: An Approach Towards Gene Therapy of Beta Thalassemia, Journal of Cellular Biochemistry (2018)
65. Induction of Apoptosis in Toxoplasma Gondii Infected Hela Cells by Cisplatin and Sodium Azide and Isolation of Apoptotic Bodies and Potential Use for Vaccination Against Toxoplasma Gondii, Iranian Journal of Parasitology (2018)
66. A Novel Pathogenic Variant in an Iranian Ataxia Telangiectasia Family Revealed by Next-Generation Sequencing Followed by in Silico Analysis, Journal of the Neurological Sciences (2017)
67. Aptamers Against Pro- and Anti-Inflammatory Cytokines: A Review, Inflammation (2017)
68. Cancers of the Endocrine System, Cancer Genetics and Psychotherapy (2017)
69. The Silencing Effect of Mir-30A on Itga4 Gene Expression in Vitro: An Approach for Gene Therapy, Research in Pharmaceutical Sciences (2017)
70. The Silencing Effect of Mir-30A on Itga4 Gene Expression in Vitro: An Approach for Gene Therapy, Research in Pharmaceutical Sciences (2017)
71. Antiproliferative Effect of a Synthetic Aptamer Mimicking Androgen Response Elements in the Lncap Cell Line, Cancer Gene Therapy (2016)
72. Comparison of Different Methods for Erythroid Differentiation in the K562 Cell Line, Biotechnology Letters (2016)
73. Comparison of Different Methods for Erythroid Differentiation in the K562 Cell Line, Biotechnology Letters (2016)
74. Gamma Reactivation Using the Spongy Effect of Klf1-Binding Site Sequence: An Approach in Gene Therapy for Beta-Thalassemia, Iranian Journal of Basic Medical Sciences (2016)
75. Genetic Disruption of the Klf1 Gene to Overexpress the Γ-Globin Gene Using the Crispr/Cas9 System, Journal of Gene Medicine (2016)
76. Genetic Disruption of the Klf1 Gene to Overexpress the Γ-Globin Gene Using the Crispr/Cas9 System, Journal of Gene Medicine (2016)
77. Using Intron Splicing Trick for Preferential Gene Expression in Transduced Cells: An Approach for Suicide Gene Therapy, Cancer Gene Therapy (2016)
78. Using Intron Splicing Trick for Preferential Gene Expression in Transduced Cells: An Approach for Suicide Gene Therapy, Cancer Gene Therapy (2016)
79. Zinc Finger Nuclease: A New Approach to Overcome Beta-Lactam Antibiotic Resistance, Jundishapur Journal of Microbiology (2016)
80. Zinc Finger Nuclease: A New Approach to Overcome Beta-Lactam Antibiotic Resistance, Jundishapur Journal of Microbiology (2016)
81. A Lentiviral Vector Expressing Desired Gene Only in Transduced Cells: An Approach for Suicide Gene Therapy, Molecular Biotechnology (2015)
82. A Lentiviral Vector Expressing Desired Gene Only in Transduced Cells: An Approach for Suicide Gene Therapy, Molecular Biotechnology (2015)
83. Interleukin-1 Β Gene Polymorphisms in Iranian Patients With Uterine Fibroid, a Case-Control Study, Biosciences Biotechnology Research Asia (2015)
84. Staphylococcus Aureus Isolates Carrying Panton-Valentine Leucocidin Genes: Their Frequency, Antimicrobial Patterns, and Association With Infectious Disease in Shahrekord City, Southwest Iran, Jundishapur Journal of Microbiology (2015)
85. Staphylococcus Aureus Isolates Carrying Panton-Valentine Leucocidin Genes: Their Frequency, Antimicrobial Patterns, and Association With Infectious Disease in Shahrekord City, Southwest Iran, Jundishapur Journal of Microbiology (2015)