Tehran University of Medical Sciences

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Faculty Members have conducted research related to the Leishmania Major P27 Gene Knockout As a Novel Live Attenuated Vaccine Candidate: Protective Immunity and Efficacy Evaluation Against Cutaneous and Visceral Leishmaniasis in Balb/C Mice
Mohammad Reza Khorramizadeh
Mohammad Reza Khorramizadeh

Professor of Biotechnology

Endocrinology and Metabolism Research Center

Endocrinology and Metabolism Research Institute

Tehran University of Medical Sciences

All Documents
1. Differentiation of Pancreatic Beta Cells: Dual Acting of Inflammatory Factors, Current Stem Cell Research and Therapy (2024)
2. Synthesis and Molecular Docking Studies of New Aryl Imeglimin Derivatives As a Potent Antidiabetic Agent in a Diabetic Zebrafish Model, Scientific Reports (2024)
3. Adverse Effects of Polystyrene Nanoplastic and Its Binary Mixtures With Nonylphenol on Zebrafish Nervous System: From Oxidative Stress to Impaired Neurotransmitter System, Environmental Pollution (2023)
4. Assessment of Resveratrol on Diabetes of Zebrafish (Danio Rerio), Journal of Diabetes and Metabolic Disorders (2022)
5. Design and Characterization of a Recombinant Brucella Abortus Rb51 Vaccine That Elicits Enhanced T Cell-Mediated Immune Response, Vaccines (2022)
6. Design and Characterization of a Recombinant Brucella Abortus Rb51 Vaccine That Elicits Enhanced T Cell-Mediated Immune Response, Vaccines (2022)
7. Evaluation of a Novel Echinococcus Granulosus Recombinant Fusion B-Epc1 Antigen for the Diagnosis of Human Cystic Echinococcosis Using Indirect Elisa in Comparison With a Commercial Diagnostic Elisa Kit, Experimental Parasitology (2022)
8. Interactive Relationship Between Trp Metabolites and Gut Microbiota: The Impact on Human Pathology of Disease, Journal of Applied Microbiology (2022)
9. Introduction to the Potential of Ferula Ovina in Dental Implant Research Due to Estrogenic Bioactive Compounds and Adhesive Properties, PLoS ONE (2022)
10. Serum Matrix Metalloproteinases in Patients With Different Types of Cutis Laxa: A Case Series, Iranian Journal of Dermatology (2022)
11. Correction To: Concurrent Metformin and Silibinin Therapy in Diabetes: Assessments in Zebrafish (Danio Rerio) Animal Model (Journal of Diabetes & Metabolic Disorders, (2020), 19, 2, (1233-1244), 10.1007/S40200-020-00637-7), Journal of Diabetes and Metabolic Disorders (2021)
12. Gut Micobiota Alteration by Lactobacillus Rhamnosus Reduces Pro-Inflammatory Cytokines and Glucose Level in the Adult Model of Zebrafish, BMC Research Notes (2021)
13. Research Paper: The Repression of Matrix Metalloproteinases and Cytokine Secretion in Glioblastoma by Targeting K+ Channel, Basic and Clinical Neuroscience (2021)
14. Serotonin Level As a Potent Diabetes Biomarker Based on Electrochemical Sensing: A New Approach in a Zebra Fish Model, Analytical and Bioanalytical Chemistry (2021)
15. Studying the Expression Efficiencies of Human Clotting Factix Analogs, Rationally-Designed for Hyper-Glycosylation, Iranian Journal of Pharmaceutical Research (2021)
16. A Ph-Sensitive Delivery System Based on N-Succinyl Chitosan-Zno Nanoparticles for Improving Antibacterial and Anticancer Activities of Curcumin, International Journal of Biological Macromolecules (2020)
17. Animal Models for Human Disease, Animal Biotechnology: Models in Discovery and Translation (2020)
18. Beneficial Effects of Cold Atmospheric Plasma on Inflammatory Phase of Diabetic Foot Ulcers; a Randomized Clinical Trial, Journal of Diabetes and Metabolic Disorders (2020)
19. Concurrent Metformin and Silibinin Therapy in Diabetes: Assessments in Zebrafish (Danio Rerio) Animal Model, Journal of Diabetes and Metabolic Disorders (2020)
20. Design and Fabrication of Electrochemical Biosensor Based on Nano-Graphene to Detect Serotonin in Diabetic Zebra Fish, Iranian Journal of Diabetes and Metabolism (2020)
21. Determination of the Biomarker L-Tryptophan Level in Diabetic and Normal Human Serum Based on an Electrochemical Sensing Method Using Reduced Graphene Oxide/Gold Nanoparticles/18-Crown-6, Analytical and Bioanalytical Chemistry (2020)
22. Electrochemical Detection of Serotonin: A New Approach, Clinica Chimica Acta (2020)
23. Antibacterial and Antioxidant Assessment of Cellulose Acetate/Polycaprolactone Nanofibrous Mats Impregnated With Propolis, International Journal of Biological Macromolecules (2019)
24. Augmented Camp Signaling by Co-Administration of Resveratrol and Curcumin: A Cellular Biosensor Kinetic Assessment, Iranian Journal of Public Health (2019)
25. Design and Construction of a Fusion Peptide Containing B1, B2, B4, and Epc1 Epitopes for Diagnosis of Human Cystic Echinococcosis, Iranian Journal of Public Health (2019)
26. Flower-Like Curcumin-Loaded Folic Acid-Conjugated Zno-Mpa- Î’cyclodextrin Nanostructures Enhanced Anticancer Activity and Cellular Uptake of Curcumin in Breast Cancer Cells, Materials Science and Engineering C (2019)
27. Functional Deimmunization of Interferon Beta-1B by Identifying and Silencing Human T Cells Epitopes, Iranian Journal of Allergy# Asthma and Immunology (2019)
28. In Silico Studying of the Whole Protein Structure and Dynamics of Dickkopf Family Members Showed That N-Terminal Domain of Dickkopf 2 in Contrary to Other Dickkopfs Facilitates Its Interaction With Low Density Lipoprotein Receptor Related Protein 5/6, Journal of Biomolecular Structure and Dynamics (2019)
29. Inhibitory Effect of Coadministration of Silibinin and Cpg-Odn2006 on Metastatic Characteristics (Mmp-2 and Tlr-9) of Hepatocarcinoma Cell Line, Journal of Mazandaran University of Medical Sciences (2019)
30. Nanomaterial Based Electrochemical Sensing of the Biomarker Serotonin: A Comprehensive Review, Microchimica Acta (2019)
31. Optimization and Comparison of Different Methods and Factors for Efficient Transformation of Brucella Abortus Rb51strain, Advanced Biomedical Research (2019)
32. Optimization and Comparison of Different Methods and Factors for Efficient Transformation of Brucella Abortus Rb51strain, Advanced Biomedical Research (2019)
33. The Detection of Mycoplasma Spp. Dna in Synovial Fluid of Patients With Inflammatory Arthritis Using Pcr-Rflp, Infection# Epidemiology and Microbiology (2019)
34. Assessment of the Inhibitory Effects of Ficin-Hydrolyzed Gelatin Derived From Squid (Uroteuthis Duvauceli) on Breast Cancer Cell Lines and Animal Model, Iranian Journal of Allergy# Asthma and Immunology (2018)
35. Cellulose Acetate Electrospun Nanofibers for Drug Delivery Systems: Applications and Recent Advances, Carbohydrate Polymers (2018)
36. Development of New Generation of Vaccines for Brucella Abortus, Heliyon (2018)
37. Development of New Generation of Vaccines for Brucella Abortus, Heliyon (2018)
38. Effect of Passage Number and Culture Time on the Expression and Activity of Insulin-Degrading Enzyme in Caco-2 Cells, Iranian Biomedical Journal (2018)
39. Hmw1555-914, Hmw2553-916, and Hia585-705As Subunit Vaccine Candidates of Nontypeable Haemophilus Influenzae Induce Specific Antibody Responses With Bactericidal Activity in Balb/C, Jundishapur Journal of Microbiology (2018)
40. Inhibition of Insulin Degrading Enzyme and Insulin Degradation by Uv-Killed Lactobacillus Acidophilus, Medical sciences (Basel# Switzerland) (2018)
41. Investigation of Antitumor Effects of Lactobacillus Crispatus in Experimental Model of Breast Cancer in Balb/C Mice, Immunotherapy (2018)
42. Vector and Cell Line Engineering Technologies Toward Recombinant Protein Expression in Mammalian Cell Lines, Applied Biochemistry and Biotechnology (2018)
43. A Study of the Effect of Aspirin and Atorvastatin on the Phenotypes of Liver Cancer Cells in a Cell Culture Model, Journal of Babol University of Medical Sciences (2017)
44. Cell Membrane and Intracellular Expression of Toll-Like Receptor 9 (Tlr9) in Colorectal Cancer and Breast Cancer Cell-Lines, Cancer Biomarkers (2017)
45. Comparative Assessment on the Expression Level of Recombinant Human Follicle-Stimulating Hormone (Fsh) in Serum-Containing Versus Protein-Free Culture Media, Molecular Biotechnology (2017)
46. Enhanced Cardiac Differentiation of Human Cardiovascular Disease Patient-Specific Induced Pluripotent Stem Cells by Applying Unidirectional Electrical Pulses Using Aligned Electroactive Nanofibrous Scaffolds, ACS Applied Materials and Interfaces (2017)
47. Expression of Recombinant Parvalbumin From Wolf-Herring Fish and Determination of Its Ige-Binding Capability, Food and Agricultural Immunology (2017)
48. Functionalization of Zno Nanoparticles by 3-Mercaptopropionic Acid for Aqueous Curcumin Delivery: Synthesis, Characterization, and Anticancer Assessment, Materials Science and Engineering C (2017)
49. Identification of Methionine Oxidation in Human Recombinant Erythropoietin by Mass Spectrometry: Comparative Isoform Distribution and Biological Activity Analysis, Preparative Biochemistry and Biotechnology (2017)
50. Molecular Design, Expression and Evaluation of Pasylated Human Recombinant Erythropoietin With Enhanced Functional Properties, Protein Journal (2017)
51. Potential Efficacy of Lactobacillus Casei Ibrc_M10711 on Expression and Activity of Insulin Degrading Enzyme But Not Insulin Degradation, In Vitro Cellular and Developmental Biology - Animal (2017)
52. Targeted Intracellular Heat Transfer in Cancer Therapy: Assessment of Asparagine-Laminated Gold Nanoparticles in Cell Model of T Cell Leukemia, Iranian Journal of Public Health (2017)
53. Biotin/Folate-Decorated Human Serum Albumin Nanoparticles of Docetaxel: Comparison of Chemically Conjugated Nanostructures and Physically Loaded Nanoparticles for Targeting of Breast Cancer, Chemical Biology and Drug Design (2016)
54. Cloning and Expression of Human Bone Morphogenetic Protein-2 Gene in Leishmania Tarentolae, Biocatalysis and Agricultural Biotechnology (2016)
55. Coagulase Gene Polymorphism of Staphylococcus Aureus Isolates: A Study on Dairy Food Products and Other Foods in Tehran, Iran, Food Science and Human Wellness (2016)
56. Collagen Extracted From Persian Gulf Squid Exhibits Anti-Cytotoxic Properties on Apple Pectic Treated Cells: Assessment in an in Vitro Bioassay Model, Iranian Journal of Public Health (2016)
57. Dual Anti-Metastatic and Anti-Proliferative Activity Assessment of Two Probiotics on Hela and Ht-29 Cell Lines, Cell Journal (2016)
58. Identification and Characterization of Main Allergic Proteins in Cooked Wolf Herring Fish, Iranian Journal of Allergy# Asthma and Immunology (2016)
59. In Silico Designing of Hyper-Glycosylated Analogs for the Human Coagulation Factor Ix, Journal of Molecular Graphics and Modelling (2016)
60. Lactobacillus Crispatus Strain Sj-3C-Us Induces Human Dendritic Cells (Dcs) Maturation and Confers an Anti-Inflammatory Phenotype to Dcs, APMIS (2016)
61. Bypassing the Need for Pre-Sensitization of Cancer Cells for Anticancer Trail Therapy With Secretion of Novel Cell Penetrable Form of Smac From Ha-Mscs As Cellular Delivery Vehicle, Tumor Biology (2015)
62. Bypassing the Need for Pre-Sensitization of Cancer Cells for Anticancer Trail Therapy With Secretion of Novel Cell Penetrable Form of Smac From Ha-Mscs As Cellular Delivery Vehicle, Tumor Biology (2015)
63. Comparative Proteomic Profiling of Leishmania Tropica: Investigation of a Case Infected With Simultaneous Cutaneous and Viscerotropic Leishmaniasis by 2-Dimentional Electrophoresis and Mass Spectrometry, Iranian Journal of Parasitology (2015)
64. Comparison of the Proteome Profiling of Iranian Isolates of Leishmania Tropica, L. Major and L. Infantum by Two-Dimensional Electrophoresis (2-De) and Mass-Spectrometry, Iranian Journal of Parasitology (2015)
65. Erratum to Evaluation of Optimal Concentration and Exposure Duration of Valproic Acid Alone or in Combination With Viraductin to Augment Adenovirus Transduction in Human Adipose Stem Cells [Cytotherapy, 16, (2014), 612-618], Cytotherapy (2015)
66. Growth Inhibition of Mda-Mb-231 Cell Line by Peptides Designed Based on Upa, Acta medica Iranica (2015)
67. Growth Inhibition of Mda-Mb-231 Cell Line by Peptides Designed Based on Upa, Acta Medica Iranica (2015)
68. Pectic-Oligoshaccharides From Apples Induce Apoptosis and Cell Cycle Arrest in Mda-Mb-231 Cells, a Model of Human Breast Cancer, Asian Pacific Journal of Cancer Prevention (2015)
69. Silencing the Wild-Type and Mutant K-Ras Increases the Resistance to 5-Flurouracil in Hct-116 As a Colorectal Cancer Cell Line, Anti-cancer drugs (2015)
70. Upar Peptide Antagonist Alters Regulation of Map Kinases and Bcl-2 Family Members in Favor of Apoptosis in Mda-Mb-231 Cell Line, Research in Pharmaceutical Sciences (2015)