Tehran University of Medical Sciences

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Faculty Members have conducted research related to the Cloning and Expression of Major Surface Antigen 1 Gene of Toxoplasma Gondii Rh Strain Using the Expression Vector Pvax1 in Chinese Hamster Ovary Cells
Hossein Keshavarz Valian
Hossein Keshavarz Valian

Professor of Medical Parasitology

Department Medical Parasitology and Mycology

School of Public Health

Center for Research of Endemic Parasites of Iran

Tehran University of Medical Sciences

All Documents
1. Formulation, in Vitro Evaluation and Therapeutic Effect of Chitosan Coated Pluronic F127 Micelles Containing Miltefosine for the Treatment of Visceral Leishmaniasis in Domestic Dogs Naturally Infected by Leishmania Infantum, Research in Veterinary Science (2025)
2. Formulation and Evaluation of Atovaquone-Loaded Macrophage-Derived Exosomes Against Toxoplasma Gondii: In Vitro and in Vivo Assessment, Microbiology Spectrum (2024)
3. Associations Between Toxoplasma Gondii Infection and Multiple Sclerosis: A Case-Control Seroprevalence Study, Iranian Journal of Parasitology (2023)
4. Electrochemical Immunosensor Based on Carbon Nanofibers and Gold Nanoparticles for Detecting Anti-Toxoplasma Gondii Igg Antibodies, Microchimica Acta (2023)
5. Field Efficacy of Topical Nano-Liposomal Amphotericin B (Sina Ampholeish®) Alone or in Combination With Glucantime® and Cryotherapy on Human Cutaneous Leishmaniasis, Iranian Journal of Parasitology (2023)
6. Genetic Diversity of Merozoite Surface Protein-5 (Msp-5) of Plasmodium Vivax Isolates From Malaria Patients in Iran, BMC Infectious Diseases (2023)
7. Molecular Identification of Cutaneous Leishmaniasis Species in the Northcentral Iranian Province of Alborz: Is There a New Focus on Cutaneous Leishmaniasis in the Province?, Iranian Journal of Parasitology (2023)
8. Nanoemulsion of Spiramycin Against Tachyzoites of Toxoplasma Gondii, Rh Strain: Preparation, Toxicology, and Efficacy Studies, Iranian Journal of Public Health (2023)
9. The Therapeutic Efficacy of Zinc Oxide Nanoparticles on Acute Toxoplasmosis in Balb/C Mice, Iranian Journal of Parasitology (2023)
10. Visceral Leishmaniasis in Iran: An Update on Epidemiological Features From 2013 to 2022, Iranian Journal of Parasitology (2023)
11. Key Plasma Micrornas Variations in Patients With Plasmodium Vivax Malaria in Iran, Heliyon (2022)
12. Toxoplasma Gondii Infection in Immunocompromised Patients in Iran (2013-2022): A Systematic Review and Meta-Analysis, Iranian Journal of Parasitology (2022)
13. Utility of Blood As the Clinical Specimen for the Diagnosis of Ocular Toxoplasmosis Using Uracil Dna Glycosylase-Supplemented Loop-Mediated Isothermal Amplification and Real-Time Polymerase Chain Reaction Assays Based on Rep-529 Sequence and B1 Gene, BMC Infectious Diseases (2022)
14. Utility of Blood As the Clinical Specimen for the Diagnosis of Ocular Toxoplasmosis Using Uracil Dna Glycosylase-Supplemented Loop-Mediated Isothermal Amplification and Real-Time Polymerase Chain Reaction Assays Based on Rep-529 Sequence and B1 Gene, BMC Infectious Diseases (2022)
15. Assessment of an In-House Enzyme-Linked Immunosorbent Assay and Igg Avidity Test Based on Sag1 and Gra7 Proteins for Discriminating Between Acute and Chronic Toxoplasmosis in Humans, Journal of Clinical Microbiology (2021)
16. Chronic Toxoplasma Gondii Infection Potentiates Parkinson’S Disease Course in Mice Model, Iranian Journal of Parasitology (2021)
17. Combination of Topical Liposomal Amphotericin B and Glucantime in Comparison With Glucantime Alone for the Treatment of Anthroponotic Cutaneous Leishmaniasis (Acl) Caused by Leishmania Tropica: Study Protocol for a Randomized, Controlled Trial, Iranian Journal of Microbiology (2021)
18. Intestinal Parasites Among Food Handlers in Iran: A Systematic Review and Meta-Analysis, Food Microbiology (2021)
19. Prediction of Malaria Cases in the Southeastern Iran Using Climatic Variables: An 18-Year Sarima Time Series Analysis, Asian Pacific Journal of Tropical Medicine (2021)
20. Seroepidemiological Study of Toxoplasmosis in Women Referred to a Pre-Marriage Counseling Center in Alborz Province, Iran, BMC Research Notes (2021)
21. Spatial Distribution of Common Pathogenic Human Intestinal Protozoa in Iran: A Systematic Review, Iranian Journal of Public Health (2021)
22. The Drug Resistance of Plasmodium Falciparum and P. Vivax in Iran: A Review Article, Iranian Journal of Parasitology (2021)
23. The Emergence of Co-Infection of Visceral Leishmaniasis in an Iranian Child With Chronic Granulomatous Disease: A Case Report, Iranian Journal of Parasitology (2021)
24. Clinical and Epidemiologic Features of Visceral Leishmaniasis in Children: A 6-Year Study From an Iranian Referral Hospital, Infectious Disorders - Drug Targets (2020)
25. Comparison of the Re-529 Sequence and B1 Gene for Toxoplasma Gondii Detection in Blood Samples of the At-Risk Seropositive Cases Using Uracil Dna Glycosylase Supplemented Loop-Mediated Isothermal Amplification (Udg-Lamp) Assay, Microbial Pathogenesis (2020)
26. Comparison of the Re-529 Sequence and B1 Gene for Toxoplasma Gondii Detection in Blood Samples of the At-Risk Seropositive Cases Using Uracil Dna Glycosylase Supplemented Loop-Mediated Isothermal Amplification (Udg-Lamp) Assay, Microbial Pathogenesis (2020)
27. Development of High Resolution Melting Analysis As a Diagnostic Tool for Molecular Detection of Toxoplasma Infection in Pregnant Women and Hiv Positive Cases, Iranian Journal of Public Health (2020)
28. Molecular and Seroepidemiological Survey of Visceral Leishmaniasis in Owned Dogs (Canis Familiaris) in New Foci of Rural Areas of Alborz Province, Central Part of Iran: A Cross-Sectional Study in 2017, Journal of Arthropod-Borne Diseases (2020)
29. Role of Toxoplasma Gondii Igg Avidity Testing in Discriminating Between Acute and Chronic Toxoplasmosis in Pregnancy, Journal of Clinical Microbiology (2020)
30. Sarcocystis Infection in Beef and Industrial Raw Beef Burgers From Butcheries and Retail Stores: A Molecular Microscopic Study, Heliyon (2020)
31. The Diagnostic Accuracy of Direct Agglutination Test for Serodiagnosis of Human Visceral Leishmaniasis: A Systematic Review With Meta-Analysis, BMC Infectious Diseases (2020)
32. The Parasitic Contamination of Edible Raw Vegetables in Karaj, Iran in 2017, Iranian Journal of Public Health (2020)
33. Assessment of the Immunogenicity and Protective Efficiency of a Novel Dual-Promoter Dna Vaccine, Harboring Sag1 and Gra7 Genes, From Rh Strain of Toxoplasma Gondii in Balb/C Mice, Infection and Drug Resistance (2019)
34. Asymptomatic Malaria Infections Among Immigrants in Malaria-Elimination Programmed Areas of South Eastern Iran May Threaten Malaria Eradication, Travel Medicine and Infectious Disease (2019)
35. Asymptomatic Malaria Infections Among Immigrants in Malaria-Elimination Programmed Areas of South Eastern Iran May Threaten Malaria Eradication, Travel Medicine and Infectious Disease (2019)
36. Blood Donor Deferrals for Malaria in Iran: A Five-Year Retrospective Study, Iranian Journal of Parasitology (2019)
37. Detection of Toxoplasma Gondii in Cord Blood Samples From Neonates in Tehran, Iran, Iranian Journal of Public Health (2019)
38. Development, Optimization, and Validation of an In-House Dot-Elisa Rapid Test Based on Sag1 and Gra7 Proteins for Serological Detection of Toxoplasma Gondii Infections, Infection and Drug Resistance (2019)
39. Effects of Some Natural Products From Fungal and Herbal Sources on Giardia Lamblia in Vivo, Parasitology (2019)
40. Epidemiology of Echinococcosis in Iran: A Systematic Review and Meta-Analysis, BMC Infectious Diseases (2019)
41. Evaluation of Re and B1 Genes As Targets for Detection of Toxoplasma Gondii by Nested Pcr in Blood Samples of Patients With Ocular Toxoplasmosis, Acta Parasitologica (2019)
42. Leishmania Major P27 Gene Knockout As a Novel Live Attenuated Vaccine Candidate: Protective Immunity and Efficacy Evaluation Against Cutaneous and Visceral Leishmaniasis in Balb/C Mice, Vaccine (2019)
43. Nanosilver Colloid Inhibits Toxoplasma Gondii Tachyzoites and Bradyzoites in Vitro, Iranian Journal of Parasitology (2019)
44. The Relation of Serum Prolactin Levels and Toxoplasma Infection in Humans, International Journal of General Medicine (2019)
45. Vitamin D Deficiency and Toxoplasma Infection, Iranian Journal of Public Health (2019)
46. Anti-Toxoplasma Activity of Various Molecular Weights and Concentrations of Chitosan Nanoparticles on Tachyzoites of Rh Strain, International Journal of Nanomedicine (2018)
47. Comparison of P27 Gene Expression of Promastigote and Amastigote Forms of Leishmania Major (Mrho/Ir/75/Er) by Real-Time Rt-Pcr, Iranian Journal of Parasitology (2018)
48. Curcumin Nanoemulsion As a Novel Chemical for the Treatment of Acute and Chronic Toxoplasmosis in Mice, International Journal of Nanomedicine (2018)
49. Design of a Dual-Promoter Expression Vector Harboring Sag1 and Gra7 Genes From Toxoplasma Gondii (Rh Strain), Tropical Biomedicine (2018)
50. Detection of Toxoplasma Gondi in Acute and Chronic Phases of Infection in Immunocompromised Patients and Pregnant Women With Real-Time Pcr Assay Using Taqman Fluorescent Probe, Iranian Journal of Parasitology (2018)
51. Detection of Toxoplasma Gondi in Acute and Chronic Phases of Infection in Immunocompromised Patients and Pregnant Women With Real-Time Pcr Assay Using Taqman Fluorescent Probe, Iranian Journal of Parasitology (2018)
52. Detection of Toxoplasma-Specific Immunoglobulin G in Human Sera: Performance Comparison of in House Dot-Elisa With Eclia and Elisa, European Journal of Clinical Microbiology and Infectious Diseases (2018)
53. Development of a New Live Attenuated Leishmania Major P27 Gene Knockout: Safety and Immunogenicity Evaluation in Balb/C Mice, Cellular Immunology (2018)
54. Epidemiological Study of Cutaneous Leishmaniasis in Some Iraqi Provinces, Journal of Men's Health (2018)
55. Genetic Diversity in C-Terminal of Sera5 Gene in the Blood Stage of Human Isolates of Plasmodium Vivax in Sistan and Baluchistan, Iran, Iranian Journal of Parasitology (2018)
56. In Vitro Culture of Toxoplasma Gondii in Hela, Vero, Rbk and A549 Cell Lines, Infezioni in Medicina (2018)
57. Malaria Vaccine Development: The Need for Novel Approaches: A Review Article, Iranian Journal of Parasitology (2018)
58. Nanoemulsion of Atovaquone As a Promising Approach for Treatment of Acute and Chronic Toxoplasmosis, European Journal of Pharmaceutical Sciences (2018)
59. Safety Evaluation of Nano-Liposomal Formulation of Amphotericin B (Sina Ampholeish) in Animal Model As a Candidate for Treatment of Cutaneous Leishmaniasis, Journal of Arthropod-Borne Diseases (2018)
60. Serologic Tests of Igg and Igm Antibodies and Igg Avidity for Diagnosis of Ocular Toxoplasmosis, Korean Journal of Parasitology (2018)
61. The Association of Latent Toxoplasmosis and Level of Serum Testosterone in Humans, BMC Research Notes (2018)
62. The Relation of Secondary Sex Ratio and Miscarriage History With Toxoplasma Gondii Infection, BMC Infectious Diseases (2018)
63. Asymptomatic Malaria and Its Challenges in the Malaria Elimination Program in Iran: A Systematic Review, Journal of Arthropod-Borne Diseases (2017)
64. Comparison of the Toxoplasma Gondii Mice and Cell Culture Derived Antigens in Elisa Assay, Tropical Biomedicine (2017)
65. Early Detection of Toxoplasma Gondii Infection by Using a Interferon Gamma Release Assay: A Review, Experimental Parasitology (2017)
66. Efficacy of Phase 3 Trial of Rts, S/As01 Malaria Vaccine: The Need for an Alternative Development Plan, Human Vaccines and Immunotherapeutics (2017)
67. Evaluation of Toxoplasma Gondii Soluble, Whole and Excretory/Secretary Antigens for Diagnosis of Toxoplasmosis by Elisa Test, Journal of Parasitic Diseases (2017)
68. Pcr-Rflp Analysis of Plasmodium Vivax Reticulocyte Binding Protein2c Gene in Field Isolates of Iran, Tropical Biomedicine (2017)
69. Relapse of a Plasmodium Vivax Infection in an Iranian Patient: A Case Report, Jundishapur Journal of Natural Pharmaceutical Products (2017)
70. Subtype Analysis of Giardia Duodenalis Isolates From Municipal and Domestic Raw Wastewaters in Iran, Environmental Science and Pollution Research (2017)
71. Visceral Leishmaniasis in Southeastern Iran: A Narrative Review, Iranian Journal of Parasitology (2017)
72. Acetylcholinesterase Inhibitor Improves Learning and Memory Impairment Induced by Toxoplasma Gondii Infection, Iranian Journal of Parasitology (2016)
73. Cyst Formation From Virulent Rh Strain of Toxoplasma Gondii Tachyzoite: In Vitro Cultivation, Iranian Journal of Parasitology (2016)
74. Microscopic and Molecular Detection of Cryptosporidium Andersoni and Cryptosporidium Xiaoi in Wastewater Samples of Tehran Province, Iran, Iranian Journal of Parasitology (2016)
75. Molecular Typing of Eimeria Ahsata and E. Crandallis Isolated From Slaughterhouse Wastewater, Jundishapur Journal of Microbiology (2016)
76. Seroprevalence of Toxoplasma Gondii Infection in Domestic Dogs in an Area From Northwest of Iran: A Cross-Sectional Study Using Immunodominant Surface Antigen 1 (Sag1), Journal of Parasitic Diseases (2016)
77. Simplified Pan-Species Real-Time Pcr-Based Detection of Plasmodium Spp. in Blood Smear, Iranian Journal of Parasitology (2016)
78. T Helper 1 (Th1), Th2, and Th17 Responses to Leishmania Major Lipophosphoglycan 3, Immunological Investigations (2016)
79. Toxoplasma Gondii Infection Potentiates Cognitive Impairments of Alzheimer's Disease in the Balb/C Mice, Journal of Parasitology (2016)
80. Toxoplasma Gondii Infection Promotes Neuroinflammation Through Cytokine Networks and Induced Hyperalgesia in Balb/C Mice, Inflammation (2016)
81. Transfusion-Transmitted Malaria in Iran: A Narrative Review Article, Iranian Journal of Parasitology (2016)
82. A Model for Evaluation of Faculty Members’ Activities Based on Meta-Evaluation of a 5-Year Experience in Medical School, Journal of Research in Medical Sciences (2015)
83. Anti-Toxoplasma Activity of 2-(Naphthalene-2-Γlthiol)-1H Indole, Iranian Journal of Parasitology (2015)
84. Detection of Mixed-Species Infections of Plasmodium Falciparum and Plasmodium Vivax by Nested Pcr and Rapid Diagnostic Tests in Southeastern Iran, American Journal of Tropical Medicine and Hygiene (2015)
85. Detection of Parasitic Particles in Domestic and Urban Wastewaters and Assessment of Removal Efficiency of Treatment Plants in Tehran, Iran, Journal of Environmental Health Science and Engineering (2015)
86. Double-Blind Randomized Efficacy Field Trial of Alum Precipitated Autoclaved Leishmania Major (Alum-Alm) Vaccine Mixed With Bcg Plus Imiquimod Vs. Placebo Control Group, Iranian Journal of Parasitology (2015)
87. Evaluation of Cryptosporidium Oocyst and Giardia Cyst Removal Efficiency From Urban and Slaughterhouse Wastewater Treatment Plants and Assessment of Cyst Viability in Wastewater Effluent Samples From Tehran, Iran, Journal of Water Reuse and Desalination (2015)
88. Seroepidemiological Study of Toxoplasmosis in Women Referred to Arak Marriage Consulting Center During 2012-2013, Iranian Journal of Public Health (2015)
89. The Possible Association Between Toxoplasma Gondii Infection and Risk of Anxiety and Cognitive Disorders in Balb/C Mice, Pathogens and Global Health (2015)
90. Toxoplasma Gondii: Sexual Transmission in Mice, Journal of Parasitic Diseases (2015)
91. Visceral Leishmaniasis in Rural Areas of Alborz Province of Iran and Implication to Health Policy, Korean Journal of Parasitology (2015)