Tehran University of Medical Sciences

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Faculty Members have conducted research related to the Molecular Characterization and Phylogenetic Analysis of Theileria Spp. and Babesia Spp. Isolated From Various Ticks in Southeastern and Northwestern Regions of Iran
Somayeh Mojtabavi
Somayeh Mojtabavi

Assistant Professor of Pharmaceuticals, Cosmetics and Toiletries Control

Department Food and Drug Control

School of Pharmacy

Tehran University of Medical Sciences

All Documents
1. 1-Phenyl-Β-Carboline-3-Carboxamide-1,2,3-Triazole-N-Phenylacetamide Hybrids As New Α-Glucosidase Inhibitors, Scientific Reports (2025)
2. Design, Synthesis, and Evaluation of Triazolo[1,5-A]Pyridines As Novel and Potent Α‑Glucosidase Inhibitors, Scientific Reports (2025)
3. Design, Synthesis, and Investigation of Novel 5-Arylpyrazole-Glucose Hybrids As Α-Glucosidase Inhibitors, Scientific Reports (2025)
4. Green Valorization of Garlic Peel Waste Using Halophilic Laccase for Efficient Biomass Delignification and Biorefinery Applications, Scientific Reports (2025)
5. Hybrid-Based Design and Biological Evaluation of Quinoline-Benzoylhydrazine Based Derivatives As Α-Glucosidase Inhibitors, Medicinal Chemistry Research (2025)
6. In the Pursuit of an Efficient Delignification From Pumpkin Seed Shells by the Polyextremophilic and Laccase-Producing Bacterial Isolate Halomonas Elongata, Biomass Conversion and Biorefinery (2025)
7. Innovative Dual-Contrast Nanocoating for Central Venous Catheters: Prolonged Infection Resistance and Enhanced Imaging, Journal of Materials Chemistry B (2025)
8. Quinoline-Piperazine Derivatives As Potential Α-Glucosidase Inhibitors: Synthesis, Biological Evaluation, and in Silico Studies, Journal of Molecular Structure (2025)
9. Substituted Piperazine Conjugated to Quinoline-Thiosemicarbazide As Potent Α-Glucosidase Inhibitors to Target Hyperglycemia, Scientific Reports (2025)
10. A New Route to the Synthesis of 2-Hydrazolyl-4-Thiazolidinone Hybrids, Evaluation of Α-Glucosidase Inhibitory Activity and Molecular Modeling Insights, Heliyon (2024)
11. Alpha-Glucosidase Inhibitory and Hypoglycemic Effects of Imidazole-Bearing Thioquinoline Derivatives With Different Substituents: In Silico, in Vitro, and in Vivo Evaluations, Bioorganic Chemistry (2024)
12. Aryl-Quinoline-4-Carbonyl Hydrazone Bearing Different 2-Methoxyphenoxyacetamides As Potent Α-Glucosidase Inhibitors; Molecular Dynamics, Kinetic and Structure–Activity Relationship Studies, Scientific Reports (2024)
13. Design of New Α-Glucosidase Inhibitors Based on the Bis-4-Hydroxycoumarin Skeleton: Synthesis, Evaluation, and in Silico Studies, Scientific Reports (2024)
14. Design, Synthesis Docking and Molecular Dynamics Studies of 2-Amino-4-Phenylthiazole-Indole Hybrids As Α-Glucosidase Inhibitors, Journal of Molecular Structure (2024)
15. Design, Synthesis, and Evaluation of Novel Substituted Imidazo[1,2-C]Quinazoline Derivatives As Potential Α-Glucosidase Inhibitors With Bioactivity and Molecular Docking Insights, Scientific Reports (2024)
16. Design, Synthesis, in Vitro, and in Silico Anti-Α-Glucosidase Assays of N-Phenylacetamide-1,2,3-Triazole-Indole-2-Carboxamide Derivatives As New Anti-Diabetic Agents, Scientific Reports (2024)
17. Design, Synthesis, Α-Glucosidase Inhibition and Hypoglycemic Activity of 3-Aceto(Benzo)Hydrazide-1,2,4-Triazines As Potential Anti-Diabetic Agents, European Journal of Medicinal Chemistry Reports (2024)
18. Enzymatic Dual-Faced Janus Structures Based on the Hierarchical Organic-Inorganic Hybrid Matrix for an Effective Bioremoval and Detoxification of Reactive Blue-19, International Journal of Biological Macromolecules (2024)
19. Evaluation of Novel 2-(Quinoline-2-Ylthio)Acetamide Derivatives Linked to Diphenyl-Imidazole As Α-Glucosidase Inhibitors: Insights From in Silico, in Vitro, and in Vivo Studies on Their Anti-Diabetic Properties, European Journal of Medicinal Chemistry (2024)
20. Exploring the Nutritional Benefits of Acorns: Phytochemical Profiles and Biological Activity, Annals of the University Dunarea de Jos of Galati, Fascicle VI: Food Technology (2024)
21. Hierarchically-Structured Laccase@Ba3(Po4)2 Hybrid Nanoflowers Coating on the Urinary Foley Catheter With High Durability, Biocompatibility, Anti-Adhesion Activity, and Contrasting Behavior, Materials Chemistry and Physics (2024)
22. In-Silico and In-Vitro Targeting of Organic Dye Pollutants From Synthetic and Real Wastewater by the Hierarchically Self-Assembled Laccase@Bismuth Phosphate Hybrid Nanorods, Journal of Environmental Chemical Engineering (2024)
23. New Phenylthiosemicarbazide-Phenoxy-1,2,3-Triazole-N-Phenylacetamides As Dual Inhibitors Against Α-Glucosidase and Ptp-1B for the Treatment of Type 2 Diabetes, Archiv der Pharmazie (2024)
24. Quinoline-Thiosemicarbazone-1,2,3-Triazole-Acetamide Derivatives As New Potent Α-Glucosidase Inhibitors, Scientific Reports (2024)
25. Rational Design of New Quinoline-Benzimidazole Scaffold Bearing Piperazine Acetamide Derivatives As Antidiabetic Agents, Bioorganic Chemistry (2024)
26. Salvia Mirzayanii and Salvia Hypoleuca Essential Oils: Chemical Composition, Alpha-Glucosidase Inhibitory, and Synergistic Effects of Selected Components, Jundishapur Journal of Natural Pharmaceutical Products (2024)
27. Synthesis, in Vitro Potency of Inhibition, Enzyme Kinetics and in Silico Studies of Quinoline-Based Α-Glucosidase Inhibitors, Scientific Reports (2024)
28. Synthesis, Α-Glucosidase Inhibitory Activity, and Molecular Dynamic Simulation of 6-Chloro-2-Methoxyacridine Linked to Triazole Derivatives, Scientific Reports (2024)
29. Α-Glucosidase Inhibition Assay of Galbanic Acid and It Amide Derivatives: New Excellent Semi-Synthetic Α-Glucosidase Inhibitors, Bioorganic Chemistry (2024)
30. Arylureidoaurones: Synthesis, in Vitro Α-Glucosidase, and Α-Amylase Inhibition Activity, Bioorganic Chemistry (2023)
31. Biodegradation of Acid Orange-7 Dye by Immobilized Laccase on Functionalized Zsm-5 Zeolites: Investigation of the Role of Functionalization and Sio2/Al2o3 Ratio of Zeolite on the Catalytic Performance, Journal of Molecular Structure (2023)
32. Bioremoval and Biodetoxification of Ciprofloxacin From Hospital Wastewater Effluent by the Efficient and Recyclable Laccase@Hercynite Magnetic Nanoparticles, Journal of Environmental Chemical Engineering (2023)
33. Carboxylesterases, Encyclopedia of Toxicology# Fourth Edition: Volume 1-9 (2023)
34. Chemical Composition, Cholinesterase, and Α-Glucosidase Inhibitory Activity of the Essential Oils of Some Iranian Native Salvia Species, BMC Complementary Medicine and Therapies (2023)
35. Design, Synthesis, in Vitro Anti-Α-Glucosidase Evaluations, and Computational Studies of New Phthalimide-Phenoxy-1,2,3-Triazole-N-Phenyl (Or Benzyl) Acetamides As Potential Anti-Diabetic Agents, Scientific Reports (2023)
36. Design, Synthesis, in Vitro, and in Silico Evaluations of Benzo[D]Imidazole-Amide-1,2,3-Triazole-N-Arylacetamide Hybrids As New Antidiabetic Agents Targeting Α-Glucosidase, Scientific Reports (2023)
37. Development of Coumarin Tagged 1,2,3-Triazole Derivatives Targeting Α-Glucosidase Inhibition: Synthetic Modification, Biological Evaluation, Kinetic and in Silico Studies, Journal of Molecular Structure (2023)
38. Discovery of Phthalimide-1,2,3-Triazole-N-Phenylacetamide Hybrids As Potent Α-Glucosidase Inhibitors: Design, Synthesis, Admet Prediction, and in Vitro and in Silico Enzymatic Evaluations, ChemistrySelect (2023)
39. Efficient Biocatalytic Removal and Algal Detoxification of Direct Blue-15 by the Hierarchically Structured, High-Performance, and Recyclable Laccase@Yttrium Phosphate Hybrid Nanostructures, Environmental Science and Pollution Research (2023)
40. Imidazo[1,2-C]Quinazolines As a Novel and Potent Scaffold of Α-Glucosidase Inhibitors: Design, Synthesis, Biological Evaluations, and in Silico Studies, Scientific Reports (2023)
41. Indole-Carbohydrazide Linked Phenoxy-1,2,3-Triazole-N-Phenylacetamide Derivatives As Potent Α-Glucosidase Inhibitors: Design, Synthesis, in Vitro Α-Glucosidase Inhibition, and Computational Studies, BMC Chemistry (2023)
42. Novel Indolotacrine Hybrids As Acetylcholinesterase Inhibitors: Design, Synthesis, Biological Evaluation, and Molecular Docking Studies, Journal of the Iranian Chemical Society (2023)
43. Novel N′-Substituted Benzylidene Benzohydrazides Linked to 1,2,3-Triazoles: Potent Α-Glucosidase Inhibitors, Scientific Reports (2023)
44. Novel Pyrano[3,2-C]Quinoline-1,2,3-Triazole Hybrids As Potential Anti-Diabetic Agents: In Vitro Α-Glucosidase Inhibition, Kinetic, and Molecular Dynamics Simulation, ACS Omega (2023)
45. Quinazolinone-1,2,3-Triazole-Acetamide Conjugates As Potent Α-Glucosidase Inhibitors: Synthesis, Enzyme Inhibition, Kinetic Analysis, and Molecular Docking Study, RSC Medicinal Chemistry (2023)
46. Surface Functionalization of Endotracheal Tubes Coated With Laccase-Gadolinium Phosphate Hybrid Nanoparticles for Antibiofilm Activity and Contrasting Properties, Biomaterials Science (2023)
47. Synthesis and Characterization of Quercetin@Ca3(Po4)2 Hybrid Nanofibers With Antibiofilm Properties and Antioxidant Activity for the Deep-Frying Procedure of Sunflower Oil, Food and Bioprocess Technology (2023)
48. Synthesis and Structure–Activity Relationship Studies of Benzimidazole-Thioquinoline Derivatives As Α-Glucosidase Inhibitors, Scientific Reports (2023)
49. Synthesis, Admt Prediction, and in Vitro and in Silico Α-Glucosidase Inhibition Evaluations of New Quinoline-Quinazolinone-Thioacetamides, RSC Advances (2023)
50. Synthesis, in Vitro Inhibitor Screening, Structure–Activity Relationship, and Molecular Dynamic Simulation Studies of Novel Thioquinoline Derivatives As Potent Α-Glucosidase Inhibitors, Scientific Reports (2023)
51. Synthesis, in Vitro Α-Glucosidase Inhibitory Activities, and Molecular Dynamic Simulations of Novel 4-Hydroxyquinolinone-Hydrazones As Potential Antidiabetic Agents, Scientific Reports (2023)
52. Synthesis, in Vitro Α-Glucosidase Inhibitory Activity and Molecular Dynamics Simulation of Some New Coumarin-Fused 4H-Pyran Derivatives As Potential Anti-Diabetic Agents, Journal of Molecular Structure (2023)
53. Thiram: Cytotoxicity Mechanism and Applications, Encyclopedia of Toxicology# Fourth Edition: Volume 1-9 (2023)
54. Α-Glucosidase Inhibitors From the Aerial Part of Thymus Fedtschenkoi: Isolation, Kinetic and Molecular Docking Study, Chemical Papers (2023)
55. A Survey on the Stabilizing Effect of Osmolytes on the Ultrasound-Irradiated Lipase for Efficient Enzymatic Hydrolysis of Coconut Oil, Colloids and Surfaces B: Biointerfaces (2022)
56. Chemical Composition and Biological Effects of Pistacia Atlantica Desf. Oleoresin Essential Oil, Research Journal of Pharmacognosy (2022)
57. Cyanoacetohydrazide Linked to 1,2,3-Triazole Derivatives: A New Class of Α-Glucosidase Inhibitors, Scientific Reports (2022)
58. Design and Synthesis of Phenoxymethybenzoimidazole Incorporating Different Aryl Thiazole-Triazole Acetamide Derivatives As Α-Glycosidase Inhibitors, Molecular Diversity (2022)
59. Design, Synthesis, and in Silico Studies of Benzimidazole Bearing Phenoxyacetamide Derivatives As Α-Glucosidase and Α-Amylase Inhibitors, Journal of Molecular Structure (2022)
60. Design, Synthesis, and in Silico Studies of Quinoline-Based-Benzo[D]Imidazole Bearing Different Acetamide Derivatives As Potent Α-Glucosidase Inhibitors, Scientific Reports (2022)
61. Design, Synthesis, and Molecular Docking Studies of Diphenylquinoxaline-6-Carbohydrazide Hybrids As Potent Α-Glucosidase Inhibitors, BMC Chemistry (2022)
62. Design, Synthesis, in Vitro Α-Glucosidase Inhibition, Docking, and Molecular Dynamics of New Phthalimide-Benzenesulfonamide Hybrids for Targeting Type 2 Diabetes, Scientific Reports (2022)
63. Design, Synthesis, in Vitro, and in Silico Biological Evaluations of Coumarin-Indole Hybrids As New Anti-Α-Glucosidase Agents, BMC Chemistry (2022)
64. Design, Synthesis, in Vitro, and in Silico Enzymatic Evaluations of Thieno[2,3-B]Quinoline-Hydrazones As Novel Inhibitors for Α-Glucosidase, Bioorganic Chemistry (2022)
65. Docking Study, Molecular Dynamic, Synthesis, Anti-Α-Glucosidase Assessment, and Admet Prediction of New Benzimidazole-Schiff Base Derivatives, Scientific Reports (2022)
66. Fast Anisotropic Growth of the Biomineralized Zinc Phosphate Nanocrystals for a Facile and Instant Construction of Laccase@Zn3(Po4)2 Hybrid Nanoflowers, International Journal of Biological Macromolecules (2022)
67. Formulation, Characterization, and Bioactivity Assessments of a Laccase-Based Mouthwash, Journal of Drug Delivery Science and Technology (2022)
68. Hybridization of Laccase With Dendrimer-Grafted Silica-Coated Hercynite-Copper Phosphate Magnetic Hybrid Nanoflowers and Its Application in Bioremoval of Gemifloxacin, Environmental Science and Pollution Research (2022)
69. In Silico and in Vitro Studies of Thiosemicarbazone-Indole Hybrid Compounds As Potent Α-Glycosidase Inhibitors, Computational Biology and Chemistry (2022)
70. In Silico and in Vitro Studies of Thiosemicarbazone-Indole Hybrid Compounds As Potent Α-Glycosidase Inhibitors, Computational Biology and Chemistry (2022)
71. Instantaneous Synthesis and Full Characterization of Organic–Inorganic Laccase-Cobalt Phosphate Hybrid Nanoflowers, Scientific Reports (2022)
72. Laccase-Loaded Magnetic Dialdehyde Inulin Nanoparticles As an Efficient Heterogeneous Natural Polymer-Based Biocatalyst for Removal and Detoxification of Ofloxacin, Biodegradation (2022)
73. Magnetic Casein Aggregates As an Innovative Support Platform for Laccase Immobilization and Bioremoval of Crystal Violet, International Journal of Biological Macromolecules (2022)
74. Organic-Inorganic Hybrid Nanoflowers: The Known, the Unknown, and the Future, Advances in Colloid and Interface Science (2022)
75. Synthesis and Bioactivities Evaluation of Quinazolin-4(3H)-One Derivatives As Α-Glucosidase Inhibitors, BMC Chemistry (2022)
76. Synthesis, Molecular Dynamic, and in Silico Study of New Ethyl 4-Arylpyrimido[1,2-B]Indazole-2-Carboxylate: Potential Inhibitors of Α-Glucosidase, Journal of Molecular Structure (2022)
77. Synthesis, Α-Glucosidase Inhibition, in Silico Pharmacokinetic, and Docking Studies of Thieno[2,3-B]Quinoline-Acetamide Derivatives As New Anti-Diabetic Agents, ChemistrySelect (2022)
78. Ugi Adducts: Design and Synthesis of Natural-Based Α-Glucosidase Inhibitors, Letters in Organic Chemistry (2022)
79. Α-Glucosidase Inhibitors From Marrubium Astracanicum: Isolation and Molecular Docking, Revista Brasileira de Farmacognosia (2022)
80. An Organic Solvent-Tolerant Lipase of Streptomyces Pratensis Mv1 With the Potential Application for Enzymatic Improvement of N6/N3 Ratio in Polyunsaturated Fatty Acids From Fenugreek Seed Oil, Journal of Food Science and Technology (2021)
81. Bio-Removal of Phenol by the Immobilized Laccase on the Fabricated Parent and Hierarchical Nay and Zsm-5 Zeolites, Journal of the Taiwan Institute of Chemical Engineers (2021)
82. Design and Synthesis of Novel Quinazolinone-Pyrazole Derivatives As Potential Α-Glucosidase Inhibitors: Structure-Activity Relationship, Molecular Modeling and Kinetic Study, Bioorganic Chemistry (2021)
83. Design and Synthesis of Novel Quinazolinone-Pyrazole Derivatives As Potential Α-Glucosidase Inhibitors: Structure-Activity Relationship, Molecular Modeling and Kinetic Study, Bioorganic Chemistry (2021)
84. Design, Synthesis, and Α-Glucosidase-Inhibitory Activity of Phenoxy-Biscoumarin–N-Phenylacetamide Hybrids, Archiv der Pharmazie (2021)
85. Design, Synthesis, Molecular Docking, and in Vitro Α-Glucosidase Inhibitory Activities of Novel 3-Amino-2,4-Diarylbenzo[4,5]Imidazo[1,2-A]Pyrimidines Against Yeast and Rat Α-Glucosidase, Scientific Reports (2021)
86. Development of an Enzyme-Enhancer System to Improve Laccase Biological Activities, International Journal of Biological Macromolecules (2021)
87. High Efficiency of Osmotically Stable Laccase for Biotransformation and Micro-Detoxification of Levofloxacin in the Urea-Containing Solution: Catalytic Performance and Mechanism, Colloids and Surfaces B: Biointerfaces (2021)
88. Insights Into the Molecular-Level Details of Betaine Interactions With Laccase Under Various Thermal Conditions, Journal of Molecular Liquids (2021)
89. Lipase@Zeolitic Imidazolate Framework Zif-90: A Highly Stable and Recyclable Biocatalyst for the Synthesis of Fruity Banana Flavour, International Journal of Biological Macromolecules (2021)
90. New 4,5-Diphenylimidazole-Acetamide-1,2,3-Triazole Hybrids As Potent Α-Glucosidase Inhibitors: Synthesis, in Vitro and in Silico Enzymatic and Toxicity Evaluations, Monatshefte fur Chemie (2021)
91. Quinazolinone-Dihydropyrano[3,2-B]Pyran Hybrids As New Α-Glucosidase Inhibitors: Design, Synthesis, Enzymatic Inhibition, Docking Study and Prediction of Pharmacokinetic, Bioorganic Chemistry (2021)
92. Synthesis and Biological Evaluation of a New Series of Benzofuran-1,3,4-Oxadiazole Containing 1,2,3-Triazole-Acetamides As Potential Α-Glucosidase Inhibitors, Journal of Biochemical and Molecular Toxicology (2021)
93. Synthesis of 4-Alkylaminoimidazo[1,2-A]Pyridines Linked to Carbamate Moiety As Potent Α-Glucosidase Inhibitors, Molecular Diversity (2021)
94. Synthesis, in Vitro and in Silico Enzymatic Inhibition Assays, and Toxicity Evaluations of New 4,5-Diphenylimidazole-N-Phenylacetamide Derivatives As Potent Α-Glucosidase Inhibitors, Medicinal Chemistry Research (2021)
95. Synthesis, in Vitro Evaluation, and Molecular Docking Studies of Novel Hydrazineylideneindolinone Linked to Phenoxymethyl-1,2,3-Triazole Derivatives As Potential Α-Glucosidase Inhibitors, Bioorganic Chemistry (2021)
96. Synthesis, In-Vitro Evaluation, Molecular Docking, and Kinetic Studies of Pyridazine-Triazole Hybrid System As Novel Α-Glucosidase Inhibitors, Bioorganic Chemistry (2021)
97. An Efficient and Targeted Synthetic Approach Towards New Highly Substituted 6-Amino-Pyrazolo[1,5-A]Pyrimidines With Α-Glucosidase Inhibitory Activity, Scientific Reports (2020)
98. Combination of Thermal and Biological Treatments for Bio-Removal and Detoxification of Some Recalcitrant Synthetic Dyes by Betaine-Induced Thermostabilized Laccase, Environmental Technology and Innovation (2020)
99. Design and Synthesis of Novel Pyridazine N-Aryl Acetamides: In-Vitro Evaluation of Α-Glucosidase Inhibition, Docking, and Kinetic Studies, Bioorganic Chemistry (2020)
100. Design, Synthesis, Biological Evaluation, and Docking Study of New Acridine-9-Carboxamide Linked to 1,2,3-Triazole Derivatives As Antidiabetic Agents Targeting Α-Glucosidase, Journal of Heterocyclic Chemistry (2020)
101. Immobilization of Lipase on the Modified Magnetic Diatomite Earth for Effective Methyl Esterification of Isoamyl Alcohol to Synthesize Banana Flavor, 3 Biotech (2020)
102. Molecular Level Insight Into Stability, Activity, and Structure of Laccase in Aqueous Ionic Liquid and Organic Solvents: An Experimental and Computational Research, Journal of Molecular Liquids (2020)
103. New Phthalimide-Benzamide-1,2,3-Triazole Hybrids; Design, Synthesis, Α-Glucosidase Inhibition Assay, and Docking Study, Medicinal Chemistry Research (2020)
104. Osmolyte-Induced Folding and Stability of Proteins: Concepts and Characterization, Iranian Journal of Pharmaceutical Research (2019)