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Effect of Laser Cladded Co-Doped Strontium Fluorapatite Nanopowder Coating on the Antibacterial and Cell Attachment of Ti-6Al-4V Implants for Bone Applications Publisher



Ganjali M1 ; Mousavi S2 ; Nikzamir S1 ; Milan PB3 ; Mozafari M4
Authors
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Authors Affiliations
  1. 1. Biomedical Engineering Group, Nanotechnology and Advanced Materials Department, Materials and Energy Research Center, Karaj, Iran
  2. 2. Nour-zoha Materials Engineering Research Group, Tehran, Iran
  3. 3. Iran University of Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Tissue Engineering Regenerative Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran

Source: Materials Technology Published:2022


Abstract

In this study, doped strontium fluorapatite (Sr-FAP) nanopowders were synthesised by sol-gel and used as a coating to modify Ti-6Al-4V  substrates through CO2 laser cladding. The Ca ions of FAP were substituted by a different amount of Sr ions to increase bone cell differentiation and antibacterial properties. Lattice parameters and crystal size values of different samples decrease with increasing the amount of Sr ion. According to the morphological results, the laser cladding Sr doped FAP nanopowders can create homogenously and crack-free coating on the Ti-6Al-4V  substrates. The 0.6SrFAP nanopowder sample had a more hydrophilic nature in comparison to other Sr doped FAP nanopowders. This sample showed antibacterial properties and high cell adhesion, spreading, and viability while provided a bioactive and favourable surface for bone tissue regeneration. Therefore, 0.6SrFAP nanopowder laser cladding on the surface of Ti-6Al-4VV implants seems to be promising for further in-vivo investigations in bone applications. © 2021 Informa UK Limited, trading as Taylor & Francis Group.