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The Effect of Different Solvent Systems on Physical Properties of Electrospun Poly(Glycerol Sebacate)/Poly(E-Caprolactone) Blend Publisher



Atari M1, 2 ; Mohammadalizadeh Z3 ; Zargar Kharazi A2, 3 ; Haghjooy Javanmard S2
Authors
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Authors Affiliations
  1. 1. Department of Materials Engineering, Isfahan University of Technology, Isfahan, Iran
  2. 2. Applied Physiology Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Department of Biomaterials, Nanotechnology and Tissue Engineering, School of Advanced Medical Technology, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Polymer-Plastics Technology and Materials Published:2022


Abstract

Solvent type and solution viscosity are of great importance in affecting different traits of the electrospun scaffolds. This study aims to highlight the effect of different solvents on physicomechanical properties of PGS/PCL blend electrospun scaffolds. The PGS:PCL (2:1) blends were dissolved in five different solvent systems including DMF, DCM, DMSO, CF-AC, and CF-EtOH, with the final concentration of 18% w/v. Analyzing morphology indicated a more uniform fiber diameter and smaller pore size in PGS/PCL//CF-AC scaffolds. Also, the mechanical parameters were improved by the solvent upon using CF-AC more than DMF, correlated to better solution viscosity, spinnability and uniform fiber distribution. © 2022 Taylor & Francis.
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