Synthesis of Novel 2-Oxoquinoline Derivatives Via Ugi-Four-Component-Heck Reaction

Synthesis of Novel 2-Oxoquinoline Derivatives Via Ugi-Four-Component-Heck Reaction Publisher

Rasouli MA¹ ; Mahdavi M² ; Saeedi M² ; Ranjbar PR¹ ; Shafiee A² ; Foroumadi A^{2, 3}

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1. School of Chemistry, University College of Science, University of Tehran, P.O. Box 14155-6455, Tehran, Iran
2. Department of Medicinal Chemistry, Pharmaceutical Sciences Research Center, Tehran University of Medicinal Sciences, Tehran, 14176, Iran
3. Drug Design and Development Research Center, Tehran University of Medicinal Sciences, Tehran, Iran

Source: Journal of Heterocyclic Chemistry Published:2015

Abstract

The present study provides an efficient strategy for the preparation of novel N-substituted-4-methyl-quinolin-1(2H)-one derivatives via two-step Ugi/Heck reaction. The procedure is based on the Ugi coupling between 2-bromoanilines, various aromatic aldehydes, vinylacetic acid, and isocyanides, and then intramolecular Heck reaction, which leads to the formation of the title compounds in good yields. © 2014 HeteroCorporation.

Style	Citing Format
MLA	Rasouli MA, et al.. "Synthesis of Novel 2-Oxoquinoline Derivatives Via Ugi-Four-Component-Heck Reaction." Journal of Heterocyclic Chemistry, vol. 52, no. 2, 2015, pp. 386-391.
APA	Rasouli MA, Mahdavi M, Saeedi M, Ranjbar PR, Shafiee A, Foroumadi A (2015). Synthesis of Novel 2-Oxoquinoline Derivatives Via Ugi-Four-Component-Heck Reaction. Journal of Heterocyclic Chemistry, 52(2), 386-391.
Chicago	Rasouli MA, Mahdavi M, Saeedi M, Ranjbar PR, Shafiee A, Foroumadi A. "Synthesis of Novel 2-Oxoquinoline Derivatives Via Ugi-Four-Component-Heck Reaction." Journal of Heterocyclic Chemistry 52, no. 2 (2015): 386-391.
Harvard	Rasouli MA et al. (2015) 'Synthesis of Novel 2-Oxoquinoline Derivatives Via Ugi-Four-Component-Heck Reaction', Journal of Heterocyclic Chemistry, 52(2), pp. 386-391.
Vancouver	Rasouli MA, Mahdavi M, Saeedi M, Ranjbar PR, Shafiee A, Foroumadi A. Synthesis of Novel 2-Oxoquinoline Derivatives Via Ugi-Four-Component-Heck Reaction. Journal of Heterocyclic Chemistry. 2015;52(2):386-391.
BibTex	@article{ author = {Rasouli MA and Mahdavi M and Saeedi M and Ranjbar PR and Shafiee A and Foroumadi A}, title = {Synthesis of Novel 2-Oxoquinoline Derivatives Via Ugi-Four-Component-Heck Reaction}, journal = {Journal of Heterocyclic Chemistry}, volume = {52}, number = {2}, pages = {386-391}, year = {2015} }
RIS	TY - JOUR AU - Rasouli MA AU - Mahdavi M AU - Saeedi M AU - Ranjbar PR AU - Shafiee A AU - Foroumadi A TI - Synthesis of Novel 2-Oxoquinoline Derivatives Via Ugi-Four-Component-Heck Reaction JO - Journal of Heterocyclic Chemistry VL - 52 IS - 2 SP - 386 EP - 391 PY - 2015 ER -

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