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Biosensing Applications of Polyaniline (Pani)-Based Nanocomposites: A Review Publisher



Kazemi F1 ; Naghib SM1 ; Zare Y2 ; Rhee KY3
Authors
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Authors Affiliations
  1. 1. Nanotechnology Department, School of Advanced Technologies, Iran University of Science and Technology (IUST), Tehran, Iran
  2. 2. Biomaterials and Tissue Engineering Research Group, Department of Interdisciplinary Technologies, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran
  3. 3. Department of Mechanical Engineering, College of Engineering, Kyung Hee University, Yongin, South Korea

Source: Polymer Reviews Published:2021


Abstract

Conducting polyaniline (PANI) brings together the electrical conductivity of metals with intriguing properties of plastics including facile processing as well as controllable chemical and physical properties. The nanoscaled PANI has attracted intense interest in various fields owing to the great physicochemical features including high conductivity, facile preparation, and fascinating redox behavior. PANI-based nanocomposites can help biocatalysts and bioreceptors including enzymes, antigen-antibodies, cells, and nucleic acids to immobilize on the surface in order to detect analytes and allow the biosensing process to occur at room temperature. In this article, an in-depth overview of the synthesis methods of PANI-based composites, their biomedical applications as biosensors, current states, challenges, and the potential application of them in the future have been presented and discussed. Additionally, recent PANI-based biosensing devices for the detection of glucose, cholesterol, choline, virus, cancer, and bacteria have been described. © 2020 Taylor & Francis Group, LLC.
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