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A Comparative Physico-Chemical Study of Bioactive Glass and Bone-Derived Hydroxyapatite Publisher



Doostmohammadi A1, 2 ; Monshi A1 ; Fathi MH1 ; Braissant O3
Authors
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Authors Affiliations
  1. 1. Biomaterials Group, Materials Engineering Department, Isfahan University of Technology, Isfahan 84156-83111, Iran
  2. 2. Isfahan University of Medical Science, Isfahan 81746-73461, Iran
  3. 3. Laboratory of Biomechanics and Biocalorimetry, Coalition for Clinical Morphology and Biomedical Engineering, University of Basel, Basel, Switzerland

Source: Ceramics International Published:2011


Abstract

This study aimed at comparing the physico-chemical properties of bioactive glass and bone-derived hydroxyapatite (HA). 63S bioglass particles were obtained by sol-gel process and HA samples were derived from bovine bone. The chemical composition and the crystalline structure of both bioceramics were evaluated. Then the zeta potential in physiological saline and at different pH values was determined. It was found that the negativity of zeta potential for 63S bioglass is higher than that of bone-derived HA. The exothermal behavior through the hydration process was evaluated by isothermal microcalorimetry. The results showed that the librated heat during bioactive glass hydration process and its rate are almost ten times higher than HA. It could be related to different hydration mechanisms of bioglass and HA. However, for both bioglass and HA, this value is in the safe range and cannot be harmful for the adjacent tissues in the body. © 2011 Elsevier Ltd and Techna Group S.r.l.
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