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Isfahan University of Medical Sciences

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Faculty Members have conducted research related to the Cycloartanes From Euphorbia Aellenii Rech. F. and Their Antiproliferative Activity

Mahmoud Aghaei

Mahmoud Aghaei

Professor of Clinical Biochemistry

Department of Clinical Biochemistry, School of Pharmacy and Pharmaceutical Sciences

Pharmaceutical Sciences Research Center

Isfahan University of Medical Sciences

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64. Sesquiterpene Lactones From Shoot Culture of Artemisia Aucheri With Cytotoxicity Against Prostate and Breast Cancer Cells, Research in Pharmaceutical Sciences (2019)

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70. Estrogen Stimulates Adenosine Receptor Expression Subtypes in Human Breast Cancer Mcf-7 Cell Line, Research in Pharmaceutical Sciences (2018)

71. Galectin-9 Induces Apoptosis in Ovcar-3 Ovarian Cancer Cell Through Mitochondrial Pathway, Research in Pharmaceutical Sciences (2018)

72. Leptin Induces Matrix Metalloproteinase 7 Expression to Promote Ovarian Cancer Cell Invasion by Activating Erk and Jnk Pathways, Journal of Cellular Biochemistry (2018)

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74. Pimpinelol, a Novel Atypical Sesquiterpene Lactone From Pimpinella Haussknechtii Fruits With Evaluation of Endoplasmic Reticulum Stress in Breast Cancer Cells, Fitoterapia (2018)

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76. The Protective Role of Melatonin in Cadmium-Induced Proliferation of Ovarian Cancer Cells, Research in Pharmaceutical Sciences (2018)

77. A3 Adenosine Receptor Agonist Induce G1 Cell Cycle Arrest Via Cyclin D and Cyclin-Dependent Kinase 4 Pathways in Ovcar-3 and Caov-4 Cell Lines, Journal of Cancer Research and Therapeutics (2017)

78. A3 Adenosine Receptor Agonist Inhibited Survival of Breast Cancer Stem Cells Via Gli-1 and Erk1/2 Pathway, Journal of Cellular Biochemistry (2017)

79. Apoptosis and Cell Cycle Regulatory Effects of Adenosine by Modulation of Gli-1 and Erk1/2 Pathways in Cd44+ and Cd24− Breast Cancer Stem Cells, Cell Proliferation (2017)

80. Association of Serum Microrna-21 Levels With Visfatin, Inflammation, and Acute Coronary Syndromes, Heart and Vessels (2017)

81. Dihydroartemisinin Induces Apoptosis in Human Bladder Cancer Cell Lines Through Reactive Oxygen Species, Mitochondrial Membrane Potential, and Cytochrome C Pathway, International Journal of Preventive Medicine (2017)

82. Effect of Pufas Oral Administration on the Amount of Apoptotic Caspases Enzymes in Gastric Cancer Patients Undergoing Chemotherapy, Anti-Cancer Agents in Medicinal Chemistry (2017)

83. Induction of G2/M Phase Arrest and Apoptosis by a New Tetrahydroingenol Diterpenoid From Euphorbia Erythradenia Bioss. in Melanoma Cancer Cells, Biomedicine and Pharmacotherapy (2017)

84. Jatropha-6(17),11 E -Diene Class Derivatives Induce Apoptosis Effects in Ovcar-3 and Caov-4 Ovarian Cancer Cell Lines Via a Mitochondrial Pathway, Biochemistry and Cell Biology (2017)

85. New 6(17)-Epoxylathyrane Diterpene: Aellinane From Euphorbia Aellenii Induces Apoptosis Via Mitochondrial Pathway in Ovarian Cancer Cell Line, Toxicology Mechanisms and Methods (2017)

86. New 6(17)-Epoxylathyrane Diterpene: Aellinane From Euphorbia Aellenii Induces Apoptosis Via Mitochondrial Pathway in Ovarian Cancer Cell Line, Toxicology Mechanisms and Methods (2017)

87. Rhoa/Rock Pathway Mediates Leptin-Induced Upa Expression to Promote Cell Invasion in Ovarian Cancer Cells, Cellular Signalling (2017)

88. Aptamer-Conjugated Magnetic Nanoparticles As Targeted Magnetic Resonance Imaging Contrast Agent for Breast Cancer, Journal of Medical Signals and Sensors (2016)

89. Bioactivity-Guided Isolation of New Antiproliferative Compounds From Juniperus Foetidissima Willd, Natural Product Research (2016)

90. New Macrocyclic Diterpenes From Euphorbia Connata Boiss. With Cytotoxic Activities on Human Breast Cancer Cell Lines, Natural Product Research (2016)

91. Obtusifoliol Related Steroids From Euphorbia Sogdiana With Cell Growth Inhibitory Activity and Apoptotic Effects on Breast Cancer Cells (Mcf-7 and Mda-Mb231), Steroids (2016)

92. The Effect of Ω-Fatty Acids on the Expression of Phospholipase A2 Group 2A in Human Gastric Cancer Patients, Journal of Research in Medical Sciences (2016)

93. The Role of Serum Levels of Microrna-21 and Matrix Metalloproteinase-9 in Patients With Acute Coronary Syndrome, Molecular and Cellular Biochemistry (2016)

94. Activation of A2b Adenosine Receptor Regulates Ovarian Cancer Cell Growth: Involvement of Bax/Bcl-2 and Caspase-3, Biochemistry and Cell Biology (2015)

95. Britannin, a Sesquiterpene Lactone, Inhibits Proliferation and Induces Apoptosis Through the Mitochondrial Signaling Pathway in Human Breast Cancer Cells, Tumor Biology (2015)

96. Cadmium Induces Reactive Oxygen Species-Dependent Apoptosis in Mcf-7 Human Breast Cancer Cell Line, Toxicology Mechanisms and Methods (2015)

97. Cytotoxic Activities of Euphorbia Kopetdaghi Against Ovcar-3 and Ej-138 Cell Lines, Journal of HerbMed Pharmacology (2015)

98. Evaluating T-Cell Immunoglobulin Mucin-3 (Tim-3) Receptor in the Growth Inhibition of Acute Lymphoblastic Leukemia (All) Cell Lines, Journal of Isfahan Medical School (2015)

99. Expression of Adenosine Receptor Subclasses in Malignant and Adjacent Normal Human Prostate Tissues, Prostate (2015)

100. Herbal Extracts Induce Dermal Papilla Cell Proliferation of Human Hair Follicles, Annals of Dermatology (2015)

101. Herbal Extracts Induce Dermal Papilla Cell Proliferation of Human Hair Follicles, Annals of Dermatology (2015)

102. Molecular Expression of Adenosine Receptors in Ovcar-3, Caov-4 and Skov-3 Human Ovarian Cancer Cell Lines, Research in Pharmaceutical Sciences (2015)

103. Molecular Mechanism of Apoptosis Induction by Gaillardin, a Sesquiterpene Lactone, in Breast Cancer Cell Lines: Gaillardin-Induced Apoptosis in Breast Cancer Cell Lines, Cell Biology and Toxicology (2015)

104. New Jatrophane Diterpenes From Euphorbia Osyridea With Proapoptotic Effects on Ovarian Cancer Cells, Phytochemistry Letters (2015)

105. Cycloartane Triterpenoids From Euphorbia Macrostegia With Their Cytotoxicity Against Mda-Mb48 and Mcf-7 Cancer Cell Lines, Iranian Journal of Pharmaceutical Research (2014)

106. Investigation of Cadmium Chloride Cytotoxic Effect in Mcf-7 Breast Cancer Cell Line, Journal of Isfahan Medical School (2014)

107. Mitochondrial and Caspase Pathways Are Involved in the Induction of Apoptosis by Ib-Meca in Ovarian Cancer Cell Lines, Tumor Biology (2014)

108. Adenosine Induces Cell Cycle Arrest and Apoptosis Via Cyclind1/Cdk4 and Bcl-2/Bax Pathways in Human Ovarian Cancer Cell Line Ovcar-3, Tumor Biology (2013)

109. Combination of Herbal Extracts and Platelet-Rich Plasma Induced Dermal Papilla Cell Proliferation: Involvement of Erk and Akt Pathways, Journal of Cosmetic Dermatology (2013)

110. Intakes of Vegetables and Fruits Are Negatively Correlated With Risk of Stroke in Iran, International Journal of Preventive Medicine (2013)

111. Quercetin Supplementation Does Not Attenuate Exercise Performance and Body Composition in Young Female Swimmers, International Journal of Preventive Medicine (2013)

112. Unusual Ingenoids From Euphorbia Erythradenia Bioss. With Pro-Apoptotic Effects, Fitoterapia (2013)

113. Adenosine Induces Cell-Cycle Arrest and Apoptosis in Androgen-Dependent And-Independent Prostate Cancer Cell Lines, Lncap-Fgc-10, Du-145, and Pc3, Prostate (2012)

114. Evaluation of Pde5 and Pde9 Expression in Benign and Malignant Breast Tumors, Archives of Medical Research (2012)

115. Inhibition of Phosphodiestrase 9 Induces Cgmp Accumulation and Apoptosis in Human Breast Cancer Cell Lines, Mcf-7 and Mda-Mb-468, Cell Proliferation (2012)

116. Molecular Mechanisms of A3 Adenosine Receptor-Induced G1 Cell Cycle Arrest and Apoptosis in Androgen-Dependent and Independent Prostate Cancer Cell Lines: Involvement of Intrinsic Pathway, Journal of Cancer Research and Clinical Oncology (2011)