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Effect of Polymer Molecular Weight on Morphology and Particle Size of Chitosan Microspheres Prepared Via Spray Drying Method Publisher



Taranejoo S1, 2 ; Rafienia M3 ; Janmaleki M1 ; Kamali M4 ; Sadeghzadeh L1
Authors
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Authors Affiliations
  1. 1. Nanomedicine and Tissue Engineering Research Center, Shahid Beheshti University (M.C), Tehran, Iran
  2. 2. School of Chemical Engineering, University of Tehran, Tehran, Iran
  3. 3. Tissue Engineering Lab., Faculty of Medicine, Isfahan University of Medical Science, Soffe Isfahan, Iran
  4. 4. Baghiatallah University of Medical Sciences, Tehran, Iran

Source: IFMBE Proceedings Published:2009


Abstract

Chitosan microspheres for biological applications were prepared by spray-drying method. Two kinds of chitosan with different molecular weigh were used and their characteristics were compared. Scanning electron microscopy was applied to study morphology of the particles. We saw most of the chitosan microparticles had spherical or pseudospherical shape. It is found out that Smoothness and sphericity of the particles were significantly increased by the enhancement of chitosan molecular weight. © 2009 Springer-Verlag.
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