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Evaluation of Physical, Mechanical, and Biodegradation of Chitosan/Graphene Oxide Composite As Bone Substitutes Publisher



Tavakoli M1 ; Karbasi S1 ; Soleymani Eil Bakhtiari S2
Authors
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Authors Affiliations
  1. 1. Biomaterials and Tissue Engineering Department, School of Advanced Technology in Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Advanced Materials Research Center, Department of Materials Engineering, Najafabad Branch, Islamic Azad University, Najafabad, Iran

Source: Polymer-Plastics Technology and Materials Published:2020


Abstract

In this study, a nanocomposite was prepared from chitosan (Cs) and graphene oxide (GO) with different percentages. The results of Fourier-transform infrared spectroscopy, thermal gravity analysis, and X-ray diffraction showed that the presence of GO nanoparticles increased thermal stability and crystallinity of Cs. Tensile test results showed that the presence of 0.3 wt.% GO in Cs film increased the tensile strength and Young’s modulus by 296% and 193%, respectively. The results of bioactivity and biodegradation test showed that the presence of GO in Cs film increased the density of the apatite-like layer on the surface and the degradation time. © 2019, © 2019 Taylor & Francis.
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